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The map label for this gene is map [H]

Identifier: 148825739

GI number: 148825739

Start: 697899

End: 698705

Strand: Direct

Name: map [H]

Synonym: CGSHiEE_03440

Alternate gene names: 148825739

Gene position: 697899-698705 (Clockwise)

Preceding gene: 148825733

Following gene: 148825740

Centisome position: 38.49

GC content: 39.28

Gene sequence:

>807_bases
ATGGCTATTCCAATTAGAACTGAAAAAGAAATTGTAAAATTACGTGAGGTCTGCAAATTGGCTTCCGATGTGCTTGTGAT
GATTGAACCTTACGTAAAAGCAGGCGTAACCACAGGCGAACTTGATCGCATTTGCCATGAATATATGGTAAATGAACAAA
AGGTTATTCCTGCTTGTTTGAATTATCATGGTTTCCCAAAGGCGACCTGTATTTCCATTAACGAAGTCGTCTGTCACGGT
ATTCCAAGTGATGATAAAGTGTTAAAAAATGGCGATATTATGAATATTGATGTTACCGTGATTAAAGACGGTTATTTTGG
CGATAACTCAAAAATGTATATCGTGGGCGGAGAAACAAATATTCGTAGTAAAAAATTAGTGGAAGCGGCACAAGAAGCAT
TATATGTTGGGATACGCACTGTAAAACCCGATATTCGTTTAAATGAAATAGGTAAAGCTGTGCAAAAATATACGGAAAGC
CAGACTTTCAGCGTTGTGCGTGAATATTGCGGACACGGCGTTGGTACGGAATTTCACTGCGAACCTCAAGTATTGCATTA
TTACGCAGATGATGGTGGCGTGATTTTAAAACCCGGAATGGTGTTTACCATTGAACCAATGATTAACGCAGGCAAAAAAG
AAGTGCGCGTGATGGGAGATGGTTGGACAGTAAAAACCAAAGATCGTAGCCATTCAGCACAATACGAACATCAACTTGTT
GTCACGGAAACTGGTTGTGAAGTAATGACTATCCGCGATGAAGAAATTGCAGAAGGTCGAATTTCACGGATTATGATTAA
TGTGTAA

Upstream 100 bases:

>100_bases
ATTATCTAATAACCCTTTACTCCATTCAAGTGCAATCCAGTTTTTTCCTAGAAATCGTGCTATAATCTCGCAAAGTTTTT
TTCAAAAAAGTGAGATAAAA

Downstream 100 bases:

>100_bases
TTGACATTAAATTATAAGCAAGGGCGTAGATATACGCCCTTTTTGTTTTTCTTTATAATAAAGCCACTTCTAACCACTAA
AGGGCAATCAACATGCTGTT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAIPIRTEKEIVKLREVCKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACLNYHGFPKATCISINEVVCHG
IPSDDKVLKNGDIMNIDVTVIKDGYFGDNSKMYIVGGETNIRSKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTES
QTFSVVREYCGHGVGTEFHCEPQVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLV
VTETGCEVMTIRDEEIAEGRISRIMINV

Sequences:

>Translated_268_residues
MAIPIRTEKEIVKLREVCKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACLNYHGFPKATCISINEVVCHG
IPSDDKVLKNGDIMNIDVTVIKDGYFGDNSKMYIVGGETNIRSKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTES
QTFSVVREYCGHGVGTEFHCEPQVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLV
VTETGCEVMTIRDEEIAEGRISRIMINV
>Mature_267_residues
AIPIRTEKEIVKLREVCKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACLNYHGFPKATCISINEVVCHGI
PSDDKVLKNGDIMNIDVTVIKDGYFGDNSKMYIVGGETNIRSKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTESQ
TFSVVREYCGHGVGTEFHCEPQVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLVV
TETGCEVMTIRDEEIAEGRISRIMINV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=44, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=38.1526104417671, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1786364, Length=262, Percent_Identity=64.1221374045801, Blast_Score=354, Evalue=4e-99,
Organism=Escherichia coli, GI1788728, Length=219, Percent_Identity=25.1141552511416, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=43.8247011952191, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323273, Length=262, Percent_Identity=42.7480916030534, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21355531, Length=252, Percent_Identity=43.2539682539683, Blast_Score=210, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24583427, Length=250, Percent_Identity=41.6, Blast_Score=203, Evalue=9e-53,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29957; Mature: 29826

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPIRTEKEIVKLREVCKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACL
CCCCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHH
NYHGFPKATCISINEVVCHGIPSDDKVLKNGDIMNIDVTVIKDGYFGDNSKMYIVGGETN
CCCCCCCEEEEEEHHHEECCCCCCCCEECCCCEEEEEEEEEECCEECCCCEEEEECCCCC
IRSKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTESQTFSVVREYCGHGVGTEFHC
CCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEC
EPQVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLV
CCEEEEEEECCCCEEECCCEEEEEEHHHCCCCEEEEEEECCEEEEECCCCCCCCCCEEEE
VTETGCEVMTIRDEEIAEGRISRIMINV
EEECCCEEEEECCHHHHCCCEEEEEEEC
>Mature Secondary Structure 
AIPIRTEKEIVKLREVCKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACL
CCCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHH
NYHGFPKATCISINEVVCHGIPSDDKVLKNGDIMNIDVTVIKDGYFGDNSKMYIVGGETN
CCCCCCCEEEEEEHHHEECCCCCCCCEECCCCEEEEEEEEEECCEECCCCEEEEECCCCC
IRSKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTESQTFSVVREYCGHGVGTEFHC
CCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEC
EPQVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLV
CCEEEEEEECCCCEEECCCEEEEEEHHHCCCCEEEEEEECCEEEEECCCCCCCCCCEEEE
VTETGCEVMTIRDEEIAEGRISRIMINV
EEECCCEEEEECCHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]