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The map label for this gene is rocD [H]

Identifier: 148823522

GI number: 148823522

Start: 2605487

End: 2606176

Strand: Reverse

Name: rocD [H]

Synonym: TBFG_12345

Alternate gene names: 148823522

Gene position: 2606176-2605487 (Counterclockwise)

Preceding gene: 148823523

Following gene: 148823521

Centisome position: 58.9

GC content: 64.78

Gene sequence:

>690_bases
GTGCTGCACGCTGGAGATACACCCATGACAAATCTCGCGGATGCCACTCAGGCCACTATGGCACTGGTCGAAAGGCATGC
AGCGCACAATTATTCGCCGCTGCCTGTGGTGGCGGCCAGCGCTGAGGGTGCGTGGATCGCCGATATCGACGGCCTGCGCT
ACCTGGACTGGCTGGCTGCGTACTCGGCGGTCAACCTTGGCCATCGCAACCCCGCGAGCACCGCCACGGCTCATGCCCAA
GTCGACACCGTCACCCTGCTGAATCGGGCCTTGCATGCCGACCGACTCGGGCCGTTGGGCGCCGCGCTTGCCCAGCTGTG
CGGCAAAGACGTGGTGTTGCCAATGAACTCTGATGCTGAAGCGGTGGAGAGCGGTCTTAGGGTCGCCCGCAAGTGGGGAG
CCGACGTCAACGGCCTCCCCGCGGGCCGGCACGATATCATTTTGGCAAACAACAACTTTCATGGCCACACCAGCAGTGTC
GTCAGCTTCTCGTCGGACCCGGCTGCGGGCAGCGGCGTCGAACCTTCTACCCCGGGACTCCGCTCGGTACCGTTTGGCGA
TGCTGCGGCACCGGCGCAGACAATCGACGACAACACCGTCGCTGACCTGCTCGAGCCGATTCCCGGCCAGGCGGGCATCA
TCGTCCCGGCCGACGACTACCTGCCGGCTGCGTCGAGCACAACGTGCTGA

Upstream 100 bases:

>100_bases
CGGTCGCGGCCATGGGTTTTGCGGCGCAGTTACGCGCAGCCGGCTTCGAGCCGGTCGGTGTCGATCTGTCCGAGCTGCTC
AAGGGCGGCGGTTCCGTCAA

Downstream 100 bases:

>100_bases
TGATCGCCGACGAAATCCAATCGGGGCTGGCCTGTACGGGTTACCCGTTCGCCTGCGACCACGGGGGTGTGCTGCCAGAC
ATTTACCTGCTCGGCAAGAC

Product: ornithine aminotransferase (N-terminus part) rocD1

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLHAGDTPMTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQ
VDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSV
VSFSSDPAAGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC

Sequences:

>Translated_229_residues
MLHAGDTPMTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQ
VDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSV
VSFSSDPAAGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
>Mature_229_residues
MLHAGDTPMTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQ
VDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSV
VSFSSDPAAGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=198, Percent_Identity=39.3939393939394, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI284507298, Length=108, Percent_Identity=39.8148148148148, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI145693181, Length=194, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1789759, Length=191, Percent_Identity=29.3193717277487, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788044, Length=191, Percent_Identity=28.2722513089005, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1786349, Length=208, Percent_Identity=25.4807692307692, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25144271, Length=211, Percent_Identity=37.4407582938389, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71981843, Length=172, Percent_Identity=37.2093023255814, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323470, Length=229, Percent_Identity=37.117903930131, Blast_Score=148, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21357415, Length=198, Percent_Identity=42.4242424242424, Blast_Score=174, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 23537; Mature: 23537

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHAGDTPMTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHH
YSAVNLGHRNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAE
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHH
AVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
RSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLHAGDTPMTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHH
YSAVNLGHRNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAE
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHH
AVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
RSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA