Click here to switch to the map view.

The map label for this gene is 148823416

Identifier: 148823416

GI number: 148823416

Start: 2485546

End: 2487084

Strand: Direct

Name: 148823416

Synonym: TBFG_12237

Alternate gene names: NA

Gene position: 2485546-2487084 (Clockwise)

Preceding gene: 148823415

Following gene: 148823419

Centisome position: 56.18

GC content: 66.86

Gene sequence:

>1539_bases
ATGCCCGCATCACGACTGGTCAGACAAGTGTCTGCGCCACGGAACCTGTTCGGGCGGCTGGTTGCCCAGGGGGGCTTCTA
CACGGCCGGGCTGCAGTTGGGCAGCGGTGCGGTGGTACTGCCGGTCATCTGCGCACATCAGGGCCTCACCTGGGCGGCTG
GGCTGTTGTATCCGGCGTTCTGCATTGGCGCCATTCTGGGAAATTCGCTGTCGCCGCTGATTCTGCAGCGCGCCGGCCAG
CTCCGGCACCTGCTGATGGCGGCGATATCGGCGACGGCGGCGGCGCTGGTTGTGTGCAACGCTGCGGTCCCCTGGACTGG
CGTTGGCGTCGCCGCGGTTTTTTTGGCGACCACGGGGGCCGGTGGTGTCGTCACCGGAGTCTCCAGCGTCGCCTACACCG
ACATGATCTCCAGCATGTTGCCCGCGGTACGGCGGGGCGAGCTACTGCTCACCCAAGGTGCCGCGGGGTCGGTGCTGGCC
ACCGGCGTCACATTGGTGATTGTGCCGATGCTGGCCCATGGCAACGAGATGGCGCGCTATCACGATCTGCTGTGGCTGGG
CGCCGCAGGTCTGGTTTGCTCCGGCATCGCGGCGCTGTTCGTCGGCCCGATGCGGTCTGTGTCCGTCACAACCGCCACCC
GAATGCCACTGCGGGAAATCTATTGGATGGGCTTCGCGATCGCCCGCTCCCAGCCGTGGTTTCGCCGGTATATGACGACT
TACCTGCTGTTCGTTCCGATCAGCCTGGGCACCACGTTCTTCAGCCTGCGCGCCGCCCAGTCCAACGGCAGTCTGCACGT
GCTGGTGATCCTTTCCAGCATTGGATTGGTCGTCGGTTCGATGCTGTGGCGACAGATAAACCGCCTGTTCGGGGTGCGTG
GCCTGCTGCTGGGCAGCGCACTGCTCAACGCCGCTGCTGCGCTGCTGTGCATGGTGGCCGAGTCGTGTGGGCAGTGGGTT
CACGCCTGGGCGTACGGCACGGCGTTCCTGCTGGCTACGGTGGCCGCTCAAACGGTGGTCGCCGCATCGATATCGTGGAT
CAGCGTCCTCGCGCCCGAGCGGTACCGCGCCACCCTGATCTGCGTTGGGTCGACCTTGGCCGCCGTCGAAGCCACCGTGC
TGGGAGTTGCGCTCGGCGGAATTGCCCAAAAGCATGCCACCATCTGGCCGGTTGTCGTCGTGCTGACACTGGCCGTAATC
GCCGCGGTGGCGAGTCTGCGCGCACCGACACGAATCGGGGTGACGGCGGACACGAGCCCGCAAGCAGCGACCTTGCAAGC
CTACCGCCCGGCCACTCCTAACCCCATCCATAGCGATGAACGTTCGACGCCGCCCGACCATCTCTCAGTCCGCCGCGGGC
AGTTACGACACGTATGGGACAGTCGCCGGCCCGCGCCACCCCTGAACCGGCCAAGCTGTCGCCGCGCGGCCCGCCGTCCA
GCGCCCGGCAAACCCGCTGCCGCACTACCCCAGCCGCGCCATCCAGCCGTGGGTGTCCGCGAAGGTGCCCCGCTGGATGC
CGGTCAGCGTATCGCGTAG

Upstream 100 bases:

>100_bases
GCTCCCCTCCGTGTCCCCAGATTAGGGGACATGAAATTCAACCGACGGTGTCCGATTGGCGGATCGTTTTGGCCGCGCGG
CATATATAGCGTCGTTAATC

Downstream 100 bases:

>100_bases
TGCCATGGTCACCTCACCCGGCTGACCGTCGGCGATTCTGAACTCGCTGGCACCGTGCCGCACCCGCGCGACCGGGGTGA
TGACAGCGGCGGTGCCGCAC

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQ
LRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLA
TGVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWV
HAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVI
AAVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA

Sequences:

>Translated_512_residues
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQ
LRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLA
TGVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWV
HAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVI
AAVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
>Mature_511_residues
PASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQL
RHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLAT
GVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTTY
LLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWVH
AWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIA
AVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRPA
PGKPAAALPQPRHPAVGVREGAPLDAGQRIA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2209_MYCTU (P64953)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   B70786
- RefSeq:   NP_216725.1
- RefSeq:   NP_336737.1
- ProteinModelPortal:   P64953
- EnsemblBacteria:   EBMYCT00000001399
- EnsemblBacteria:   EBMYCT00000069247
- GeneID:   887230
- GeneID:   924160
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2265
- KEGG:   mtu:Rv2209
- TIGR:   MT2265
- TubercuList:   Rv2209
- GeneTree:   EBGT00050000018700
- HOGENOM:   HBG569379
- OMA:   CHASAHR
- ProtClustDB:   CLSK790378
- InterPro:   IPR016196

Pfam domain/function: SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 53580; Mature: 53448

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1974dbc0)-; HASH(0x1b7dd2d8)-; HASH(0x1b1ac038)-; HASH(0x1ba83cd4)-; HASH(0x1a811760)-; HASH(0x1b66cd74)-; HASH(0x1a26269c)-; HASH(0x1b38b774)-; HASH(0x1b346f68)-; HASH(0x1b3e1154)-; HASH(0x1af188b4)-; HASH(0x1b588bdc)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAF
CCHHHHHHHHCCHHHHHHHHHHCCCEEEECEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
CIGAILGNSLSPLILQRAGQLRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLATGVTLVIVPMLAHGNEMARY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
HDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSA
HHHHHHHHHCCHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNAAAALLCMVAESCGQWVHAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
CVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIAAVASLRAPTRIGVTADTSP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEECCCCC
QAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
CCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
PASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAF
CHHHHHHHHCCHHHHHHHHHHCCCEEEECEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
CIGAILGNSLSPLILQRAGQLRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLATGVTLVIVPMLAHGNEMARY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
HDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSA
HHHHHHHHHCCHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNAAAALLCMVAESCGQWVHAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
CVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIAAVASLRAPTRIGVTADTSP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEECCCCC
QAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
CCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036