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The map label for this gene is pgsA1

Identifier: 148823806

GI number: 148823806

Start: 2953276

End: 2953929

Strand: Reverse

Name: pgsA1

Synonym: TBFG_12631

Alternate gene names: 148823806

Gene position: 2953929-2953276 (Counterclockwise)

Preceding gene: 148823807

Following gene: 148823805

Centisome position: 66.76

GC content: 67.58

Gene sequence:

>654_bases
ATGAGCAAGCTGCCCTTCCTGTCCCGGGCGGCGTTCGCCCGGATTACCACCCCGATCGCCAGGGGACTGCTGCGGGTCGG
CCTCACGCCGGACGTCGTCACCATCCTGGGCACCACCGCGTCGGTGGCGGGAGCGCTGACGCTGTTCCCGATGGGCAAGC
TGTTCGCGGGTGCGTGTGTGGTGTGGTTCTTCGTGTTGTTCGACATGCTGGACGGGGCGATGGCCCGGGAGCGCGGGGGC
GGCACTCGCTTCGGCGCGGTGCTGGACGCCACCTGTGACCGCATCAGTGACGGCGCGGTGTTCTGCGGTCTGCTGTGGTG
GATAGCGTTTCACATGCGCGACCGACCGCTGGTGATCGCGACCTTGATCTGTCTGGTCACCTCGCAGGTGATCTCTTACA
TCAAGGCCCGGGCGGAGGCCAGCGGGCTGCGCGGCGACGGCGGCTTCATCGAACGGCCGGAACGGTTGATCATCGTGCTG
ACCGGCGCCGGGGTGTCGGACTTCCCGTTTGTGCCCTGGCCGCCGGCGTTGTCGGTGGGGATGTGGCTGCTGGCCGTCGC
CAGCGTGATCACCTGCGTGCAGCGGTTGCACACGGTCTGGACTTCACCCGGAGCCATCGATCGGATGGCGATTCCTGGAA
AGGGCGACCGGTGA

Upstream 100 bases:

>100_bases
GCGATGCGAATTTCATCACCATCATCGGGGGCTCCAAGGTGATTCCGCAGCTGCTGCGCGACACCCGTCGGCTGCTTGCC
ACCGAGTGGGCTCGGCAACC

Downstream 100 bases:

>100_bases
TTGCCGGCCTTAAGGGCTTGAAGCTGCCCAAAGATCCGCGCAGTTCCGTGACGCGCACCGCGACCGACTGGGCGTATGCG
GCCGGCTGGATGGCCGTACG

Product: phosphatidylinositol synthase pgsA1

Products: NA

Alternate protein names: Phosphatidylinositol synthase; PI synthase

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGG
GTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVL
TGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR

Sequences:

>Translated_217_residues
MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGG
GTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVL
TGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
>Mature_216_residues
SKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGG
TRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLT
GAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR

Specific function: Unknown

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PISA_MYCTU (Q7D6W6)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842580
- PIR:   C70571
- RefSeq:   NP_337189.1
- RefSeq:   YP_177894.1
- EnsemblBacteria:   EBMYCT00000002767
- EnsemblBacteria:   EBMYCT00000069829
- GeneID:   888209
- GeneID:   925620
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2687
- KEGG:   mtu:Rv2612c
- TIGR:   MT2687
- TubercuList:   Rv2612c
- GeneTree:   EBGT00050000015462
- HOGENOM:   HBG645896
- OMA:   VIQRLAN
- ProtClustDB:   CLSK799355
- GO:   GO:0040007
- InterPro:   IPR000462

Pfam domain/function: PF01066 CDP-OH_P_transf

EC number: =2.7.8.11

Molecular weight: Translated: 23252; Mature: 23121

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c8bf9a8)-; HASH(0x1c4f6d80)-; HASH(0x1c854ce8)-; HASH(0x1c70885c)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHH
TLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
MWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCH
>Mature Secondary Structure 
SKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHH
TLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
MWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206