Click here to switch to the map view.

The map label for this gene is rsmA [H]

Identifier: 148823202

GI number: 148823202

Start: 2239934

End: 2240473

Strand: Direct

Name: rsmA [H]

Synonym: TBFG_12019

Alternate gene names: 148823202

Gene position: 2239934-2240473 (Clockwise)

Preceding gene: 148823201

Following gene: 148823210

Centisome position: 50.63

GC content: 70.19

Gene sequence:

>540_bases
GTGTCCGCCCTCGGACGGTCGCGACGGGCATGGGGCTGGCACCGGCTCCATGACGAATGGGCAGCGCGGGTAGTCAGCGC
GGCCGCAGTGCGGCCCGGTGAGCTCGTGTTTGACATCGGCGCCGGCGAAGGGGCACTGACGGCGCATCTAGTGCGAGCGG
GGGCGCGGGTGGTCGCCGTGGAGTTGCACCCGCGACGAGTCGGTGTCCTCCGCGAGCGATTCCCTGGCATTACCGTGGTG
CACGCGGACGCCGCCTCGATCCGGTTGCCCGGCCGGCCGTTCCGGGTTGTGGCGAACCCGCCGTACGGGATTTCGTCCCG
CCTGCTGCGGACGCTGCTGGCACCCAACAGCGGGCTTGTCGCGGCCGATCTCGTGCTGCAGCGAGCCCTCGTATGTAAAT
TCGCTTCTCGCAACGCGCGAAGGTTCACCCTGACCGTCGGCCTCATGCTGCCACGGCGCGCGTTCCTGCCACCGCCGCAT
GTGGATTCCGCGGTGCTCGTCGTCCGCCGCCGGAAGTGCGGTGACTGGCAGGGGCGGTAA

Upstream 100 bases:

>100_bases
GATGACCAGAAGGTTGCCTGAACCGAGAAATTGGATTGATCGCAGTGCCGGTGGCGGGCTACGGTCGGGCGCGTGGGCAT
CTACGCAGTGACGGTACGTC

Downstream 100 bases:

>100_bases
ACCCGCGGCCGCCAGTAGGTGTACCACCTTTGCTAGAAGTGGCACACTTCGTTCTATGTCGACCACTCGTCCGCGCTACC
AAATAACCGAAACCCCGGAG

Product: methyltransferase

Products: NA

Alternate protein names: 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAVELHPRRVGVLRERFPGITVV
HADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLVAADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPH
VDSAVLVVRRRKCGDWQGR

Sequences:

>Translated_179_residues
MSALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAVELHPRRVGVLRERFPGITVV
HADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLVAADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPH
VDSAVLVVRRRKCGDWQGR
>Mature_178_residues
SALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAVELHPRRVGVLRERFPGITVVH
ADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLVAADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPHV
DSAVLVVRRRKCGDWQGR

Specific function: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 19606; Mature: 19475

Theoretical pI: Translated: 12.41; Mature: 12.41

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEE
ELHPRRVGVLRERFPGITVVHADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLV
EECCHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCH
AADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPHVDSAVLVVRRRKCGDWQGR
HHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHEEEHHCCCCCCCC
>Mature Secondary Structure 
SALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEE
ELHPRRVGVLRERFPGITVVHADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLV
EECCHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCH
AADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPHVDSAVLVVRRRKCGDWQGR
HHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHEEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Dimethylation [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]