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The map label for this gene is 148824102

Identifier: 148824102

GI number: 148824102

Start: 3231392

End: 3233227

Strand: Reverse

Name: 148824102

Synonym: TBFG_12927

Alternate gene names: NA

Gene position: 3233227-3231392 (Counterclockwise)

Preceding gene: 148824103

Following gene: 148824101

Centisome position: 73.08

GC content: 64.81

Gene sequence:

>1836_bases
ATGTTAGCTTGGCGGCAACTCAACGATCTGGAGGAAACGGTGACCTACGACGTGATCATTCGCGACGGACTGTGGTTCGA
CGGCACCGGCAATGCGCCATTGACTCGCACTCTGGGCATTCGCGACGGCGTGGTGGCCACGGTGGCTGCCGGCGCACTGG
ACGAGACCGGCTGCCCGGAGGTGGTTGATGCGGCGGGGAAGTGGGTCGTGCCTGGCTTCATCGACGTGCACACCCACTAT
GACGCCGAGGTGTTGCTCGATCCTGGTTTGCGGGAGTCGGTGCGCCACGGTGTCACCACGGTGCTGCTGGGAAACTGCTC
GTTGTCGACGGTCTACGCCAACTCCGAGGATGCCGCCGACCTGTTCAGCCGTGTTGAAGCGGTGCCCCGCGAATTTGTCC
TGGGTGCCCTGCGGGACAACCAGACGTGGTCGACGCCCGCGGAGTACATCGAAGCGATCGACGCCCTGCCCCTCGGGCCG
AATGTGAGTTCACTGCTTGGCCATTCGGATCTGCGGACCGCGGTACTGGGCCTTGATCGTGCCACCGACGACACCGTCCG
GCCCACCGAAGCCGAGCTGGCGAAGATGGCGAAACTGCTCGATGAGGCGCTCGAGGCCGGGATGCTGGGCATGTCCGGGA
TGGACGCCGCTATCGACAAGCTCGACGGCGACCGCTTCCGCTCGCGTGCGCTGCCGTCCACCTTCGCGACCTGGCGGGAG
CGTCGCAAGCTGATCTCGGTGCTGCGCCACCGGGGCCGGATACTGCAGAGCGCACCCGACGTCGACAACCCGGTGTCCGC
GCTGCTGTTTTTCTTGGCCAGCAGCCGGATATTCAACCGGCGCAAGGGCGTTCGAATGAGCATGTTGGTGTCCGCCGACG
CCAAGTCGATGCCGCTGGCGGTACACGTGTTCGGGTTGGGCACCCGCGTGCTGAACAAGCTCTTAGGCTCTCAGGTGCGA
TTCCAGCATCTGCCGGTCCCGTTCGAGCTGTACTCCGACGGCATCGACCTGCCGGTCTTCGAGGAGTTCGGCGCCGGAAC
GGCGGCCCTTCATCTGCGTGACCAACTGCAGCGCAACGAGCTCCTGGCCGACAGGTCTTACCGCCGGTCGTTCCGGCGCG
AGTTCGATCGCATCAAGCTCGGACCTTCGTTGTGGCATCGGGACTTCCACGACGCCGTGATCGTCGAATGCCCGGATAAG
TCGTTGATCGGTAAGAGTTTCGGGGCAATAGCCGACGAGCGCGGGCTGCACCCGCTGGACGCGTTCCTCGATGTGCTGGT
GGACAACGGGGAGCGCAATGTCCGATGGACCACCATCGTCGCCAATCACCGGCCCAACCAGCTGAACAAGCTGGCCGCCG
AACCGAGTGTCCACATGGGCTTCTCCGACGCCGGCGCGCACCTGCGCAATATGGCGTTCTACAACTTCGGGCTTCGGCTG
CTCAAACGAGCCAGAGACGCCGACCGGGCCGGACAACCGTTTCTGTCCATCGAGCGGGCAGTGTATCGCCTCACCGGTGA
GTTGGCCGAGTGGTTCGGTATAGGCGCGGGCACGTTGCGCCAGGGTGACCGTGCGGACTTCGCGGTGATTGACCCTACCC
ACCTAGATGAATCGGTGGACGGGTACCACGAGGAGGCGGTGCCCTACTATGGCGGTCTGCGACGCATGGTCAACCGCAAC
GATGCGACCGTGGTTGCGACGGGCGTGGGCGGCACCGTGGTATTCCGCGGAGGCCAGTTCGGAGGTCAGTTCCGCGACGG
CTACGGGCAGAACGTGAAGTCGGGTCGCTACCTGCGGGCGGGTGAGCTCGGCGCCGCTCTGAGCCGTTCTGCCTGA

Upstream 100 bases:

>100_bases
CGACCACAACGGCGCCGGGGCCCGGTCGCTGACACCCACTTGACCAGCGCCGCGGCAGCGAAGCGGCGTCAGCCAAAAAG
ATTGCGAGTGATCGCTATCT

Downstream 100 bases:

>100_bases
CATGGCCAGGACCCAGCAGCAGCGCCGCGAAGAAACCGTTGCACGGCTTCTGCAGGCCAGCATCGACACGATCATCGAGG
TCGGCTACGCGCGGGCATCG

Product: D-amino acid aminohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPGFIDVHTHY
DAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGP
NVSSLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLAVHVFGLGTRVLNKLLGSQVR
FQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDK
SLIGKSFGAIADERGLHPLDAFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRN
DATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA

Sequences:

>Translated_611_residues
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPGFIDVHTHY
DAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGP
NVSSLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLAVHVFGLGTRVLNKLLGSQVR
FQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDK
SLIGKSFGAIADERGLHPLDAFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRN
DATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA
>Mature_611_residues
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPGFIDVHTHY
DAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGP
NVSSLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLAVHVFGLGTRVLNKLLGSQVR
FQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDK
SLIGKSFGAIADERGLHPLDAFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRN
DATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA

Specific function: Unknown

COG id: COG3653

COG function: function code Q; N-acyl-D-aspartate/D-glutamate deacylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2913_MYCTU (P65530)

Other databases:

- EMBL:   BX842581
- EMBL:   AE000516
- PIR:   D70928
- RefSeq:   NP_217429.1
- RefSeq:   NP_337493.1
- ProteinModelPortal:   P65530
- SMR:   P65530
- EnsemblBacteria:   EBMYCT00000003852
- EnsemblBacteria:   EBMYCT00000070791
- GeneID:   887809
- GeneID:   925294
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2981
- KEGG:   mtu:Rv2913c
- TIGR:   MT2981
- TubercuList:   Rv2913c
- GeneTree:   EBGT00050000016209
- HOGENOM:   HBG529050
- OMA:   VANHRPK
- ProtClustDB:   CLSK792156
- GO:   GO:0005829
- InterPro:   IPR013108
- InterPro:   IPR011059

Pfam domain/function: PF07969 Amidohydro_3; SSF51338 Metalo_hydrolase

EC number: NA

Molecular weight: Translated: 67206; Mature: 67206

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPE
CCCCHHHHHHHHHHEEEEEEECCEEECCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCH
VVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAAD
HHHCCCCEECCCEEEEECCCCCEEEECCCHHHHHHCCCEEEEEECCCEEEEECCCCHHHH
LFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDR
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCC
ATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCHHHHHHHH
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLA
HHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEE
VHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNE
EEEEHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCCCCCCHHHHCCCCEEHHHHHHHHHHH
LLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDKSLIGKSFGAIADERGLHPLD
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHCHHHCCCCCHHH
AFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
HHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVD
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCHHCCCHHC
GYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRA
CHHHHCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEC
GELGAALSRSA
CCHHHHHHCCC
>Mature Secondary Structure
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPE
CCCCHHHHHHHHHHEEEEEEECCEEECCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCH
VVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAAD
HHHCCCCEECCCEEEEECCCCCEEEECCCHHHHHHCCCEEEEEECCCEEEEECCCCHHHH
LFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDR
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCC
ATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHCCCHHHHHHHH
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLA
HHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEE
VHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNE
EEEEHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCCCCCCHHHHCCCCEEHHHHHHHHHHH
LLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDKSLIGKSFGAIADERGLHPLD
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHCHHHCCCCCHHH
AFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
HHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVD
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCHHCCCHHC
GYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRA
CHHHHCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEC
GELGAALSRSA
CCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036