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The map label for this gene is frr [H]

Identifier: 148826547

GI number: 148826547

Start: 1591765

End: 1592286

Strand: Direct

Name: frr [H]

Synonym: CGSHiEE_08020

Alternate gene names: 148826547

Gene position: 1591765-1592286 (Clockwise)

Preceding gene: 148826546

Following gene: 148826548

Centisome position: 87.8

GC content: 37.55

Gene sequence:

>522_bases
ATGGAAAAAAGCCTTGAAGCATTAAAAGGTCATATTTCAAAAATTCGTACTGGTCGTGCGCAACCGAGTTTACTTGATGC
AATTCAAGTTGAATATTACGGTGCAGCAACGCCACTTCGCCAATTAGCAAACGTAGTGGCAGAAGATGCGCGTACTTTAG
CTGTAACTGTTTTTGATCGTTCTTTAATCTCTGCAGTAGAAAAAGCCATTTTAACCTCAGATTTAGGTTTAAACCCATCT
TCAGCGGGTACCACAATCCGTGTTCCACTTCCGCCATTAACAGAAGAACGCCGTCGCAATTTAATCAAGATCGTAAAAGG
CGAAGGTGAACAAGGTAAAGTTGCGATTCGCAACGTACGTCGTGATGCGAATGATAAAATCAAAGCATTATTAAAAGACA
AAGAAATCAGCGAAAACGAACAACATAAAGCAGAAGAAGAAATCCAAAAAATCACAGATATTTACATTAAAAAAGTAGAT
GAAGTATTAGCGGATAAAGAAAAAGAATTAATGGATTTCTAA

Upstream 100 bases:

>100_bases
ATTTAAAAAAATCCAGTAAAATCACGGCGTTCTAACTTTCATCAATTAAAAAGGACAATGCAATGCTTAACCAAATTAAA
AAAAGAATGCTCAAGATCGT

Downstream 100 bases:

>100_bases
TCATCAAAAAATACGAAAGGCAGACAGTTTTGTCTGCCTTTATTTTATTAGGTATGCGAATTTAGACGTATCAATGAAAA
TATAATCAACAAAGTGCGGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEKAILTSDLGLNPS
SAGTTIRVPLPPLTEERRRNLIKIVKGEGEQGKVAIRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVD
EVLADKEKELMDF

Sequences:

>Translated_173_residues
MEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEKAILTSDLGLNPS
SAGTTIRVPLPPLTEERRRNLIKIVKGEGEQGKVAIRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVD
EVLADKEKELMDF
>Mature_173_residues
MEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEKAILTSDLGLNPS
SAGTTIRVPLPPLTEERRRNLIKIVKGEGEQGKVAIRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVD
EVLADKEKELMDF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=32.7586206896552, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32.6666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=173, Percent_Identity=68.7861271676301, Blast_Score=251, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=31.7919075144509, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 19300; Mature: 19300

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRNLIKIVKGEGEQGKVAIRNVR
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
RDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVDEVLADKEKELMDF
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRNLIKIVKGEGEQGKVAIRNVR
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
RDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVDEVLADKEKELMDF
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA