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The map label for this gene is mpt53

Identifier: 148824068

GI number: 148824068

Start: 3200406

End: 3200927

Strand: Reverse

Name: mpt53

Synonym: TBFG_12893

Alternate gene names: 148824068

Gene position: 3200927-3200406 (Counterclockwise)

Preceding gene: 148824069

Following gene: 148824067

Centisome position: 72.35

GC content: 62.64

Gene sequence:

>522_bases
ATGAGTCTTCGCCTGGTGTCCCCGATCAAGGCGTTTGCGGACGGCATTGTGGCCGTTGCTATCGCGGTTGTCCTGATGTT
CGGTCTGGCCAATACACCGCGAGCGGTGGCAGCCGATGAACGTCTGCAGTTCACCGCAACCACGCTCAGCGGTGCTCCCT
TCGATGGCGCAAGCCTGCAAGGCAAGCCGGCGGTGTTGTGGTTCTGGACGCCGTGGTGCCCGTTCTGCAACGCAGAAGCC
CCCAGCCTCAGCCAGGTAGCGGCCGCTAATCCGGCGGTCACCTTCGTCGGAATCGCCACCCGCGCCGACGTCGGGGCGAT
GCAGAGCTTTGTCTCGAAGTACAACCTGAATTTCACCAACCTCAATGACGCCGATGGTGTGATCTGGGCCCGCTACAACG
TGCCTTGGCAACCGGCATTTGTGTTCTATCGCGCGGACGGCACATCGACGTTCGTCAACAACCCCACCGCGGCCATGTCT
CAGGACGAGCTGTCCGGCCGGGTGGCTGCGCTGACGTCCTGA

Upstream 100 bases:

>100_bases
GCGGACAGCTGGCCGCGAGCGCAGGGGGCGCCGGGATGTACTGAACCGTCACGGAGCGTATTACGTCATTAGGTCAAAAC
ACGAACAAGTGAGGTCTGTC

Downstream 100 bases:

>100_bases
CCCGGTGAACGAGGCGCTGATCGGTTTGGCGTTCGCCGCCGGGTTGGTGGCTGCGCTGAACCCATGCGGGTTTGCCATGT
TGCCGGCCTACCTGCTGTTG

Product: soluble secreted antigen mpt53 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEA
PSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMS
QDELSGRVAALTS

Sequences:

>Translated_173_residues
MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEA
PSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMS
QDELSGRVAALTS
>Mature_172_residues
SLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEAP
SLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQ
DELSGRVAALTS

Specific function: Disulfide oxidoreductase that catalyzes the oxidation of reduced, unfolded secreted proteins to form disulfide bonds. Despite a weak homology to thioredoxin this cannot serve as a substrate for thioredoxin reductase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MPT53_MYCBO (P0A619)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856548.1
- ProteinModelPortal:   P0A619
- SMR:   P0A619
- EnsemblBacteria:   EBMYCT00000017241
- GeneID:   1092205
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2903c
- GeneTree:   EBGT00050000015916
- HOGENOM:   HBG565170
- OMA:   FVNNPTS
- ProtClustDB:   CLSK792139
- BioCyc:   MBOV233413:MB2903C-MONOMER
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF08534 Redoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 18383; Mature: 18252

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQ
CCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCC
GKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTN
CCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCC
LNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDELSGRVAALTS
CCCCCCEEEEEECCCCCCEEEEEECCCCEEECCCCCCCCCCHHHCCEEEEECC
>Mature Secondary Structure 
SLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQ
CCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCC
GKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTN
CCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCC
LNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDELSGRVAALTS
CCCCCCEEEEEECCCCCCEEEEEECCCCEEECCCCCCCCCCHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972