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The map label for this gene is citXG [H]

Identifier: 148825698

GI number: 148825698

Start: 643219

End: 644616

Strand: Direct

Name: citXG [H]

Synonym: CGSHiEE_03205

Alternate gene names: 148825698

Gene position: 643219-644616 (Clockwise)

Preceding gene: 148825697

Following gene: 148825699

Centisome position: 35.48

GC content: 37.55

Gene sequence:

>1398_bases
TTGCAGCATTTTTTTACGACATTCTCTACAAAGGGTTCAGAAATTTCACTTGAAGCATTACTTAATGCTCGAGAGGAACG
TGCAATTTTACAACAACAGCTTATAACACAATATGGACAAACCTTACTTTGCATCACTTTAACTGCTGTGGGTGGAGTAA
AAAAAAATGCTTTGTTGGATTATGTTTTTAGAAAAGCTCTAGAAAATCTGACCGCACTTTTTACTCAGTTAAACATTACA
GCAGTAAAAGAAATAATCCGTCCGTTAGAAACGGGGCATGAAGCCTATTTTGTATTACCGATAGATGCTCGTACGCTAAA
AGTGCTGATGATTGAATTGGAAGAAAGCATTCCTCTTGCTCGTTTGTGGGATTTAGATGTGTTTAATGCTAAAGGCAATC
TACTGAGTCGTACAGATTTTGATCTTTCTCCAAGAACTTGTTTAGTGTGCGGAGAAAATGCAAAAATCTGTGCGAGAACC
CGCAAGCACGAGATTGATGAGATTGTAGATAAAATTCAATCTCTCGCACAGAAGCATGATTTCGCAGAACATATTGGTGA
ACAAGTTTATCTGGCATTAATACAAGAGGCTCGCTTATCGCCAAAACCTGGTTTAGTGGATGCCATCAATAACGGTTCGC
ACAAAGATATGAACCTACATACTTTTGAGCAAAGTGCGATTAGTTTAAAACCTTTTTTTACGCAGTTTGTTCTCAAAGGC
ATGATGACCGCGCATTTGTCTGAAAATCAAATTCTCGCTGAAATTCGTCCTTTAGGTTTATTAGCAGAAAAAGCAATGTT
TAAAGTTACTGATGGCGTAAACACCCACAAAGGTGCTATTTTTTCTTTTGGTTTAGTGTGTACGGCAATTGGACGATTAT
TGGCACAAAAAAGTTTGGTTCAAAGTGCGGTAGATTTTGATGTTAAATTAATCTGCTCACTTGTTGCACAATTTACTCAA
GGTTTAACGGATGAACTGAAAAATTATCCTGAACACTTGCCTAGTACGGCTGGAGTGCGTTTATTCCAAAAATATGGCTT
AACAGGTGTCCGTGGCGAAGCAGAAAATGGTTTTAATCTCATTCAAACGTTGTTGCCACAATTTGATGAGTACCATCAGT
TAGAATGGGAACATCGTTTACTGATTTTGTTGTTGAATTTAATGGCAATTAACTCCGACACTAACGTGGTTCATCGAGGT
GGTTTAGCGGGATTACATTTCATACAGCAAACAGCACAGGATCTGCTTACAGATCAACATCTTGTGACAGATAAAACAGC
ACTGACACAAGCATTAATGAAATTTGATACCGCCTGCATTGAACGTAATTTAAGTTCGGGCGGTAGTGCTGATTTATTAG
CACTAACAATTTTCTTTTTATCATTTAGAGGTAATTAA

Upstream 100 bases:

>100_bases
GAGTTGAAAGGGACTCAATTAGCTCTTTCAGCTTTCGCCAACACCCTATAAATGGAAAGCGTTAAGAAAATTTATTTTTA
TACAAAAGAGCGGTCAAATT

Downstream 100 bases:

>100_bases
TATGGCATTATCCAAAAATACAAAACTGGTGATTTTAATGGCTATCCCATTGATCACTTTCTTACTACCTGCTCCTGATG
GGCTTTCTTTGATAGCTTGG

Product: bifunctional Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase/ATP:dephospho-CoA triphosphoribosyl transferase

Products: NA

Alternate protein names: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Apo-ACP nucleodityltransferase; Holo-ACP synthase; Holo-citrate lyase synthase; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQHFFTTFSTKGSEISLEALLNAREERAILQQQLITQYGQTLLCITLTAVGGVKKNALLDYVFRKALENLTALFTQLNIT
AVKEIIRPLETGHEAYFVLPIDARTLKVLMIELEESIPLARLWDLDVFNAKGNLLSRTDFDLSPRTCLVCGENAKICART
RKHEIDEIVDKIQSLAQKHDFAEHIGEQVYLALIQEARLSPKPGLVDAINNGSHKDMNLHTFEQSAISLKPFFTQFVLKG
MMTAHLSENQILAEIRPLGLLAEKAMFKVTDGVNTHKGAIFSFGLVCTAIGRLLAQKSLVQSAVDFDVKLICSLVAQFTQ
GLTDELKNYPEHLPSTAGVRLFQKYGLTGVRGEAENGFNLIQTLLPQFDEYHQLEWEHRLLILLLNLMAINSDTNVVHRG
GLAGLHFIQQTAQDLLTDQHLVTDKTALTQALMKFDTACIERNLSSGGSADLLALTIFFLSFRGN

Sequences:

>Translated_465_residues
MQHFFTTFSTKGSEISLEALLNAREERAILQQQLITQYGQTLLCITLTAVGGVKKNALLDYVFRKALENLTALFTQLNIT
AVKEIIRPLETGHEAYFVLPIDARTLKVLMIELEESIPLARLWDLDVFNAKGNLLSRTDFDLSPRTCLVCGENAKICART
RKHEIDEIVDKIQSLAQKHDFAEHIGEQVYLALIQEARLSPKPGLVDAINNGSHKDMNLHTFEQSAISLKPFFTQFVLKG
MMTAHLSENQILAEIRPLGLLAEKAMFKVTDGVNTHKGAIFSFGLVCTAIGRLLAQKSLVQSAVDFDVKLICSLVAQFTQ
GLTDELKNYPEHLPSTAGVRLFQKYGLTGVRGEAENGFNLIQTLLPQFDEYHQLEWEHRLLILLLNLMAINSDTNVVHRG
GLAGLHFIQQTAQDLLTDQHLVTDKTALTQALMKFDTACIERNLSSGGSADLLALTIFFLSFRGN
>Mature_465_residues
MQHFFTTFSTKGSEISLEALLNAREERAILQQQLITQYGQTLLCITLTAVGGVKKNALLDYVFRKALENLTALFTQLNIT
AVKEIIRPLETGHEAYFVLPIDARTLKVLMIELEESIPLARLWDLDVFNAKGNLLSRTDFDLSPRTCLVCGENAKICART
RKHEIDEIVDKIQSLAQKHDFAEHIGEQVYLALIQEARLSPKPGLVDAINNGSHKDMNLHTFEQSAISLKPFFTQFVLKG
MMTAHLSENQILAEIRPLGLLAEKAMFKVTDGVNTHKGAIFSFGLVCTAIGRLLAQKSLVQSAVDFDVKLICSLVAQFTQ
GLTDELKNYPEHLPSTAGVRLFQKYGLTGVRGEAENGFNLIQTLLPQFDEYHQLEWEHRLLILLLNLMAINSDTNVVHRG
GLAGLHFIQQTAQDLLTDQHLVTDKTALTQALMKFDTACIERNLSSGGSADLLALTIFFLSFRGN

Specific function: Bifunctional enzyme that catalyzes formation of 2-(5''- triphosphoribosyl)-3'-dephosphocoenzyme-A, and then the transfer of this prosthetic group precursor to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield the holo-acyl carrier p

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=274, Percent_Identity=47.8102189781022, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1786831, Length=161, Percent_Identity=32.2981366459627, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR005551
- InterPro:   IPR017551 [H]

Pfam domain/function: PF01874 CitG; PF03802 CitX [H]

EC number: =2.7.7.61; =2.7.8.25 [H]

Molecular weight: Translated: 51850; Mature: 51850

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHFFTTFSTKGSEISLEALLNAREERAILQQQLITQYGQTLLCITLTAVGGVKKNALLD
CCCEEEECCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCHHHHHHH
YVFRKALENLTALFTQLNITAVKEIIRPLETGHEAYFVLPIDARTLKVLMIELEESIPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCHH
RLWDLDVFNAKGNLLSRTDFDLSPRTCLVCGENAKICARTRKHEIDEIVDKIQSLAQKHD
HEECCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAEHIGEQVYLALIQEARLSPKPGLVDAINNGSHKDMNLHTFEQSAISLKPFFTQFVLKG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
MMTAHLSENQILAEIRPLGLLAEKAMFKVTDGVNTHKGAIFSFGLVCTAIGRLLAQKSLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QSAVDFDVKLICSLVAQFTQGLTDELKNYPEHLPSTAGVRLFQKYGLTGVRGEAENGFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHH
IQTLLPQFDEYHQLEWEHRLLILLLNLMAINSDTNVVHRGGLAGLHFIQQTAQDLLTDQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCH
LVTDKTALTQALMKFDTACIERNLSSGGSADLLALTIFFLSFRGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQHFFTTFSTKGSEISLEALLNAREERAILQQQLITQYGQTLLCITLTAVGGVKKNALLD
CCCEEEECCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCHHHHHHH
YVFRKALENLTALFTQLNITAVKEIIRPLETGHEAYFVLPIDARTLKVLMIELEESIPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCHH
RLWDLDVFNAKGNLLSRTDFDLSPRTCLVCGENAKICARTRKHEIDEIVDKIQSLAQKHD
HEECCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAEHIGEQVYLALIQEARLSPKPGLVDAINNGSHKDMNLHTFEQSAISLKPFFTQFVLKG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
MMTAHLSENQILAEIRPLGLLAEKAMFKVTDGVNTHKGAIFSFGLVCTAIGRLLAQKSLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QSAVDFDVKLICSLVAQFTQGLTDELKNYPEHLPSTAGVRLFQKYGLTGVRGEAENGFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHH
IQTLLPQFDEYHQLEWEHRLLILLLNLMAINSDTNVVHRGGLAGLHFIQQTAQDLLTDQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCH
LVTDKTALTQALMKFDTACIERNLSSGGSADLLALTIFFLSFRGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]