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The map label for this gene is yggV [C]

Identifier: 148825461

GI number: 148825461

Start: 334534

End: 335121

Strand: Direct

Name: yggV [C]

Synonym: CGSHiEE_01765

Alternate gene names: 148825461

Gene position: 334534-335121 (Clockwise)

Preceding gene: 148825460

Following gene: 148825462

Centisome position: 18.45

GC content: 39.63

Gene sequence:

>588_bases
ATGAAACAAAAAATCGTACTTGCTACAGGCAATAAAGGAAAAGTAAAAGAAATGGCTGATGTCCTATCTGATTTTGGTTT
TGAAGTGATTGCGCAAACAGATCTAGGCATTGAAAGCCCAGAAGAAACTGGCTTAACTTTCGTTGAAAATGCCTTATTAA
AAGCACGCTATGCCTCAGAGAAATCAGGTTTGCCTGCTATTGCGGATGATTCTGGCTTAGTAGTTTCCGCACTTAATGGC
GCACCAGGTCTGTATTCTGCCCGTTATGCTGGTGAAGAGGGCAATGATGCTAAAAACCGTGAGAAATTATTGGCAGAGCT
TGCACATATTGCACAAGATCAACGCCAAGCCAAATTTGTGAGCTGTATCGTGTTTTTACAGCATCCAACAGATCCATCGC
CAATTATTGCCGAAGGCGAGTGTTGTGGTGTGATTGGTTTTGAAGAAAAAGGCGAAAATGGTTTTGGTTATGACAGTTTA
TTCTTTAGTCCAGAACAAGGTTGCACATTTGCTGAATTAGAAACAGCTGAGAAGAAAAAAATTTCTCATCGAGCAAAGGC
ATTGAGCGTTTTAAAAAATAAATTATAA

Upstream 100 bases:

>100_bases
AACGTTCCTTCGAAAAAGAAGTTGGACGAATGAATATTCAATTTACCGAGCAAAACTGGGCTGATTTAATGGCGGCTTAT
CATCAATAAAAGGATTGATT

Downstream 100 bases:

>100_bases
AGTTAATAAAATTATTTAATCTATCAATAAAAAATAACCCTAAAAATAATAATTCACATGTTAATCAGAGATAATTTTAT
AACAGACAGACAGACAGACA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASEKSGLPAIADDSGLVVSALNG
APGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSL
FFSPEQGCTFAELETAEKKKISHRAKALSVLKNKL

Sequences:

>Translated_195_residues
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASEKSGLPAIADDSGLVVSALNG
APGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSL
FFSPEQGCTFAELETAEKKKISHRAKALSVLKNKL
>Mature_195_residues
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASEKSGLPAIADDSGLVVSALNG
APGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSL
FFSPEQGCTFAELETAEKKKISHRAKALSVLKNKL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=56.9948186528497, Blast_Score=234, Evalue=2e-63,
Organism=Drosophila melanogaster, GI19920712, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20985; Mature: 20985

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASE
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHH
KSGLPAIADDSGLVVSALNGAPGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFV
CCCCCEEECCCCEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSLFFSPEQGCTFAELETAEKKK
HHEEEEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
ISHRAKALSVLKNKL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASE
CCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHH
KSGLPAIADDSGLVVSALNGAPGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFV
CCCCCEEECCCCEEEEECCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSLFFSPEQGCTFAELETAEKKK
HHEEEEECCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
ISHRAKALSVLKNKL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]