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The map label for this gene is mmpL7

Identifier: 148824131

GI number: 148824131

Start: 3296543

End: 3299305

Strand: Direct

Name: mmpL7

Synonym: TBFG_12956

Alternate gene names: 148824131

Gene position: 3296543-3299305 (Clockwise)

Preceding gene: 148824130

Following gene: 148824132

Centisome position: 74.51

GC content: 66.02

Gene sequence:

>2763_bases
ATGCCTAGTCCGGCTGGCCGTCTACACAGAATTCGGTATATCCGTTTGAAAAAGTCCTCCCCGGACTGCCGCGCCACCAT
CACCAGCGGGTCAGCCGACGGTCAGCGAAGGTCACCCCGGCTCACCAACCTGCTCGTCGTCGCCGCCTGGGTTGCCGCGG
CGGTGATCGCAAATCTGCTTCTCACGTTCACGCAAGCAGAACCGCACGACACCAGCCCGGCGCTGCTGCCACAAGATGCC
AAGACAGCCGCCGCCACCAGCCGGATTGCGCAGGCTTTCCCCGGCACCGGTAGCAACGCTATCGCCTATCTCGTCGTGGA
AGGCGGCAGCACGCTTGAGCCGCAGGACCAGCCTTACTACGACGCCGCCGTCGGTGCCCTGCGCGCCGACACCCGCCACG
TGGGATCCGTCCTCGACTGGTGGTCAGATCCCGTCACCGCCCCGCTGGGAACCAGCCCCGACGGCCGCTCCGCTACGGCC
ATGGTGTGGCTGCGGGGCGAGGCGGGCACCACCCAAGCTGCCGAATCCCTCGATGCCGTCCGATCGGTGCTGCGCCAGTT
ACCGCCCAGTGAGGGGCTTCGCGCCAGCATCGTGGTCCCGGCAATCACCAACGACATGCCGATGCAGATAACCGCCTGGC
AGAGCGCGACGATCGTGACCGTTGCGGCGGTGATCGCCGTCCTACTGCTGCTGCGGGCGCGCCTGTCGGTGCGGGCCGCG
GCGATCGTGCTGCTGACCGCGGACTTGTCGCTTGCGGTGGCCTGGCCGCTGGCCGCGGTGGTGCGGGGACACGATTGGGG
AACCGATTCGGTATTTTCTTGGACGCTGGCCGCGGTCCTGACGATCGGAACCATCACCGCAGCCACCATGCTGGCCGCGC
GGCTCGGGTCCGACGCAGGTCATTCGGCCGCGCCCACATACCGCGACAGCCTGCCCGCGTTCGCCCTGCCCGGGGCGTGT
GTCGCCATATTCACCGGCCCGCTGCTGCTGGCCCGAACCCCAGCGCTGCACGGAGTTGGCACTGCCGGGCTAGGTGTCTT
TGTGGCACTTGCGGCTTCGTTGACGGTGCTGCCTGCCCTGATCGCGCTTGCCGGAGCGTCACGGCAGTTACCGGCACCAA
CCACGGGTGCCGGCTGGACAGGCCGGTTGTCGCTACCCGTCTCTTCTGCTTCGGCCCTGGGCACAGCGGCAGTGCTGGCG
ATCTGCATGCTACCCATCATCGGGATGCGGTGGGGTGTGGCCGAGAACCCGACAAGGCAAGGCGGCGCACAAGTCCTTCC
GGGGAATGCGCTTCCCGATGTGGTGGTGATCAAATCCGCTCGGGACCTGAGGGACCCAGCCGCGCTCATCGCCATCAACC
AGGTCAGCCACCGTCTGGTGGAGGTTCCCGGTGTGCGCAAGGTGGAGTCGGCGGCATGGCCGGCCGGTGTCCCGTGGACC
GACGCCTCGCTCAGTTCCGCGGCCGGCAGGCTCGCCGACCAGCTGGGTCAGCAGGCCGGATCGTTCGTGCCGGCGGTGAC
TGCGATCAAATCGATGAAGTCCATAATCGAACAGATGAGCGGCGCGGTCGACCAACTGGACAGCACCGTGAACGTGACTC
TCGCCGGGGCAAGGCAAGCACAGCAATACCTCGATCCCATGCTCGCCGCCGCGCGGAACCTCAAAAACAAAACCACCGAA
CTGTCGGAATACCTGGAAACGATCCACACCTGGATTGTCGGCTTCACAAACTGCCCCGACGACGTCCTGTGCACGGCCAT
GCGCAAGGTCATTGAACCCTACGACATCGTGGTCACCGGCATGAACGAGCTGTCCACTGGCGCCGACCGCATCTCCGCGA
TATCGACACAGACAATGAGCGCGTTGTCCTCGGCACCGCGGATGGTGGCGCAGATGCGGTCGGCGCTAGCACAGGTGCGC
TCGTTCGTACCCAAGCTGGAAACAACCATCCAGGACGCCATGCCGCAAATAGCGCAGGCGTCGGCGATGCTGAAGAATCT
CAGCGCCGATTTCGCCGATACCGGTGAGGGCGGCTTCCACCTGTCCAGGAAGGACCTGGCGGACCCGTCGTACCGGCACG
TACGGGAATCGATGTTCTCGTCAGACGGAACCGCCACCCGGCTGTTCCTCTATTCTGACGGACAACTGGACCTTGCTGCG
GCAGCACGCGCGCAGCAGCTCGAGATCGCCGCGGGCAAGGCGATGAAATACGGAAGCCTGGTCGACAGCCAGGTCACGGT
GGGTGGGGCCGCGCAAATAGCCGCGGCTGTCCGCGATGCCCTCATCCACGATGCTGTGCTACTGGCCGTTATCTTGCTCA
CGGTAGTGGCTCTGGCCAGCATGTGGCGCGGTGCCGTCCACGGTGCTGCGGTTGGCGTGGGTGTGCTGGCCTCTTACCTC
GCCGCCCTGGGGGTCTCGATTGCACTGTGGCAACACCTACTGGATCGCGAGCTCAACGCCTTGGTCCCGCTGGTGTCGTT
CGCCGTCCTCGCTTCGTGCGGCGTCCCGTATCTCGTTGCCGGCATCAAAGCCGGTCGTATCGCCGACGAGGCAACGGGTG
CGCGGTCCAAGGGGGCGGTATCCGGGCGGGGAGCGGTTGCGCCGCTTGCGGCGCTCGGTGGCGTATTCGGCGCTGGCCTG
GTGCTGGTGTCGGGAGGTTCCTTCAGCGTGCTCAGTCAGATTGGCACGGTTGTTGTGCTCGGTCTGGGCGTGCTGATCAC
GGTGCAGCGAGCGTGGCTTCCGACCACGCCAGGGCGGCGTTGA

Upstream 100 bases:

>100_bases
GTTCTGGTTGCGCCTGGCTCGATCCCCATTACCACCAGCGGGAAGGTCAGGAGAGGGGCGTGTGTCGAGCAATATCGACA
GGATCAATTCGCCCGCTTGG

Downstream 100 bases:

>100_bases
CCGCCTGTTCGAGACCCCATGCCACGCTCGGCTGGCCGACGACGATCACCCATCGCAGACACCACACTTGGTAGGGGTTG
CCAGTTGTTGGCCGGGTGAG

Product: transmembrane transport protein mmpL7

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 920; Mature: 919

Protein sequence:

>920_residues
MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDA
KTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATA
MVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAA
AIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGAC
VAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLA
ICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWT
DASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTE
LSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVR
SFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAA
AARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYL
AALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGL
VLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR

Sequences:

>Translated_920_residues
MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDA
KTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATA
MVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAA
AIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGAC
VAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLA
ICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWT
DASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTE
LSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVR
SFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAA
AARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYL
AALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGL
VLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR
>Mature_919_residues
PSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDAK
TAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAM
VWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAA
IVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACV
AIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAI
CMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWTD
ASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTEL
SEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRS
FVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAAA
ARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYLA
ALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLV
LVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MMPL7_MYCBO (P65371)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856612.1
- ProteinModelPortal:   P65371
- EnsemblBacteria:   EBMYCT00000014963
- GeneID:   1092139
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2967
- GeneTree:   EBGT00050000015043
- HOGENOM:   HBG568927
- OMA:   QYLAGRE
- ProtClustDB:   CLSK792178
- BioCyc:   MBOV233413:MB2967-MONOMER
- InterPro:   IPR004869

Pfam domain/function: PF03176 MMPL

EC number: NA

Molecular weight: Translated: 95123; Mature: 94992

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d36a7cc)-; HASH(0x1c6861d0)-; HASH(0x1c6a45d0)-; HASH(0x1d17cf00)-; HASH(0x1d1b2d54)-; HASH(0x1d120e68)-; HASH(0x1c458ffc)-; HASH(0x1a666db4)-; HASH(0x1c4a8ddc)-; HASH(0x1cd32080)-; HASH(0x1af6c28c)-; HASH(0x1c13f6c4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLL
CCCCCCHHHEEEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYY
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
DAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
RSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAA
HHHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAG
EEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPAL
CCCCCCHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQ
HHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWT
CCCEECCCCCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
DASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
QQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEC
MNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQA
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAA
HHHHHHHCCCCCCCCCCCCEECHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEHHH
AARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALAS
HHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVL
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
GLGVLITVQRAWLPTTPGRR
HHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
PSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLL
CCCCCHHHEEEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYY
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
DAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
RSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAA
HHHHHHCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAG
EEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPAL
CCCCCCHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQ
HHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWT
CCCEECCCCCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
DASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
QQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEC
MNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQA
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAA
HHHHHHHCCCCCCCCCCCCEECHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEHHH
AARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALAS
HHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVL
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
GLGVLITVQRAWLPTTPGRR
HHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972