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The map label for this gene is ggt [H]

Identifier: 148823597

GI number: 148823597

Start: 2702663

End: 2704594

Strand: Direct

Name: ggt [H]

Synonym: TBFG_12422

Alternate gene names: 148823597

Gene position: 2702663-2704594 (Clockwise)

Preceding gene: 148823596

Following gene: 148823598

Centisome position: 61.08

GC content: 67.13

Gene sequence:

>1932_bases
GTGAGTGTTTGGTTGCGAGCGGGCGCCTTGGTGGCTGCAGTGATGCTGTCGCTGAGCGGATGTGGCGGCTTCCACGCGGG
TGCGCCAAGCACGGCCGGTCCGTGCGAGATCGTCCCCAATGGCACGCCGGCGCCCAAGACACCCCCGGCTACCGTGCCTT
CGTCGCGCAACCTCGCGACCAACCCCGAGATCGCCACCGGCTACCGCCGGGACATGACCGTGGTGCGGACCGCCCACTAT
GCGGCAGCCACCGCCAATCCGCTGGCCACTCAGGTGGCCTGCCGAGTATTGCGCGACGGTGGTACCGCCGCCGATGCCGT
CGTGGCCGCCCAGGCGGTGCTGGGGTTGGTCGAACCGCAATCCTCCGGGATCGGCGGCGGCGGATATCTGGTGTACTTCG
ACGCCCGCACGGGCTCAGTGCAGGCCTACGACGGCCGTGAGGTGGCCCCAGCGGCCGCCACCGAGAACTACCTTCGCTGG
GTCAGCGACGTCGACCGCAGCGCGCCCAGGCCCAACGCCCGAGCCTCGGGACGGTCGATCGGAGTACCGGGCATCCTGCG
AATGCTGGAGATGGTGCACAACGAGCACGGGCGCACACCCTGGCGCGACCTCTTCGGCCCCGCGGTAACGCTGGCCGATG
GCGGTTTTGACATCAGCGCCAGGATGGGCGCGGCCATCTCCGACGCTGCGCCGCAACTGCGAGACGACCCGGAGGCTCGC
AAGTATTTCCTCAATCCCGACGGCAGCCCGAAACCCGCGGGAACCCGGCTGACGAACCCCGCGTACTCAAAAACCCTGTC
CGCCATCGCCTCCGCCGGCGCCAACGCCTTCTATTCCGGCGACATTGCCCACGACATCGTGGCGGCGGCGAGCGACACAT
CGAATGGCCGCACGCCGGGCCTGTTGACCATTGAGGACCTGGCGGGTTACCTCGCCAAGAGACGCCAACCGTTGTGCACG
ACCTATCGCGGCCGGGAGATCTGCGGCATGCCATCGTCGGGTGGCGTCGCCGTGGCCGCAACCTTGGGCATCCTCGAGCA
CTTCCCGATGAGCGACTACGCGCCCAGCAAGGTCGACCTCAACGGCGGTCGCCCGACCGTGATGGGGGTTCACCTGATAG
CGGAGGCCGAACGGCTGGCCTATGCCGACCGCGACCAATATATCGCTGACGTCGATTTTGTCCGGCTGCCCGGCGGCTCG
CTCACCACGCTGGTTGACCCGGGCTACTTGGCAGCACGCGCCGCGCTAATCTCGCCGCAACACAGCATGGGCAGCGCCAG
ACCGGGGGACTTCGGCGCACCGACGGCCGTCGCCCCGCCAGTGCCTGAGCATGGCACCAGCCACCTCAGCGTCGTCGATT
CGTACGGCAATGCGGCCACGTTGACGACGACGGTGGAATCTTCGTTCGGCTCCTACCACCTGGTGGACGGATTCATCCTC
AACAACCAGCTGAGCGATTTCAGCGCCGAGCCACACGCTACTGACGGATCACCGGTGGCTAACCGGGTCGAGCCTGGGAA
GCGACCGCGCAGTTCGATGGCACCGACGTTGGTGTTCGATCACTCGTCGGCGGGGCGCGGTGCGCTGTACGCGGTGCTCG
GTTCTCCGGGCGGCTCCATGATCATCCAGTTCGTCGTGAAAACACTTGTGGCGATGCTGGATTGGGGTCTGAATCCGCAG
CAGGCGGTTTCCCTGGTCGATTTCGGCGCCGCGAACTCGCCGCACACTAACCTCGGCGGTGAGAATCCCGAGATCAACAC
TTCCGACGATGGTGATCATGACCCGCTGGTGCAAGGCCTGCGCGCGCTGGGGCATCGAGTTAATCTTGCCGAGCAATCCA
GTGGGCTCTCGGCGATCACCCGCAGCGAGGCGGGTTGGGCCGGCGGCGCCGACCCACGCCGCGAAGGCGCGGTCATGGGC
GACGATGCCTGA

Upstream 100 bases:

>100_bases
GATGGTGGCCGCGACCATGTGGGATCGCTACCGACAAGCCGTGGCCGGTCGGATCGCGGCCTAGGTCTTCTCGAAGGTCT
GCTGGAACGGATGTCCTCTG

Downstream 100 bases:

>100_bases
GCCGTTCGCCGGCGGGCGGCCAAACGAACGCGGACCACTTCGAGCCGATAATTTTGCCGGCCCTCTCGGGCTTTGTCTGC
GGTTTTACCGGCTCGGTGCA

Product: gamma-glutamyltranspeptidase precursor ggtB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MSVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAPKTPPATVPSSRNLATNPEIATGYRRDMTVVRTAHY
AAATANPLATQVACRVLRDGGTAADAVVAAQAVLGLVEPQSSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRW
VSDVDRSAPRPNARASGRSIGVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARMGAAISDAAPQLRDDPEAR
KYFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGDIAHDIVAAASDTSNGRTPGLLTIEDLAGYLAKRRQPLCT
TYRGREICGMPSSGGVAVAATLGILEHFPMSDYAPSKVDLNGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVRLPGGS
LTTLVDPGYLAARAALISPQHSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNAATLTTTVESSFGSYHLVDGFIL
NNQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTLVFDHSSAGRGALYAVLGSPGGSMIIQFVVKTLVAMLDWGLNPQ
QAVSLVDFGAANSPHTNLGGENPEINTSDDGDHDPLVQGLRALGHRVNLAEQSSGLSAITRSEAGWAGGADPRREGAVMG
DDA

Sequences:

>Translated_643_residues
MSVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAPKTPPATVPSSRNLATNPEIATGYRRDMTVVRTAHY
AAATANPLATQVACRVLRDGGTAADAVVAAQAVLGLVEPQSSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRW
VSDVDRSAPRPNARASGRSIGVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARMGAAISDAAPQLRDDPEAR
KYFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGDIAHDIVAAASDTSNGRTPGLLTIEDLAGYLAKRRQPLCT
TYRGREICGMPSSGGVAVAATLGILEHFPMSDYAPSKVDLNGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVRLPGGS
LTTLVDPGYLAARAALISPQHSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNAATLTTTVESSFGSYHLVDGFIL
NNQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTLVFDHSSAGRGALYAVLGSPGGSMIIQFVVKTLVAMLDWGLNPQ
QAVSLVDFGAANSPHTNLGGENPEINTSDDGDHDPLVQGLRALGHRVNLAEQSSGLSAITRSEAGWAGGADPRREGAVMG
DDA
>Mature_642_residues
SVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAPKTPPATVPSSRNLATNPEIATGYRRDMTVVRTAHYA
AATANPLATQVACRVLRDGGTAADAVVAAQAVLGLVEPQSSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRWV
SDVDRSAPRPNARASGRSIGVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARMGAAISDAAPQLRDDPEARK
YFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGDIAHDIVAAASDTSNGRTPGLLTIEDLAGYLAKRRQPLCTT
YRGREICGMPSSGGVAVAATLGILEHFPMSDYAPSKVDLNGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVRLPGGSL
TTLVDPGYLAARAALISPQHSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNAATLTTTVESSFGSYHLVDGFILN
NQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTLVFDHSSAGRGALYAVLGSPGGSMIIQFVVKTLVAMLDWGLNPQQ
AVSLVDFGAANSPHTNLGGENPEINTSDDGDHDPLVQGLRALGHRVNLAEQSSGLSAITRSEAGWAGGADPRREGAVMGD
DA

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=553, Percent_Identity=30.5605786618445, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI73915090, Length=553, Percent_Identity=30.5605786618445, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI73915096, Length=553, Percent_Identity=30.5605786618445, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI73915094, Length=553, Percent_Identity=30.5605786618445, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI113429324, Length=553, Percent_Identity=30.379746835443, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI113429326, Length=562, Percent_Identity=29.8932384341637, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI109148539, Length=557, Percent_Identity=26.3913824057451, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI153266885, Length=495, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI153266901, Length=491, Percent_Identity=26.6802443991853, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI30581157, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI30581155, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789856, Length=568, Percent_Identity=33.2746478873239, Blast_Score=253, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI212646519, Length=509, Percent_Identity=31.041257367387, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI72000294, Length=509, Percent_Identity=30.6483300589391, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI193208247, Length=586, Percent_Identity=30.5460750853242, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI193208245, Length=586, Percent_Identity=30.3754266211604, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17542894, Length=571, Percent_Identity=30.2977232924694, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17506189, Length=501, Percent_Identity=28.5429141716567, Blast_Score=164, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6323330, Length=480, Percent_Identity=28.9583333333333, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161077880, Length=592, Percent_Identity=28.2094594594595, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI45551474, Length=592, Percent_Identity=28.2094594594595, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI161077878, Length=592, Percent_Identity=28.2094594594595, Blast_Score=175, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24642670, Length=592, Percent_Identity=28.2094594594595, Blast_Score=175, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24642666, Length=592, Percent_Identity=28.2094594594595, Blast_Score=175, Evalue=9e-44,
Organism=Drosophila melanogaster, GI18859893, Length=484, Percent_Identity=30.1652892561983, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI161077496, Length=546, Percent_Identity=26.9230769230769, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18859741, Length=577, Percent_Identity=27.9029462738302, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 66560; Mature: 66429

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAPKTPPATVPSSRNLAT
CCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
NPEIATGYRRDMTVVRTAHYAAATANPLATQVACRVLRDGGTAADAVVAAQAVLGLVEPQ
CCCHHCCCHHCEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRWVSDVDRSAPRPNARASGRSI
CCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARMGAAISDAAPQLRDDPEAR
CCHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEHHHCCCHHHHCCCHHCCCCCHH
KYFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGDIAHDIVAAASDTSNGRTPG
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCCCCCCC
LLTIEDLAGYLAKRRQPLCTTYRGREICGMPSSGGVAVAATLGILEHFPMSDYAPSKVDL
EEEHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEC
NGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVRLPGGSLTTLVDPGYLAARAALISPQ
CCCCCEEEEEHHHHHHHHHHHCCCCCEEECCEEEECCCCCEEEEECCCHHHHHHHHCCCH
HSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNAATLTTTVESSFGSYHLVDGFIL
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHCCCCCEEEEEEEEE
NNQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTLVFDHSSAGRGALYAVLGSPGGSM
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHCCCEEEEECCCCCCCEEEEEEECCCHHH
IIQFVVKTLVAMLDWGLNPQQAVSLVDFGAANSPHTNLGGENPEINTSDDGDHDPLVQGL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
RALGHRVNLAEQSSGLSAITRSEAGWAGGADPRREGAVMGDDA
HHHHHHCCHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAPKTPPATVPSSRNLAT
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
NPEIATGYRRDMTVVRTAHYAAATANPLATQVACRVLRDGGTAADAVVAAQAVLGLVEPQ
CCCHHCCCHHCEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRWVSDVDRSAPRPNARASGRSI
CCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARMGAAISDAAPQLRDDPEAR
CCHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEHHHCCCHHHHCCCHHCCCCCHH
KYFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGDIAHDIVAAASDTSNGRTPG
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCCCCCCC
LLTIEDLAGYLAKRRQPLCTTYRGREICGMPSSGGVAVAATLGILEHFPMSDYAPSKVDL
EEEHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEC
NGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVRLPGGSLTTLVDPGYLAARAALISPQ
CCCCCEEEEEHHHHHHHHHHHCCCCCEEECCEEEECCCCCEEEEECCCHHHHHHHHCCCH
HSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNAATLTTTVESSFGSYHLVDGFIL
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHCCCCCEEEEEEEEE
NNQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTLVFDHSSAGRGALYAVLGSPGGSM
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHCCCEEEEECCCCCCCEEEEEEECCCHHH
IIQFVVKTLVAMLDWGLNPQQAVSLVDFGAANSPHTNLGGENPEINTSDDGDHDPLVQGL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
RALGHRVNLAEQSSGLSAITRSEAGWAGGADPRREGAVMGDDA
HHHHHHCCHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]