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The map label for this gene is uup-A [H]

Identifier: 148825883

GI number: 148825883

Start: 876901

End: 878844

Strand: Direct

Name: uup-A [H]

Synonym: CGSHiEE_04240

Alternate gene names: 148825883

Gene position: 876901-878844 (Clockwise)

Preceding gene: 148825882

Following gene: 148825888

Centisome position: 48.37

GC content: 39.56

Gene sequence:

>1944_bases
GTGGCATTAATTAGTTTAACCAATGGATATCTTTCCTTTAGTGATGCGCCTTTGTTAGATCACGCAGAACTACATATTGA
ACCGAATGAACGTGTTTGTTTAGTTGGGCGTAACGGTGCAGGTAAATCAACTTTATTGAAAATCATCGCAGGCGATGTGC
TTATGGATGATGGCAAAATCCAATACGAAAAAGATCTTGTGGTTTCTCGTTTAGAACAAGACCCACTGCGTAATGCGCAA
GACAATATTTTTGATTATGTCGCGGAAGGTGTTGGGCATTTAACGGATTTATTGAAAGAATATCATCATATTTCTGTTCA
ATTGGAAGAAAATTACAGTGATCAAATTTTAAGTCAATTAGAGCAAGTTCAGGCTAAATTAGAACACGCTGATGGCTGGC
GATTTGAAAATAAAATCAATGAAGTATTGTTAAAACTAGGTTTAAATCCAAACACAAAATTATCCGCACTTTCGGGCGGT
TGGTTACGTAAAGCGGCACTAGCACGCGCATTGGTGTGCGATCCTGATGTGTTATTACTTGATGAACCAACCAACCACTT
GGATGTGGAAGCTATTGAATGGCTGGAAAATTTCTTACTGGATTTCCAAGGTAGCATTGTATTTATTTCCCATGACCGTT
CTTTTATTCGCAAAATGGCAACACGCATTGTGGATTTAGATCGCGGTCAATTGCAGTCTTATCTAGGCAATTACGATTTA
TATTTAACCACGAAAGAAGAAAATCTACGCGTTGAAGCCTTGCAAAATGAATTATTTGATAAACGTCTTGCACAGGAAGA
AGTGTGGATTCGCCAAGGTATCAAGGCTCGCCGCACAAGAAATGAAGGGCGAGTGCGAGCATTAAAAGCGATGCGGGAGG
AACGCCGCCAACGCCGTGACGTAATGGGAACAGCCAAATTACAGTTAGATACCTCAAGTCGTTCTGGCAAAATTGTCTTT
GAAATGGAAGATGTGAGCTATGAAATCGCAGGAAAAACCTTGTTAAAAGATTTTTCAACAACGATTTTACGTGGAGATAA
AATTGCACTTGTTGGGGCAAATGGCTGTGGGAAAACCACGTTCATTAAATTATTGCTGGGGGAAATTCAGCCTACATCAG
GCAAAATCCGTTGTGGTACCAAATTAGAGATTGCTTATTTTGACCAATACCGTGCTGATTTAGATCCTGAAAAAACTGTA
ATGGATAATGTGGCGGATGGCAAACAAGATATTGAAGTCAATGGTGTAAAACGCCACGTGCTAGGGTATTTGCAAGATTT
CTTGTTCCCACCAAAACGTGCACTGATCCCAGTTAAAGCCTTATCGGGGGGAGAACGAAATCGTTTATTGCTCGCAAAAT
TATTACTCAAACCAAATAATTTATTGATTCTTGACGAACCGACCAATGACCTTGATGTAGAAACATTGGAGCTTTTAGAA
GAAATTTTGACTGATTATCAAGGCACATTGTTAATTGTGAGCCACGACCGTCAATTTATCGATAATACTGCCACAGAATG
TTATTTATTCGAAGGTGAAGGGCATTTGAATAAGTATGTGGGAGGATTCTGTGATGCGAAACAGCAACAAGCCAATTTCT
GGGCAAGTAAAGCAGTGGAAGAACAGGCTAAAGCGAAGAAATCTGAACCACTAAAAGAAGAAAGTGCGGTGAAAAATGAC
CGCACTTCTAAGCCGAAATCCGTGAAACTTTCTTATAAAGAACAACGAGAGCTAGAACAACTTCCACAACTATTGGAAGA
GTTGGAAACTAAAATTACCGTACTTCAAGCTGAAATAGCCGATCCAGCATTTTTCCAACAGGCTCACGATATTACCGACG
CTAAATTAAAAGAATTGGCGGATACTGAAGCCGAATTAGAAACAGCATTTTTACGCTGGGAAGAATTGGAAGAAAAGAAA
AATTTGACTGACGGTAAAGCTTAA

Upstream 100 bases:

>100_bases
ACTTTGATTTAAGAGCTAATCCCATCGAATTGATGGGATTTTTTATGCAAACCGTATAGAATAGTGCGGTTAATTTTCAC
TGAATTTTTATGGGGCAGTT

Downstream 100 bases:

>100_bases
AAAATAACGCCCGAAAGGGCGTTTTTATTTAGAGGAAATATTGCACAGAATCAGATTTTAATTCTTTGCTAATTGACCAA
TTATTTTGCTGCTTTTAATT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPLRNAQ
DNIFDYVAEGVGHLTDLLKEYHHISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVF
EMEDVSYEIAGKTLLKDFSTTILRGDKIALVGANGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTV
MDNVADGKQDIEVNGVKRHVLGYLQDFLFPPKRALIPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGHLNKYVGGFCDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKND
RTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKELADTEAELETAFLRWEELEEKK
NLTDGKA

Sequences:

>Translated_647_residues
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPLRNAQ
DNIFDYVAEGVGHLTDLLKEYHHISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVF
EMEDVSYEIAGKTLLKDFSTTILRGDKIALVGANGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTV
MDNVADGKQDIEVNGVKRHVLGYLQDFLFPPKRALIPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGHLNKYVGGFCDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKND
RTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKELADTEAELETAFLRWEELEEKK
NLTDGKA
>Mature_646_residues
ALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPLRNAQD
NIFDYVAEGVGHLTDLLKEYHHISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGW
LRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDLY
LTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVFE
MEDVSYEIAGKTLLKDFSTTILRGDKIALVGANGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTVM
DNVADGKQDIEVNGVKRHVLGYLQDFLFPPKRALIPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEE
ILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGHLNKYVGGFCDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDR
TSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKELADTEAELETAFLRWEELEEKKN
LTDGKA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=533, Percent_Identity=31.3320825515947, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI27881506, Length=563, Percent_Identity=29.3072824156306, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI10947137, Length=563, Percent_Identity=29.3072824156306, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI69354671, Length=550, Percent_Identity=30.7272727272727, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=30.7272727272727, Blast_Score=189, Evalue=7e-48,
Organism=Escherichia coli, GI1787182, Length=641, Percent_Identity=65.5226209048362, Blast_Score=821, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=33.8374291115312, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1787041, Length=509, Percent_Identity=31.6306483300589, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1789751, Length=634, Percent_Identity=28.8643533123028, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=32.1243523316062, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788506, Length=536, Percent_Identity=24.6268656716418, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=205, Percent_Identity=33.1707317073171, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788225, Length=243, Percent_Identity=26.7489711934156, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788761, Length=235, Percent_Identity=28.936170212766, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787712, Length=269, Percent_Identity=26.0223048327138, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790190, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790467, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789672, Length=266, Percent_Identity=24.812030075188, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789962, Length=216, Percent_Identity=28.2407407407407, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786872, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786975, Length=216, Percent_Identity=28.7037037037037, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787758, Length=177, Percent_Identity=29.3785310734463, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787164, Length=219, Percent_Identity=31.9634703196347, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787500, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789873, Length=238, Percent_Identity=26.890756302521, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789891, Length=225, Percent_Identity=25.7777777777778, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786563, Length=249, Percent_Identity=26.9076305220884, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788450, Length=206, Percent_Identity=30.0970873786408, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=556, Percent_Identity=28.0575539568345, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=29.7912713472486, Blast_Score=201, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=563, Percent_Identity=31.6163410301954, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17511077, Length=291, Percent_Identity=27.4914089347079, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=246, Percent_Identity=28.4552845528455, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=29.6435272045028, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=29.4117647058824, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6325030, Length=385, Percent_Identity=28.8311688311688, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323278, Length=384, Percent_Identity=26.8229166666667, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=389, Percent_Identity=27.7634961439589, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24666836, Length=535, Percent_Identity=31.214953271028, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24641342, Length=551, Percent_Identity=29.4010889292196, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24642252, Length=559, Percent_Identity=28.9803220035778, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI18859989, Length=559, Percent_Identity=28.9803220035778, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653245, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73378; Mature: 73247

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKI
CEEEEEECCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCE
QYEKDLVVSRLEQDPLRNAQDNIFDYVAEGVGHLTDLLKEYHHISVQLEENYSDQILSQL
EEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHH
EQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGWLRKAALARALVCDPDVLLL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
ECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGANGCGKTT
CCCEEEEEEECCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
FIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTVMDNVADGKQDIEVNGVKRHV
HHHHHHHHCCCCCCCEEECCEEEEEEEHHHHCCCCHHHHHHHHHCCCCCCEEECHHHHHH
LGYLQDFLFPPKRALIPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCCHHEEEEHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGHLNKYVGGFCDAKQQQANFWASKAVE
HHHHCCCCEEEEEECCHHHHCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
EQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIA
HHHHHHCCCCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEEHHHC
DPAFFQQAHDITDAKLKELADTEAELETAFLRWEELEEKKNLTDGKA
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKI
EEEEEECCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCE
QYEKDLVVSRLEQDPLRNAQDNIFDYVAEGVGHLTDLLKEYHHISVQLEENYSDQILSQL
EEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHH
EQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGWLRKAALARALVCDPDVLLL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
ECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGANGCGKTT
CCCEEEEEEECCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
FIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKTVMDNVADGKQDIEVNGVKRHV
HHHHHHHHCCCCCCCEEECCEEEEEEEHHHHCCCCHHHHHHHHHCCCCCCEEECHHHHHH
LGYLQDFLFPPKRALIPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCCHHEEEEHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGHLNKYVGGFCDAKQQQANFWASKAVE
HHHHCCCCEEEEEECCHHHHCCCCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
EQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIA
HHHHHHCCCCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEEHHHC
DPAFFQQAHDITDAKLKELADTEAELETAFLRWEELEEKKNLTDGKA
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]