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The map label for this gene is moeB [H]

Identifier: 148825992

GI number: 148825992

Start: 990703

End: 991434

Strand: Direct

Name: moeB [H]

Synonym: CGSHiEE_04845

Alternate gene names: 148825992

Gene position: 990703-991434 (Clockwise)

Preceding gene: 148825991

Following gene: 148825993

Centisome position: 54.64

GC content: 39.89

Gene sequence:

>732_bases
ATGATCGAACTTAGTCACGAAGAAGAATTGCGTTATAACCGTCAAATTATTCTTAAAAGCGTAGATTTTGACGGGCAAGA
AAAACTTAAAGCAAGCAAAATGCTGATCGTTGGGCTTGGTGGCTTAGGATGTGCAGCCAGCCAATATCTCGCAGCGGCAG
GCGTTGGAAATTTAACACTGTTGGATTTCGATACAGTTTCGCTTTCGAATCTTCAACGACAAGTCCTACACTGCGATACG
CGCTTGAATATGCCAAAGGTGGAATCCGCTAAAATTGCACTGGAACAAATCAATCCACATATAAACATAGAGACGATTAA
TGCGAAGTTGGACGAAGAAAAACTGGCTGAAATCATTCCGCACTTTGATATTGTTTTAGATTGTACAGACAATGTGGAAA
TCCGTAATCAATTGGATCGCCAATGTAATCATGCAAAAATTCCTCTTATTTCTGGTGCTGCAATTCGAATGGAAGGTCAG
GTTTCCGTTTTCACTTATGAACCAAATACGCCTACTTATCGTGATCTCAGCAAATTATTTGGACAAAATGTATTAAGCTG
TGTGGAAGCTGGCGTGCTTGCACCAATCGTCGGTATTGTGGGCTGCATTCAAGCCTTAGAAGCAATTAAAGTGCGGTTAA
AAATCGGTAAGAATTTGTGTGGACGCTTATTGATGATTGACGGTTTTTCGATGAATATTCGAGAAATTAAACTTCCAACC
AATATGGAATAA

Upstream 100 bases:

>100_bases
AAAAAGCAATTGTTTTATCGTGTTAGAACAAGAACGTGGCAATGTCTCTGCGGGCGAAACAGTGACAATTGAGCCTTTCA
ATCATTTATTAGGATAAAAA

Downstream 100 bases:

>100_bases
AACGCTTCAAAAGAGAAAAAAATTTAACCGCACTTTTATTAACCATAACCTTTACGACAAAACACTATGACAACAGAAAT
TAAAAAACTTAGATCCCGAT

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDT
RLNMPKVESAKIALEQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME

Sequences:

>Translated_243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDT
RLNMPKVESAKIALEQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME
>Mature_243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDT
RLNMPKVESAKIALEQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=228, Percent_Identity=39.4736842105263, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI23510338, Length=162, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI23510340, Length=162, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4885649, Length=138, Percent_Identity=31.1594202898551, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787048, Length=241, Percent_Identity=63.9004149377593, Blast_Score=322, Evalue=1e-89,
Organism=Escherichia coli, GI87082356, Length=235, Percent_Identity=40.4255319148936, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789177, Length=139, Percent_Identity=28.7769784172662, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540406, Length=237, Percent_Identity=38.8185654008439, Blast_Score=179, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI193203301, Length=139, Percent_Identity=35.2517985611511, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321903, Length=241, Percent_Identity=37.7593360995851, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6322639, Length=165, Percent_Identity=31.5151515151515, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582879, Length=238, Percent_Identity=46.6386554621849, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24660640, Length=139, Percent_Identity=33.0935251798561, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573937, Length=161, Percent_Identity=31.055900621118, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26882; Mature: 26882

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTL
CCCCCCHHHHHHCCEEEEEECCCCCHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEE
LDFDTVSLSNLQRQVLHCDTRLNMPKVESAKIALEQINPHINIETINAKLDEEKLAEIIP
EEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
HFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQVSVFTYEPNTPTYRDLSKLF
CCEEEEECCCCCHHHHHHHHCCCCCCCEEECCCEEEEECEEEEEEECCCCCCHHHHHHHH
GQNVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCEEEEECCC
NME
CCC
>Mature Secondary Structure
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTL
CCCCCCHHHHHHCCEEEEEECCCCCHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEE
LDFDTVSLSNLQRQVLHCDTRLNMPKVESAKIALEQINPHINIETINAKLDEEKLAEIIP
EEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
HFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQVSVFTYEPNTPTYRDLSKLF
CCEEEEECCCCCHHHHHHHHCCCCCCCEEECCCEEEEECEEEEEEECCCCCCHHHHHHHH
GQNVLSCVEAGVLAPIVGIVGCIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCEEEEECCC
NME
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]