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The map label for this gene is trkA

Identifier: 148823882

GI number: 148823882

Start: 3021979

End: 3022641

Strand: Direct

Name: trkA

Synonym: TBFG_12707

Alternate gene names: 148823882

Gene position: 3021979-3022641 (Clockwise)

Preceding gene: 148823881

Following gene: 148823885

Centisome position: 68.3

GC content: 66.37

Gene sequence:

>663_bases
ATGAAAGTAGCTGTCGCCGGAGCGGGTGCGGTGGGCCGCTCGGTCACCCGCGAACTCGTGGAAAACGGACACGACATCAC
CCTGATCGAGCGCAACCCCGACCACCTCGACGCCGCCGCCATCCCGGAGGCGCATTGGCGGCTTGGCGATGCCTGCGAAC
TGAGCCTGCTGGAGTCGATTCACCTCGAAGAGTTCGACGTGGTCGTCGCCGCCACCGGGGACGACAAGGTCAACGTGGTG
CTCAGCCTGCTAGCCAAGACCGAATTCGCGGTGCCGCGGGTGGTGGCCCGGGTCAACGATCCCCGCAACGAGTGGCTGTT
CAACGACGCCTGGGGGGTCGACGTCGCGGTGTCCACACCCCGCATGCTGGCGTCGCTGATCGAAGAGGCCGTCACGATCG
GCGACTTGGTGCGGCTGATGGAGTTCCGCACGGGTCAGGCCAATCTGGTAGAGATCACCCTGCCCGACAACACGCCGTGG
GGCGGCAAACCGGTGCGCAAACTTCAGCTGCCGCGGGATGCCGCGCTGGTGACAATCCTGCGCGGGCCACGAGTCATCGT
GCCGGAGGCCGACGAGCCGCTGGAAGGCGGCGACGAGTTGCTCTTCGTCGCAGTCACCGAAGCCGAGGAGGAGCTGAGCA
GGCTGCTGCTGCCGTCCATGTAA

Upstream 100 bases:

>100_bases
GCGATAAGGTCTATATCGCTGCGATATCCGGCCGGGCCGCAGAGGCAGCGGCCATCGCAGCCTTGCCACCCAGTGAGGAC
TTCGAGTCGGGGGCTCGACG

Downstream 100 bases:

>100_bases
CCGGCGGGCTCTACTCGCGGCCGGCGTCGGCGTCGAATTCAGCTGCACCTCCGACGGCCGCGGCGTCGTGAGAGGCCAAG
ATGGCGCGCTGGGCTGCCTT

Product: trk system potassium uptake protein ceoC

Products: NA

Alternate protein names: K(+)-uptake protein trkA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESIHLEEFDVVVAATGDDKVNVV
LSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPW
GGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM

Sequences:

>Translated_220_residues
MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESIHLEEFDVVVAATGDDKVNVV
LSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPW
GGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM
>Mature_220_residues
MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESIHLEEFDVVVAATGDDKVNVV
LSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPW
GGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM

Specific function: Part of a potassium transport system

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain

Homologues:

Organism=Escherichia coli, GI1789685, Length=232, Percent_Identity=24.5689655172414, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRKA_MYCTU (O07194)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- EMBL:   AF026541
- PIR:   G70529
- RefSeq:   NP_337267.1
- RefSeq:   YP_177901.1
- ProteinModelPortal:   O07194
- EnsemblBacteria:   EBMYCT00000002800
- EnsemblBacteria:   EBMYCT00000072530
- GeneID:   887493
- GeneID:   925519
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2766
- KEGG:   mtu:Rv2692
- TIGR:   MT2766
- TubercuList:   Rv2692
- GeneTree:   EBGT00050000017264
- HOGENOM:   HBG312741
- OMA:   LGRPKDY
- ProtClustDB:   CLSK881402
- GO:   GO:0005488
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148
- Gene3D:   G3DSA:3.40.50.720
- PRINTS:   PR00335

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N

EC number: NA

Molecular weight: Translated: 23948; Mature: 23948

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS51202 RCK_C; PS51201 RCK_N

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESI
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCHHHHCCCCHHHHHHHHHC
HLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTP
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEECCCCCCEEEECCH
RMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPWGGKPVRKLQLPRDAALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHEECCCCCCEEEEEE
RGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM
CCCEEEECCCCCCCCCCCEEEEEEEECCHHHHHHHHCCCC
>Mature Secondary Structure
MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESI
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCHHHHCCCCHHHHHHHHHC
HLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTP
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEECCCCCCEEEECCH
RMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPWGGKPVRKLQLPRDAALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHEECCCCCCEEEEEE
RGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM
CCCEEEECCCCCCCCCCCEEEEEEEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 9784509