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The map label for this gene is cdsA

Identifier: 148824070

GI number: 148824070

Start: 3202230

End: 3203150

Strand: Reverse

Name: cdsA

Synonym: TBFG_12895

Alternate gene names: 148824070

Gene position: 3203150-3202230 (Counterclockwise)

Preceding gene: 148824071

Following gene: 148824069

Centisome position: 72.4

GC content: 64.28

Gene sequence:

>921_bases
GTGACAACCAACGATGCCGGCACCGGAAACCCCGCCGAGCAGCCGGCGCGTGGTGCTAAACAGCAGCCGGCGACCGAAAC
GTCCCGCGCCGGCCGTGATTTGCGCGCAGCGATCGTGGTGGGCCTTTCCATAGGCCTAGTCCTCATCGCGGTGCTGGTGT
TCGTTCCGCGCGTTTGGGTTGCCATCGTGGCCGTCGCCACCTTGGTCGCTACCCATGAGGTGGTGCGGAGGTTGCGGGAA
GCGGGCTATCTCATCCCGGTTATCCCGTTGCTGATTGGCGGGCAGGCCGCGGTGTGGCTGACCTGGCCGTTCGGCGCGGT
CGGCGCATTGGCGGGCTTTGGTGGCATGGTCGTTGTCTGCATGATTTGGCGACTGTTCATGCAGGACAGCGTGACGCGCC
CGACGACCGGCGGTGCACCGTCGCCGGGAAACTACTTGTCCGACGTCTCGGCCACGGTCTTCCTGGCCGTGTGGGTCCCA
TTGTTCTGCTCTTTCGGCGCAATGCTGGTCTACCCGGAAAATGGCTCGGGATGGGTGTTCTGCATGATGATCGCGGTCAT
CGCTTCCGATGTCGGCGGCTACGCCGTGGGGGTGTTGTTTGGCAAGCATCCGATGGTTCCGACGATCAGCCCGAAGAAGT
CGTGGGAGGGCTTTGCCGGTTCGCTGGTGTGCGGGATCACCGCAACGATCATCACCGCGACTTTCCTGGTCGGCAAAACG
CCGTGGATTGGTGCACTGCTCGGCGTGCTTTTCGTGCTCACCACCGCGCTGGGCGACCTGGTGGAGTCGCAGGTCAAACG
TGACCTCGGCATCAAAGACATGGGCCGCCTGCTACCCGGCCACGGCGGTCTGATGGACCGGCTCGACGGCATACTGCCTT
CCGCGGTGGCGGCCTGGATAGTCCTCACACTGCTGCCCTGA

Upstream 100 bases:

>100_bases
GACAAGACCACGCACCAATACGTCACCCAAATTGATGAGCTGGTTAAACACAAAGAAGGCGAGCTGCTGGAGGTCTAGCG
GCCGCTCAGCAACAAAATCC

Downstream 100 bases:

>100_bases
CAACGGCGATACTGGACAGGTCATGGTCCCCGAGTTGATGTTCGATGAGCCGCGTCCGGGTCGGCCGCCGCGGCACCTGG
CCGATCTCGACGCGGCGGGC

Product: integral membrane phosphatidate cytidylyltransferase cdsA

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLRE
AGYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVP
LFCSFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKT
PWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWIVLTLLP

Sequences:

>Translated_306_residues
MTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLRE
AGYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVP
LFCSFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKT
PWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWIVLTLLP
>Mature_305_residues
TTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREA
GYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVPL
FCSFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKTP
WIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWIVLTLLP

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=156, Percent_Identity=40.3846153846154, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787677, Length=108, Percent_Identity=37.962962962963, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_MYCBO (P63759)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856550.1
- EnsemblBacteria:   EBMYCT00000015167
- GeneID:   1092203
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2905c
- GeneTree:   EBGT00050000017496
- HOGENOM:   HBG732679
- OMA:   CALLWIT
- ProtClustDB:   CLSK792142
- BioCyc:   MBOV233413:MB2905C-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 32035; Mature: 31904

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b1aa5bc)-; HASH(0x1c950824)-; HASH(0x13abae74)-; HASH(0x1cdc3260)-; HASH(0x1c83d334)-; HASH(0x1cdd32a4)-; HASH(0x1cdac4dc)-; HASH(0x1cdb4588)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWV
CCCCCCCCCCCCHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
MIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVPLFCSFGAMLVYPENGSGWVF
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
CMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKT
HHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VLTLLP
HHHHCH
>Mature Secondary Structure 
TTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWV
CCCCCCCCCCCHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972