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The map label for this gene is gmhB [H]

Identifier: 148825518

GI number: 148825518

Start: 408650

End: 409204

Strand: Direct

Name: gmhB [H]

Synonym: CGSHiEE_02095

Alternate gene names: 148825518

Gene position: 408650-409204 (Clockwise)

Preceding gene: 148825514

Following gene: 148825519

Centisome position: 22.54

GC content: 36.76

Gene sequence:

>555_bases
ATGAATAAGGCTATTTTTTTAGATCGCGATGGCACGTTAAATATTGATTATGGTTATGTACACGAAATTGATAACTTTAA
ATTTATTGATGGTGCGATTGATGCATTGCGAGAATTAAAGAAAATGGGATATATGTTGGTATTAGTGACCAACCAGTCGG
GCATTGCACGTGGTTATTTTTCTGAGGAGCAGTTTTTACAATTAACAGAATGGATGGATTGGTCGTTAGCTGAACAAGAT
GTGGATTTGGATGGTATTTACTATTGTCCACATCATCCTGAGGGAAAGGGCGAATATAAAGAAGATTGTGATTGTCGGAA
GCCTAAATCGGGAATGTTATTGCAAGCGATCAAAGAATTAAAGATCGATCCTACGCAATCTATTATGGTTGGAGATAAAG
TTGAAGACCTAAAAGCGGGGATTGGTGCGAAAGTAAAAATGAACGTATTAGTTCGTACTGGTAAACCAGTAACAGGGGAA
GGAGAAGGAATAGCGGATTATGTGTTAGATTCTATCGTAGATCTTCCGAGAATTTTAAAACGCTTAAAAAAATAG

Upstream 100 bases:

>100_bases
GATTATCTTTTTTAGACAGATTAGTTATGACTTATATTTGCTAATTGCTTGGATTAAATAGATAATTTTCGTCAATTTGA
CATGTATAAAAGGTTAGAGA

Downstream 100 bases:

>100_bases
CCAAAAAGATCTATATTTTGCTCTAATCGCTTGCACTTTAATCAAAAGATCATTTTTTTAAATATTTTTACAAAAAAGTA
CTTGCAAGGGATTTGAAAAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEEQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHPEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK

Sequences:

>Translated_184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEEQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHPEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK
>Mature_184_residues
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYFSEEQFLQLTEWMDWSLAEQD
VDLDGIYYCPHHPEGKGEYKEDCDCRKPKSGMLLQAIKELKIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGE
GEGIADYVLDSIVDLPRILKRLKK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=182, Percent_Identity=67.032967032967, Blast_Score=263, Evalue=4e-72,
Organism=Escherichia coli, GI87082027, Length=140, Percent_Identity=33.5714285714286, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20806; Mature: 20806

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYF
CCCCEEEECCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
SEEQFLQLTEWMDWSLAEQDVDLDGIYYCPHHPEGKGEYKEDCDCRKPKSGMLLQAIKEL
CHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGEGEGIADYVLDSIVDLPRILK
CCCCCCCEEECCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKK
HHCC
>Mature Secondary Structure
MNKAIFLDRDGTLNIDYGYVHEIDNFKFIDGAIDALRELKKMGYMLVLVTNQSGIARGYF
CCCCEEEECCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
SEEQFLQLTEWMDWSLAEQDVDLDGIYYCPHHPEGKGEYKEDCDCRKPKSGMLLQAIKEL
CHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KIDPTQSIMVGDKVEDLKAGIGAKVKMNVLVRTGKPVTGEGEGIADYVLDSIVDLPRILK
CCCCCCCEEECCCHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RLKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12101286 [H]