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The map label for this gene is sdaC [H]

Identifier: 148825433

GI number: 148825433

Start: 299124

End: 300362

Strand: Direct

Name: sdaC [H]

Synonym: CGSHiEE_01615

Alternate gene names: 148825433

Gene position: 299124-300362 (Clockwise)

Preceding gene: 148825432

Following gene: 148825434

Centisome position: 16.5

GC content: 36.8

Gene sequence:

>1239_bases
ATGAAATCAACAGAAAAACTCAAATGGAACAAATTTGATGCAACATGGATGTTAAACCTTTTCGGTACGGCGGTTGGCGC
GGGCGTATTGTTCTTGCCGATTAACGCAGGGATGGGTGGATTTTGGCCGTTAGTTTTAATGGCAATTATCGTCGGGCCAA
TGACTTATTTTGCTCACCGTGGCTTAGCCTACTTTGTACTTTCATCAAAAAATCCTGGCAGCGATATTACTGAAGTAGTG
GAAGAACACTTTGGTAAAACAGCGGGTAAACTTATTACCTTACTTTATTTTTTCGCGATTTTCCCTATTCTGTTGATTTA
CGGTAACGGTATTACTAACACCGTAGATTCTTTTATTGTAAATCAACTTGGTATGGCATCACCAAATCGAGTCATTCTCT
CTTTTGTATTAATTGCGGTATTGATTTCCGTGATGTTATTTAATGAAAAAGTGATGTTAAAAATCACAGAATGGCTTGTT
TATCCATTAGTCTTAATTTTATTTGTTCTTTCTATTTACTTAATTCCTGAATGGAATAGTGCCGTATTATATGAACTTCC
AACAGCAGGCGGTTTCTTAACAACTTTATGGCTAACCATTCCCGTATTAGTATTTTCATTTAACCATTCACCAGCAATTT
CATCTTTCACTTGCTCACAATTCCGTGAATACAAAACGTTTGAGGGTGCAGAACGCCATATCAGCCATACAGAAAAAGGC
GCCTCAACGATTTTGTTATTCTTTGTAATGTTCTTCGTATTTAGCTGTGTATTAACATTAACACCTGAAGAATTAGTGGC
AGCAAAAGAACAGAATATTAGTATCTTGTCTTTCTTAGCGAATAAATTTGATAATCCATATATCTCTTATTTTGGCCCGC
TTGTTGCATTCTTAGCGATTACTAGTTCATTCTTCGGTCACTATATGGGGGCGCGTGAAGGCTTAGAGGGTTTATATTTA
AAAATGAAAGGTGAAGCAGTAAATCGTAAAAAACTCAATTATGCGACCGCACTTTTCTTCTTATTAACGTTATGGGGCGT
TGCGATTATTAATCCAAGTATCTTAGGCTTAATCGAATCTCTTGGCGGCCCAATCATTGCGATGATTTTGTTTATCATGC
CAATGTACGCGATTCGAAAAATCCCAGCAATGAAACGCTACAGCGGACGTTTCAGTAATGTATTTGTAACAATTATGGGG
CTAATTGCTATTTCTGCAGTTGTTTATGGATTATTATAA

Upstream 100 bases:

>100_bases
ATTCTCTATTTATCGGCATAACATAATACTCAAATTTTGTTAGGGCATATTTTGCTCTACAAATTGACAAATTTAAGTAA
TTTATGCTTTGGAGCAAACT

Downstream 100 bases:

>100_bases
TCGCCTTTAATTTTAACGAATTTTGAGAAATTTATGATTAGCGTATTTGATATGTTTAAGGTGGGAATTGGGCCATCCAG
TTCCCACACGGTCGGTCCGA

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVV
EEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLV
YPLVLILFVLSIYLIPEWNSAVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFEGAERHISHTEKG
ASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYL
KMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMG
LIAISAVVYGLL

Sequences:

>Translated_412_residues
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVV
EEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLV
YPLVLILFVLSIYLIPEWNSAVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFEGAERHISHTEKG
ASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYL
KMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMG
LIAISAVVYGLL
>Mature_412_residues
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVV
EEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLV
YPLVLILFVLSIYLIPEWNSAVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFEGAERHISHTEKG
ASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYL
KMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMG
LIAISAVVYGLL

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=416, Percent_Identity=59.375, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1789504, Length=433, Percent_Identity=46.4203233256351, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1789211, Length=404, Percent_Identity=36.1386138613861, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI145693183, Length=396, Percent_Identity=26.5151515151515, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789961, Length=396, Percent_Identity=26.010101010101, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 45847; Mature: 45847

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GLAYFVLSSKNPGSDITEVVEEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIV
CEEEEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLVYPLVLILFVLSIYLIPEWNS
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFEGAERHISHTEKG
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
ASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TSSFFGHYMGAREGLEGLYLKMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIES
HHHHHHHHHHHHHCCCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMGLIAISAVVYGLL
HCCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GLAYFVLSSKNPGSDITEVVEEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIV
CEEEEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLVYPLVLILFVLSIYLIPEWNS
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVLYELPTAGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFEGAERHISHTEKG
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
ASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TSSFFGHYMGAREGLEGLYLKMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIES
HHHHHHHHHHHHHCCCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMGLIAISAVVYGLL
HCCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]