Click here to switch to the map view.

The map label for this gene is aofH

Identifier: 148824364

GI number: 148824364

Start: 3551610

End: 3552974

Strand: Direct

Name: aofH

Synonym: TBFG_13191

Alternate gene names: 148824364

Gene position: 3551610-3552974 (Clockwise)

Preceding gene: 148824363

Following gene: 148824368

Centisome position: 80.27

GC content: 68.28

Gene sequence:

>1365_bases
ATGCGGTTGACTAGAGCGGTGACAAACCCACCGTGGACTGTCGATGTTGTCGTGGTGGGCGCGGGCTTCGCCGGGCTGGC
CGCGGCCCGCGAGCTGACGCGACAGGGTCACGAGGTGCTGGTGTTCGAAGGCCGCGATCGGGTGGGCGGCCGCTCGTTAA
CCGGTCGCGTGGCAGGGGTGCCCGCGGATATGGGCGGCTCGTTCATCGGCCCGACCCAAGACGCCGTGCTGGCGTTGGCC
ACCGAGCTGGGGATCCCGACAACCCCGACCCACCGCGACGGCCGAAACGTCATCCAGTGGCGGGGATCGGCACGCAGCTA
TCGTGGCACCATCCCCAAGCTGTCGCTGACCGGGCTCATCGACATCGGCCGGTTGCGTTGGCAATTCGAGCGAATTGCCC
GCGGCGTTCCGGTGGCCGCCCCCTGGGATGCGCGGCGCGCGCGTGAACTCGACGACGTGTCGCTCGGGGAGTGGTTGCGC
TTGGTGCGCGCCACATCGTCCTCGCGGAACCTGATGGCCATCATGACCCGGGTGACCTGGGGTTGTGAGCCCGACGATGT
CTCGATGCTGCACGCCGCCCGCTACGTACGCGCGGCCGGCGGCCTGGACCGGCTGCTCGACGTCAAAAATGGTGCCCAGC
AGGACCGTGTGCCGGGGGGGACACAGCAGATCGCCCAGGCGGCCGCCGCCCAACTCGGCGCACGCGTCCTGCTCAACGCC
GCGGTGCGTCGCATCGACCGGCACGGAGCGGGTGTGACGGTCACGTCCGATCAGGGTCAGGCCGAGGCCGGGTTCGTCAT
CGTCGCCATTCCACCGGCCCATCGCGTGGCCATCGAGTTCGATCCCCCGCTGCCGCCGGAATATCAGCAGCTCGCCCACC
ATTGGCCGCAGGGCCGGCTGAGCAAGGCCTACGCGGCCTATTCGACGCCGTTCTGGCGGGCCAGCGGGTATTCCGGCCAG
GCGCTGTCCGATGAGGCGCCGGTGTTCATCACCTTCGACGTCAGTCCGCACGCCGACGGGCCAGGCATTCTGATGGGGTT
CGTCGATGCTCGCGGGTTCGACTCGCTACCCATCGAAGAGCGCCGCCGCGATGCATTGCGCTGCTTTGCGTCGCTGTTCG
GCGACGAAGCGCTCGACCCCCTTGATTATGTTGACTATCGTTGGGGTACAGAGGAATTCGCGCCGGGTGGTCCGACCGCG
GCGGTACCGCCGGGGTCGTGGACGAAATACGGTCACTGGTTACGTGAGCCGGTCGGTCCGATTCACTGGGCGAGCACTGA
GACCGCGGACGAATGGACCGGGTATTTCGACGGCGCCGTCAGATCCGGTCAGCGTGCCGCCGCCGAGGTCGCCGCCCTGC
TATGA

Upstream 100 bases:

>100_bases
GGTGAGGCTATCCGCATTCGCGAGTCCAGGGTTCCTGGGCGCCGGCCGGGAAACGGCCCGAAAACGACGGCAGCCGGAAT
AGCCGACCGGAACCGCCGAA

Downstream 100 bases:

>100_bases
GCTGATCCGCCGGTCCCGGACGTGCCGGGTCACCGATTCGGCCAGCGCCCGCAGGTGGCTGTTCACCTCTTGGTGCCGTT
CCAGCATCGAGCAGTGGCCG

Product: flavin-containing monoamine oxidase aofH

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALA
TELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLR
LVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNA
AVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQ
ALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTA
AVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL

Sequences:

>Translated_454_residues
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALA
TELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLR
LVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNA
AVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQ
ALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTA
AVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
>Mature_454_residues
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGVPADMGGSFIGPTQDAVLALA
TELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLIDIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLR
LVRATSSSRNLMAIMTRVTWGCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNA
AVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGYSGQ
ALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEERRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTA
AVPPGSWTKYGHWLREPVGPIHWASTETADEWTGYFDGAVRSGQRAAAEVAALL

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family

Homologues:

Organism=Homo sapiens, GI4557735, Length=446, Percent_Identity=36.7713004484305, Blast_Score=281, Evalue=8e-76,
Organism=Homo sapiens, GI38202207, Length=437, Percent_Identity=36.3844393592677, Blast_Score=265, Evalue=9e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AOFH_MYCBO (P63534)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_856840.1
- ProteinModelPortal:   P63534
- SMR:   P63534
- EnsemblBacteria:   EBMYCT00000016770
- GeneID:   1093212
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3195
- GeneTree:   EBGT00050000016545
- HOGENOM:   HBG556224
- ProtClustDB:   CLSK792319
- BioCyc:   MBOV233413:MB3195-MONOMER
- InterPro:   IPR001613
- InterPro:   IPR002937
- PRINTS:   PR00757

Pfam domain/function: PF01593 Amino_oxidase

EC number: 1.4.3.4

Molecular weight: Translated: 49137; Mature: 49137

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGV
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECC
PADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLI
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCEE
DIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTW
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHC
GCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRL
HHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHH
SKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEE
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCHHH
RRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGP
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
EEECCCCCHHHHCCHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MRLTRAVTNPPWTVDVVVVGAGFAGLAAARELTRQGHEVLVFEGRDRVGGRSLTGRVAGV
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECC
PADMGGSFIGPTQDAVLALATELGIPTTPTHRDGRNVIQWRGSARSYRGTIPKLSLTGLI
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCEE
DIGRLRWQFERIARGVPVAAPWDARRARELDDVSLGEWLRLVRATSSSRNLMAIMTRVTW
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHC
GCEPDDVSMLHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLGARVLLNA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVRRIDRHGAGVTVTSDQGQAEAGFVIVAIPPAHRVAIEFDPPLPPEYQQLAHHWPQGRL
HHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHH
SKAYAAYSTPFWRASGYSGQALSDEAPVFITFDVSPHADGPGILMGFVDARGFDSLPIEE
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCHHH
RRRDALRCFASLFGDEALDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGP
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IHWASTETADEWTGYFDGAVRSGQRAAAEVAALL
EEECCCCCHHHHCCHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972