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The map label for this gene is rspB [C]

Identifier: 148825668

GI number: 148825668

Start: 612633

End: 614675

Strand: Direct

Name: rspB [C]

Synonym: CGSHiEE_03040

Alternate gene names: 148825668

Gene position: 612633-614675 (Clockwise)

Preceding gene: 148825665

Following gene: 148825669

Centisome position: 33.79

GC content: 31.62

Gene sequence:

>2043_bases
ATGAAGGAGCGAATCAAAGCAATATGTTTAGAAAAACCAAACAATGTAGTTGTTAAAGAAGTGCCTTATCCCGAGAAAAG
TGATAATGATGTACTTATTCAGGTAGAATCAATGGGGATTTGTGGTTCTGATATTGGTGCATATAGAGGAACTAATCCAT
TAGTAACTTATCCAAGAATACTTGGGCATGAAATTGTAGGGAGAGTAATTGAAAGTGGAATTGGTATGTCAGATGGGGTA
AGGGTTGGAGAGCGAGTAATTGTTGATCCTTATGTTTTCTGTGGTCAATGCTATCCTTGTTCAATTGGTAGAACCAATTG
TTGTGAATCATTAAAGGTAATTGGTGTTCATATTGATGGAGGTATGCAGGAGGTAATTAGACATCCCGCTCATCTTTTAA
CTAAAGTCCCAGATAACCTACCGATTCATCAATTACCTTTAGCTGAACCTTTAACAATAGCTTTACACGCTTTACATAGA
ACAACTTTAAAATCAGGGGAACACATAGTAATTATTGGAGCTGGTGCAATTGGATTAATGGCTGCATTAGCAGCGGTTCA
ATATGGAGCAATCCCAATTTTAGTTGATATATTAGAACAACGTCTTGAGTATGCAAAATCCTTGGGAATTGAACATATTG
TAAATCCGCATAAGGAGGATGACATTAAAAGAATTAAGGAAATTACAAGTGGTCGTATGGCTGAAGTTGTTATGGAGGCA
TCTGGTGTTAATATTTCTATCAAAAATACTCTGCATTATGCCTCCTTTGCAGGAAGAATTGCTTTAACAGGATGGCCAAA
AACAGAAACTCCATTACCAACAAATTTAATTACCTTTAAAGAATTGAATATTTATGGTTCTAGAACAAGCAAGGGGGAAT
TTGAGGAGGCATTGGATATGCTTGCTACTAATAAAATTAATGCATCTTATATCATTACTAAGTGTATCAAATTTGAAGAA
ATTCCTAGTTTTATTTCTGATTTATCTGATCATCCAGAAAATTATTTAAAAATTAATGCAGTTTTACTAAAAAACATAAT
CAATAAGGAGAAAGTTATGAAGTCAATTAAAGGCTTAGGTAAATTATTACTTGCTTCAAGTATATTGTTTAGTAGCAGTG
CATTTGCAAAAACAATTATTAAGTTAGGACATTATAATTCTGATATTCATCCATCACATATTGCATTACAGGAATATTTT
AAGAAAACAATTGAAAATGAAACAAATCATAAATATGAGATTAGACTTTATCCTAATAATCAACTTGGCGGTGAAGATCA
AATTGTAAATGGATTACGTAATGGCACTATAGAAGCAGGTATTACAGGTTTATTATTGCAAAATGTAGATCCTATTTTTG
GAGTTTGGGAATGGCCTTATTTATTTAAGGATAATCAAGAGGCTAAAAAAGTATTGGAATCTCCAATCGCAAATAAAATT
GGTCAAAAAATGGAGAAGTATGGAATTAAATTACTTGCCTATGGTATGAATGGATTTCGTGTTATTTCATCTAATAAAAA
ATTAGAGAAATTTGACGATTTTAAAGGTTTACGTTTAAGAGTTCCGCTGAATTCACTTTTTGTTGATAGGGCTAAAGCAA
TGAATATAAATCCACAAAGCATGCCACTCAGTGAAGTTTTTACTGCATTAGAACAAAAGGTAATTGATGGTCAAGAAAAT
CCGTATATGTTAATTAAAGACTCTGGGTTATATGAAGTACAAAAATATATTATCCAAAGTAACCATATTTTCTCTCCAGG
ATTATTACAAATTAGCTTAAAAACTTGGAATAAAATTCCAAAAGAAGATCAAATTATTTTTGAAAAAGCAGCTAAATTGT
ATCAAGAGAAAGAGTGGGAATTAGCAATTAAAACAGAATTAGAAGTTAAAGATTATCTAGCTAAACATGGAAATGAAATT
ATCGTACCAAGTGAAGCATTTAAAAATGACATGGTGAATGCATCTAAGGTGCTTTATGATAGTTTTTATAAAAAATATGA
TTGGGCTAAGGATGTAGTCCAAAAAATTAACGAAGCTAAATAA

Upstream 100 bases:

>100_bases
ATATTTGGTATTCCAAAAGAGTTTTTATGTTTCATAATCATATCATAGTTAAACATAACAAGTAATTTTATTCTGTCAAT
GGCATATAAGGAGTCTAAAA

Downstream 100 bases:

>100_bases
TTAATAAGATCCCCTATGTTCAATTTTATAAATTGCTCATGGGGGATAAAGAAGGAGCTTGTTTTATGAAAATAGCAAAG
TATTTAGACAAAGCATTAGA

Product: zinc-type alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKERIKAICLEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAYRGTNPLVTYPRILGHEIVGRVIESGIGMSDGV
RVGERVIVDPYVFCGQCYPCSIGRTNCCESLKVIGVHIDGGMQEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHR
TTLKSGEHIVIIGAGAIGLMAALAAVQYGAIPILVDILEQRLEYAKSLGIEHIVNPHKEDDIKRIKEITSGRMAEVVMEA
SGVNISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDMLATNKINASYIITKCIKFEE
IPSFISDLSDHPENYLKINAVLLKNIINKEKVMKSIKGLGKLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYF
KKTIENETNHKYEIRLYPNNQLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKI
GQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDRAKAMNINPQSMPLSEVFTALEQKVIDGQEN
PYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIPKEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEI
IVPSEAFKNDMVNASKVLYDSFYKKYDWAKDVVQKINEAK

Sequences:

>Translated_680_residues
MKERIKAICLEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAYRGTNPLVTYPRILGHEIVGRVIESGIGMSDGV
RVGERVIVDPYVFCGQCYPCSIGRTNCCESLKVIGVHIDGGMQEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHR
TTLKSGEHIVIIGAGAIGLMAALAAVQYGAIPILVDILEQRLEYAKSLGIEHIVNPHKEDDIKRIKEITSGRMAEVVMEA
SGVNISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDMLATNKINASYIITKCIKFEE
IPSFISDLSDHPENYLKINAVLLKNIINKEKVMKSIKGLGKLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYF
KKTIENETNHKYEIRLYPNNQLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKI
GQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDRAKAMNINPQSMPLSEVFTALEQKVIDGQEN
PYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIPKEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEI
IVPSEAFKNDMVNASKVLYDSFYKKYDWAKDVVQKINEAK
>Mature_680_residues
MKERIKAICLEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAYRGTNPLVTYPRILGHEIVGRVIESGIGMSDGV
RVGERVIVDPYVFCGQCYPCSIGRTNCCESLKVIGVHIDGGMQEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHR
TTLKSGEHIVIIGAGAIGLMAALAAVQYGAIPILVDILEQRLEYAKSLGIEHIVNPHKEDDIKRIKEITSGRMAEVVMEA
SGVNISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDMLATNKINASYIITKCIKFEE
IPSFISDLSDHPENYLKINAVLLKNIINKEKVMKSIKGLGKLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYF
KKTIENETNHKYEIRLYPNNQLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKI
GQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDRAKAMNINPQSMPLSEVFTALEQKVIDGQEN
PYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIPKEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEI
IVPSEAFKNDMVNASKVLYDSFYKKYDWAKDVVQKINEAK

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=321, Percent_Identity=28.9719626168224, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1787863, Length=338, Percent_Identity=34.6153846153846, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI226510992, Length=308, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI1790004, Length=323, Percent_Identity=26.9349845201238, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788073, Length=258, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790045, Length=282, Percent_Identity=32.6241134751773, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1788407, Length=336, Percent_Identity=28.2738095238095, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790718, Length=298, Percent_Identity=29.1946308724832, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788075, Length=311, Percent_Identity=27.0096463022508, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786825, Length=276, Percent_Identity=28.9855072463768, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082125, Length=337, Percent_Identity=27.299703264095, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI87081918, Length=309, Percent_Identity=27.831715210356, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87082401, Length=120, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786552, Length=253, Percent_Identity=29.2490118577075, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=315, Percent_Identity=28.8888888888889, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17562878, Length=320, Percent_Identity=27.5, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71988145, Length=323, Percent_Identity=25.077399380805, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=323, Percent_Identity=26.9349845201238, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=332, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=343, Percent_Identity=32.0699708454811, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322619, Length=327, Percent_Identity=29.3577981651376, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319955, Length=327, Percent_Identity=29.0519877675841, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=358, Percent_Identity=28.4916201117318, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319257, Length=352, Percent_Identity=26.4204545454545, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=350, Percent_Identity=27.1428571428571, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=313, Percent_Identity=26.517571884984, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323980, Length=206, Percent_Identity=30.5825242718447, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=329, Percent_Identity=26.4437689969605, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=328, Percent_Identity=25.609756097561, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=148, Percent_Identity=32.4324324324324, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737897, Length=310, Percent_Identity=31.2903225806452, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17137530, Length=320, Percent_Identity=29.0625, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI221457811, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550770, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551930, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 76257; Mature: 76257

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERIKAICLEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAYRGTNPLVTYPRI
CCCHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEECHHH
LGHEIVGRVIESGIGMSDGVRVGERVIVDPYVFCGQCYPCSIGRTNCCESLKVIGVHIDG
HHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCHHHHCCEEEEEEEECC
GMQEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHRTTLKSGEHIVIIGAGAIGLM
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
AALAAVQYGAIPILVDILEQRLEYAKSLGIEHIVNPHKEDDIKRIKEITSGRMAEVVMEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHC
SGVNISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDM
CCCEEEEECCEEEHHHCCEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHH
LATNKINASYIITKCIKFEEIPSFISDLSDHPENYLKINAVLLKNIINKEKVMKSIKGLG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHH
KLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYFKKTIENETNHKYEIRLYPNN
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
QLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKI
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
GQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDRAKAMNINPQS
HHHHHHHCCEEEEECCCCEEEECCCCCHHHHCCCCCCEEECCHHHHHHHHHHHCCCCCCC
MPLSEVFTALEQKVIDGQENPYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIP
CCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCC
KEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEIIVPSEAFKNDMVNASKVLYD
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHHH
SFYKKYDWAKDVVQKINEAK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKERIKAICLEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAYRGTNPLVTYPRI
CCCHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEECHHH
LGHEIVGRVIESGIGMSDGVRVGERVIVDPYVFCGQCYPCSIGRTNCCESLKVIGVHIDG
HHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCHHHHCCEEEEEEEECC
GMQEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHRTTLKSGEHIVIIGAGAIGLM
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
AALAAVQYGAIPILVDILEQRLEYAKSLGIEHIVNPHKEDDIKRIKEITSGRMAEVVMEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHC
SGVNISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDM
CCCEEEEECCEEEHHHCCEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHH
LATNKINASYIITKCIKFEEIPSFISDLSDHPENYLKINAVLLKNIINKEKVMKSIKGLG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHHHHHHH
KLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYFKKTIENETNHKYEIRLYPNN
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
QLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKI
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
GQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDRAKAMNINPQS
HHHHHHHCCEEEEECCCCEEEECCCCCHHHHCCCCCCEEECCHHHHHHHHHHHCCCCCCC
MPLSEVFTALEQKVIDGQENPYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIP
CCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCC
KEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEIIVPSEAFKNDMVNASKVLYD
CCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHHH
SFYKKYDWAKDVVQKINEAK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]