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The map label for this gene is hetN [H]

Identifier: 148824368

GI number: 148824368

Start: 3555261

End: 3555968

Strand: Direct

Name: hetN [H]

Synonym: TBFG_13195

Alternate gene names: 148824368

Gene position: 3555261-3555968 (Clockwise)

Preceding gene: 148824364

Following gene: 148824369

Centisome position: 80.36

GC content: 64.97

Gene sequence:

>708_bases
ATGACTTCACTAGCCGAGCGGACCGTGCTCGTCACCGGCGCCAACCGCGGCATGGGCCGCGAATACGTCGCTCAGCTTCT
CGGTCGCAAAGTGGCAAAGGTCTATGCCGCTACCCGCAACCCGCTGGCAATCGACGTTAGCGATCCGCGCGTGATTCCGC
TCCAACTCGACGTCACCGACGCGGTGTCGGTCGCCGAGGCAGCCGACTTAGCAACCGATGTCGGCATTCTGATCAACAAT
GCCGGCATCTCCCGGGCGTCCTCGGTGCTCGACAAGGACACATCCGCGCTTCGCGGCGAGCTGGAGACGAACCTGTTCGG
ACCGCTCGCGCTGGCCTCCGCGTTCGCCGACCGCATCGCCGAGAGATCCGGTGCCATCGTCAACGTTTCCTCGGTACTCG
CCTGGCTTCCCCTTGGCATGAGCTATGGAGTGTCCAAGGCGGCGATGTGGAGCGCGACGGAGTCGATGCGTATCGAGCTG
GCGCCGCGCGGTGTGCAGGTGGTGGGCGTCTACGTGGGGCTGGTCGACACCGACATGGGTCGATTCGCCGACGCGCCGAA
GTCCGATCCTGCCGATGTGGTCCGCCAGGTGCTCGACGGAATAGAGGCTGGCAAGGAGGACGTGCTGGCCGACGAGATGA
GCCGTCAGGTGCGCGCGTCGCTGAATGTCCCTGCGCGGGAACGTATCGCGCGGTTGATGGGTAACTGA

Upstream 100 bases:

>100_bases
GGCGGCATAGTGCTGAGTATACCGACCTGTTTACAACACCCCTTAGCGCGTGTACCGTCAAAGCACAAAGTACACCAATC
GGTTTACTGTAGGAGGTCTC

Downstream 100 bases:

>100_bases
GTCCGAAAGTCGATATGGCCATGTCCGCCAAGGCCTCAGACGATATTGCCTGGCTACCGGCGACCGCTCAACTCGCGGTG
CTCGCCGCCAAGAAGGTGTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTDAVSVAEAADLATDVGILINN
AGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSGAIVNVSSVLAWLPLGMSYGVSKAAMWSATESMRIEL
APRGVQVVGVYVGLVDTDMGRFADAPKSDPADVVRQVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN

Sequences:

>Translated_235_residues
MTSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTDAVSVAEAADLATDVGILINN
AGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSGAIVNVSSVLAWLPLGMSYGVSKAAMWSATESMRIEL
APRGVQVVGVYVGLVDTDMGRFADAPKSDPADVVRQVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN
>Mature_234_residues
TSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTDAVSVAEAADLATDVGILINNA
GISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSGAIVNVSSVLAWLPLGMSYGVSKAAMWSATESMRIELA
PRGVQVVGVYVGLVDTDMGRFADAPKSDPADVVRQVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN

Specific function: May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=238, Percent_Identity=28.9915966386555, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI119392083, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=31.7948717948718, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI7705925, Length=209, Percent_Identity=32.0574162679426, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=206, Percent_Identity=31.0679611650485, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=31.7204301075269, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=216, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI72001658, Length=209, Percent_Identity=32.0574162679426, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=210, Percent_Identity=30.952380952381, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=240, Percent_Identity=29.5833333333333, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=241, Percent_Identity=28.6307053941909, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=33.8624338624339, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=31.6326530612245, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24643142, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=212, Percent_Identity=33.4905660377358, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=32, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640547, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24850; Mature: 24719

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTD
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCHH
AVSVAEAADLATDVGILINNAGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIA
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ERSGAIVNVSSVLAWLPLGMSYGVSKAAMWSATESMRIELAPRGVQVVGVYVGLVDTDMG
HHCCCEEEHHHHHHHHHCCHHCCCCHHHHHHCCCCEEEEECCCCEEEEEEEEEHHCCCHH
RFADAPKSDPADVVRQVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TSLAERTVLVTGANRGMGREYVAQLLGRKVAKVYAATRNPLAIDVSDPRVIPLQLDVTD
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCHH
AVSVAEAADLATDVGILINNAGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIA
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ERSGAIVNVSSVLAWLPLGMSYGVSKAAMWSATESMRIELAPRGVQVVGVYVGLVDTDMG
HHCCCEEEHHHHHHHHHCCHHCCCCHHHHHHCCCCEEEEECCCCEEEEEEEEEHHCCCHH
RFADAPKSDPADVVRQVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840 [H]