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The map label for this gene is pyc [H]

Identifier: 148824157

GI number: 148824157

Start: 3331136

End: 3334519

Strand: Reverse

Name: pyc [H]

Synonym: TBFG_12982

Alternate gene names: 148824157

Gene position: 3334519-3331136 (Counterclockwise)

Preceding gene: 148824158

Following gene: 148824156

Centisome position: 75.37

GC content: 65.28

Gene sequence:

>3384_bases
GTGTTTTCCAAGGTGCTCGTCGCCAATCGCGGGGAGATCGCGATCCGGGCCTTTCGTGCCGCCTACGAACTGGGCGTCGG
AACCGTGGCCGTTTATCCGTACGAGGACCGCAATTCGCAGCACCGTCTCAAGGCGGACGAGTCTTACCAGATCGGCGACA
TCGGTCACCCGGTGCATGCATACCTGTCGGTCGACGAGATCGTCGCGACGGCCCGTCGGGCGGGTGCCGACGCTATCTAC
CCTGGCTACGGGTTTCTATCGGAGAATCCGGATCTGGCTGCGGCATGCGCGGCGGCGGGCATCAGCTTCGTCGGTCCCAG
CGCCGAAGTGCTTGAGCTGGCTGGGAATAAGTCTCGCGCCATCGCGGCGGCCCGCGAAGCCGGCTTGCCCGTGCTGATGT
CCTCGGCGCCGTCGGCCTCGGTCGACGAACTGCTGTCGGTTGCGGCCGGCATGCCGTTTCCGTTGTTCGTCAAGGCAGTT
GCCGGTGGCGGGGGCCGGGGTATGCGTCGTGTCGGCGATATCGCGGCGCTTCCGGAGGCGATCGAAGCCGCCAGCCGGGA
AGCCGAGTCGGCGTTCGGGGACCCGACGGTCTATCTCGAGCAGGCAGTGATCAATCCACGCCACATCGAGGTGCAGATTC
TGGCGGACAACCTCGGCGACGTGATCCATCTCTATGAGCGTGACTGCAGTGTGCAGCGTCGCCATCAGAAGGTCATCGAG
CTGGCGCCCGCGCCGCACCTGGACGCCGAGTTGCGTTACAAGATGTGCGTCGATGCGGTCGCCTTCGCCCGCCATATCGG
GTACAGCTGCGCGGGCACCGTCGAGTTCCTGCTGGACGAGCGAGGGGAGTATGTCTTCATCGAGATGAATCCGCGGGTTC
AGGTGGAGCACACGGTGACCGAGGAGATTACCGACGTCGACCTGGTCGCCAGCCAGCTGCGCATTGCCGCCGGGGAGACG
CTCGAACAATTGGGCCTGCGGCAGGAGGACATCGCACCGCATGGCGCCGCACTACAGTGCCGGATCACCACCGAGGATCC
GGCCAACGGCTTCCGGCCGGACACGGGCCGGATCAGCGCGTTGCGCACCGCCGGCGGTGCCGGTGTCCGCCTGGACGGCA
GCACCAACCTGGGCGCAGAAATCAGCCCGTACTTCGACTCCATGCTGGTCAAGCTGACCTGTCGGGGCCGTGACCTCCCT
ACCGCAGTGAGCCGTGCGCGCCGGGCGATCGCGGAGTTCCGGATCCGCGGGGTATCGACGAATATTCCGTTCCTGCAAGC
GGTCCTGGATGACCCGGACTTCCGAGCGGGCCGGGTCACCACGTCCTTCATTGATGAGCGGCCGCAGCTGCTGACCGCGC
GCGCCTCGGCCGACCGCGGCACCAAGATCCTTAACTTCCTGGCCGATGTCACCGTCAACAACCCGTATGGCTCGCGTCCG
TCAACGATCTACCCGGACGACAAGCTGCCCGATCTTGATCTGCGGGCCGCACCACCGGCCGGGTCCAAGCAGCGACTAGT
CAAGTTGGGGCCGGAAGGATTTGCTCGTTGGCTGCGGGAGTCGGCCGCGGTCGGGGTCACCGATACCACATTCCGGGATG
CTCACCAGTCGTTACTGGCTACCCGAGTACGCACCAGCGGACTGTCGCGGGTGGCACCGTATCTCGCGCGGACCATGCCG
CAGCTGTTGTCCGTGGAGTGTTGGGGCGGTGCGACTTACGATGTGGCGCTGCGCTTTCTCAAGGAGGATCCCTGGGAACG
GCTGGCCACACTGCGTGCAGCAATGCCCAATATCTGCTTGCAGATGCTATTGCGGGGCCGCAATACCGTGGGCTACACGC
CGTACCCGGAAATCGTGACGTCGGCGTTTGTGCAAGAAGCAACAGCCACCGGTATCGACATCTTTCGTATCTTCGACGCG
CTCAACAACATCGAGTCGATGCGTCCGGCGATCGACGCAGTACGCGAAACAGGTTCTGCGATAGCAGAAGTCGCGATGTG
CTACACGGGCGACCTTACCGATCCGGGTGAACAGCTGTACACGCTGGACTACTACCTGAAACTGGCTGAGCAGATCGTGG
ACGCCGGCGCCCATGTGCTGGCGATCAAGGATATGGCTGGACTGTTGCGCCCGCCGGCCGCTCAAAGGTTGGTCAGCGCC
CTGCGCAGTCGCTTCGACCTGCCCGTTCACCTGCACACCCACGACACACCGGGTGGCCAGCTCGCCAGCTATGTGGCCGC
TTGGCACGCCGGGGCCGATGCCGTCGACGGCGCCGCCGCGCCGCTGGCGGGAACGACCAGCCAGCCCGCGCTGAGCTCGA
TCGTTGCTGCCGCTGCCCACACCGAGTACGACACCGGCCTGTCGCTTTCGGCGGTGTGCGCCCTGGAGCCGTACTGGGAG
GCGTTACGAAAAGTGTATGCGCCGTTCGAGTCTGGGTTGCCGGGGCCGACGGGGCGGGTTTATCACCACGAGATTCCGGG
CGGCCAACTGTCCAATCTGCGCCAGCAAGCAATTGCTCTTGGTCTGGGAGATCGATTCGAAGAGATCGAAGAGGCCTACG
CGGGCGCCGACCGAGTGTTGGGCAGGCTGGTTAAGGTCACGCCAACGTCCAAGGTGGTCGGCGATCTGGCGCTGGCACTG
GTCGGCGCCGGTGTCAGTGCAGACGAATTCGCCTCCGATCCAGCGCGATTTGGCATCCCGGAATCGGTACTCGGATTTCT
GCGGGGCGAGCTGGGTGATCCGCCCGGCGGGTGGCCCGAACCGCTGCGCACTGCGGCGCTGGCCGGTCGCGGGGCGGCCA
GGCCCACTGCGCAATTGGCGGCGGACGACGAGATTGCCCTATCGTCGGTCGGAGCCAAGCGTCAGGCCACCCTGAACAGG
CTGTTATTTCCCAGTCCAACAAAGGAATTCAATGAGCACCGGGAAGCCTACGGCGACACGTCGCAATTGTCGGCCAACCA
GTTCTTCTATGGTCTGCGCCAAGGTGAAGAGCATCGGGTGAAGCTGGAGCGTGGGGTGGAGCTGTTGATCGGGCTGGAGG
CCATTTCCGAACCCGACGAACGCGGCATGCGAACGGTGATGTGCATCCTCAACGGGCAGCTGCGGCCGGTGCTAGTGCGC
GACCGCAGCATTGCCAGTGCCGTTCCGGCCGCCGAGAAGGCCGACCGCGGCAATCCCGGACACATCGCCGCGCCATTTGC
CGGAGTCGTCACGGTCGGGGTGTGCGTCGGCGAGCGGGTCGGCGCCGGCCAAACCATCGCCACCATCGAGGCGATGAAGA
TGGAAGCCCCGATCACCGCCCCGGTTGCCGGCACCGTGGAGCGGGTGGCGGTGTCGGACACCGCCCAGGTGGAGGGCGGA
GACCTGTTGGTGGTGGTGAGCTGA

Upstream 100 bases:

>100_bases
GGCCACGCTCTGGTTCACGACAGTATTCCTGCTGATCATGGTCCGCTTTTGGGACTATTGGTCGACGCTGATCTGAGACA
TCCGGATAAGGGAGCCACAC

Downstream 100 bases:

>100_bases
CCGCCCCGGCGACGATGCAGTGGGGGTACCGCCTGCTTGCGGGGGACGAAGCGATGAGGTGGGGGTACCGCCCGCTTGCG
GAGGAGCGGCGCAGATGAGC

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1127; Mature: 1127

Protein sequence:

>1127_residues
MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQIGDIGHPVHAYLSVDEIVATARRAGADAIY
PGYGFLSENPDLAAACAAAGISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAV
AGGGGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIE
LAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVTEEITDVDLVASQLRIAAGET
LEQLGLRQEDIAPHGAALQCRITTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLP
TAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRP
STIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATRVRTSGLSRVAPYLARTMP
QLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDA
LNNIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVLAIKDMAGLLRPPAAQRLVSA
LRSRFDLPVHLHTHDTPGGQLASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSAVCALEPYWE
ALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALAL
VGAGVSADEFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIALSSVGAKRQATLNR
LLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVR
DRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEAPITAPVAGTVERVAVSDTAQVEGG
DLLVVVS

Sequences:

>Translated_1127_residues
MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQIGDIGHPVHAYLSVDEIVATARRAGADAIY
PGYGFLSENPDLAAACAAAGISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAV
AGGGGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIE
LAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVTEEITDVDLVASQLRIAAGET
LEQLGLRQEDIAPHGAALQCRITTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLP
TAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRP
STIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATRVRTSGLSRVAPYLARTMP
QLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDA
LNNIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVLAIKDMAGLLRPPAAQRLVSA
LRSRFDLPVHLHTHDTPGGQLASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSAVCALEPYWE
ALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALAL
VGAGVSADEFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIALSSVGAKRQATLNR
LLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVR
DRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEAPITAPVAGTVERVAVSDTAQVEGG
DLLVVVS
>Mature_1127_residues
MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQIGDIGHPVHAYLSVDEIVATARRAGADAIY
PGYGFLSENPDLAAACAAAGISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAV
AGGGGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIE
LAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVTEEITDVDLVASQLRIAAGET
LEQLGLRQEDIAPHGAALQCRITTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLP
TAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRP
STIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATRVRTSGLSRVAPYLARTMP
QLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDA
LNNIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVLAIKDMAGLLRPPAAQRLVSA
LRSRFDLPVHLHTHDTPGGQLASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSAVCALEPYWE
ALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALAL
VGAGVSADEFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIALSSVGAKRQATLNR
LLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVR
DRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEAPITAPVAGTVERVAVSDTAQVEGG
DLLVVVS

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1142, Percent_Identity=47.3730297723292, Blast_Score=1005, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1142, Percent_Identity=47.3730297723292, Blast_Score=1005, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1142, Percent_Identity=47.3730297723292, Blast_Score=1005, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=461, Percent_Identity=43.6008676789588, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI65506442, Length=448, Percent_Identity=40.4017857142857, Blast_Score=314, Evalue=3e-85,
Organism=Homo sapiens, GI189095269, Length=448, Percent_Identity=40.4017857142857, Blast_Score=314, Evalue=3e-85,
Organism=Homo sapiens, GI295821183, Length=448, Percent_Identity=40.4017857142857, Blast_Score=313, Evalue=4e-85,
Organism=Homo sapiens, GI38679960, Length=543, Percent_Identity=30.939226519337, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679974, Length=543, Percent_Identity=30.939226519337, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679971, Length=543, Percent_Identity=30.939226519337, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679977, Length=543, Percent_Identity=30.939226519337, Blast_Score=225, Evalue=2e-58,
Organism=Homo sapiens, GI38679967, Length=543, Percent_Identity=30.939226519337, Blast_Score=225, Evalue=2e-58,
Organism=Homo sapiens, GI134142062, Length=503, Percent_Identity=30.4174950298211, Blast_Score=215, Evalue=2e-55,
Organism=Escherichia coli, GI1789654, Length=456, Percent_Identity=44.7368421052632, Blast_Score=352, Evalue=5e-98,
Organism=Caenorhabditis elegans, GI17562816, Length=1145, Percent_Identity=46.7248908296943, Blast_Score=1003, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=456, Percent_Identity=44.078947368421, Blast_Score=351, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17567343, Length=450, Percent_Identity=40.8888888888889, Blast_Score=315, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI133931226, Length=486, Percent_Identity=30.6584362139918, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71997163, Length=443, Percent_Identity=30.9255079006772, Blast_Score=208, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71997168, Length=443, Percent_Identity=30.9255079006772, Blast_Score=207, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1152, Percent_Identity=45.7465277777778, Blast_Score=976, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1152, Percent_Identity=46.3541666666667, Blast_Score=974, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=38.716814159292, Blast_Score=327, Evalue=8e-90,
Organism=Saccharomyces cerevisiae, GI6324343, Length=525, Percent_Identity=31.047619047619, Blast_Score=214, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6323863, Length=468, Percent_Identity=31.6239316239316, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24652212, Length=1140, Percent_Identity=46.9298245614035, Blast_Score=1008, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1140, Percent_Identity=46.9298245614035, Blast_Score=1008, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1140, Percent_Identity=46.9298245614035, Blast_Score=1008, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1140, Percent_Identity=46.9298245614035, Blast_Score=1008, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1140, Percent_Identity=46.9298245614035, Blast_Score=1008, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1156, Percent_Identity=46.4532871972318, Blast_Score=998, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1156, Percent_Identity=46.4532871972318, Blast_Score=998, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1156, Percent_Identity=46.4532871972318, Blast_Score=998, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1156, Percent_Identity=46.4532871972318, Blast_Score=998, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1156, Percent_Identity=46.4532871972318, Blast_Score=998, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=453, Percent_Identity=44.3708609271523, Blast_Score=349, Evalue=7e-96,
Organism=Drosophila melanogaster, GI24651759, Length=414, Percent_Identity=43.4782608695652, Blast_Score=311, Evalue=2e-84,
Organism=Drosophila melanogaster, GI161076407, Length=516, Percent_Identity=30.0387596899225, Blast_Score=211, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24586460, Length=516, Percent_Identity=30.0387596899225, Blast_Score=211, Evalue=2e-54,
Organism=Drosophila melanogaster, GI161076409, Length=516, Percent_Identity=30.0387596899225, Blast_Score=211, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24586458, Length=516, Percent_Identity=30.0387596899225, Blast_Score=211, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 120425; Mature: 120425

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS00165 DEHYDRATASE_SER_THR ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQIGDIGHPVHA
CCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCHHH
YLSVDEIVATARRAGADAIYPGYGFLSENPDLAAACAAAGISFVGPSAEVLELAGNKSRA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCHHHHHHCCCCHHH
IAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAVAGGGGRGMRRVGDIAALPEA
HHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIE
HHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHH
LAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVT
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEHHH
EEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRITTEDPANGFRPDTGRISA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEE
LRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLPTAVSRARRAIAEFRIRGVST
EEECCCCCEEECCCCCCCCCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
NIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRP
CCHHHHHHHCCCCCCCCCEEHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEECCCCCCCC
STIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLA
CCCCCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TRVRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICL
HHHHHCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALNNIESMRPAIDAVRETGSA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVLAIKDMAGLLRPPAAQRLVSA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHHHHHHH
LRSRFDLPVHLHTHDTPGGQLASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAH
HHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TEYDTGLSLSAVCALEPYWEALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIAL
CCCCCCCCEEHHEECCHHHHHHHHHHCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
GLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSADEFASDPARFGIP
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHCCCC
ESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIALSSVGAKRQATLNR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHH
LLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGEEHRVKLERGVELLIGLEAISEPDE
CCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHCCCCHHHHHHHCCCEEEEEHHHHCCCHH
RGMRTVMCILNGQLRPVLVRDRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERV
HHHHEEHHHHCCCCCEEEEECCHHHHHCCCHHHCCCCCCCEEECCHHHHHHHHHHHCCCC
GAGQTIATIEAMKMEAPITAPVAGTVERVAVSDTAQVEGGDLLVVVS
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHEECCCCEECCCCEEEEEC
>Mature Secondary Structure
MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQIGDIGHPVHA
CCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCHHH
YLSVDEIVATARRAGADAIYPGYGFLSENPDLAAACAAAGISFVGPSAEVLELAGNKSRA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCHHHHHHCCCCHHH
IAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAVAGGGGRGMRRVGDIAALPEA
HHHHHHCCCCEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIE
HHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHH
LAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVT
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEHHH
EEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRITTEDPANGFRPDTGRISA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEE
LRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLPTAVSRARRAIAEFRIRGVST
EEECCCCCEEECCCCCCCCCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
NIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRP
CCHHHHHHHCCCCCCCCCEEHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEECCCCCCCC
STIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLA
CCCCCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TRVRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICL
HHHHHCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALNNIESMRPAIDAVRETGSA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVLAIKDMAGLLRPPAAQRLVSA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHHHHHHH
LRSRFDLPVHLHTHDTPGGQLASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAH
HHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TEYDTGLSLSAVCALEPYWEALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIAL
CCCCCCCCEEHHEECCHHHHHHHHHHCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
GLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSADEFASDPARFGIP
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHCCCC
ESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIALSSVGAKRQATLNR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHH
LLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGEEHRVKLERGVELLIGLEAISEPDE
CCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHCCCCHHHHHHHCCCEEEEEHHHHCCCHH
RGMRTVMCILNGQLRPVLVRDRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERV
HHHHEEHHHHCCCCCEEEEECCHHHHHCCCHHHCCCCCCCEEECCHHHHHHHHHHHCCCC
GAGQTIATIEAMKMEAPITAPVAGTVERVAVSDTAQVEGGDLLVVVS
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHEECCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]