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The map label for this gene is ybeX [C]

Identifier: 148823053

GI number: 148823053

Start: 2098914

End: 2100281

Strand: Reverse

Name: ybeX [C]

Synonym: TBFG_11870

Alternate gene names: 148823053

Gene position: 2100281-2098914 (Counterclockwise)

Preceding gene: 148823054

Following gene: 148823052

Centisome position: 47.47

GC content: 67.25

Gene sequence:

>1368_bases
GTGAACCTCACCGATACCGTCGCCACCATCCTGGCGATCTTGGCGCTCACCGCAGGCACGGGGGTGTTCGTCGCGGCCGA
ATTCTCGCTGACCGCGCTGGACCGCAGCACCGTGGAGGCCAACGCCCGCGGCGGCACCAGTCGGGACCGCTTCATCCAGC
GCGCACACCACCGGCTGTCGTTCCAGCTTTCGGGTGCTCAGTTGGGTATCTCGATCACCACCTTGGCTACCGGCTACCTG
ACCGAACCGCTGGTGGCCGAGCTACCGCATCCTGGGCTGGTCGCAGTCGGAATGTCTGATCGGGTGGCCGACGGTCTTAT
CACGTTTTTTGCCCTGGTGATCGTGACATCGCTGTCGATGGTCTTCGGCGAGCTGGTCCCCAAGTATCTCGCGGTGGCGC
GCCCGCTGCGCACCGCGCGCTCAGTCGTGGCCGGCCAGGTGCTGTTCTCACTGCTGCTCACCCCGGCCATCCGTCTCACG
AACGGAGCGGCGAACTGGATCGTGCGTCGACTTGGCATCGAGCCGGCCGAGGAGCTGCGCTCAGCTCGCACACCGCAGGA
GCTGGTGTCGTTGGTGCGTAGTTCCGCGCGCAGCGGCGCACTCGATGACGCCACGGCGTGGCTGATGCGCCGCTCGCTGC
AGTTCGGCGCCCTGACGGCCGAGGAGCTGATGACGCCACGGTCGAAGATCGTGGCGCTGCAGACCGATGACACCATCGCC
GACCTGGTTGCGGCCGCGGCCGCATCGGGATTCTCGCGCTTCCCGGTGGTCGAGGGAGATCTCGATGCGACCGTCGGCAT
CGTGCACGTCAAGCAGGTGTTCGAGGTTCCGCCCGGCGATCGCGCGCACACGCTGCTAACGACGGTCGCCGAGCCGGTCG
CGGTGGTGCCCTCGACGCTCGACGGCGATGCGGTGATGGCGCAGGTCCGCGCCAGTGCGCTACAGACCGCCATGGTTGTG
GACGAGTACGGCGGCACCGCGGGCATGGTAACCCTGGAGGACTTGATCGAAGAGATCGTGGGCGACGTCCGCGACGAACA
CGACGATGCGACACCGGATGTGGTGGCAGCCGGCAACGGATGGCGGGTCTCGGGTCTGCTACGCATCGACGAGGTGGCCA
GCGCCACCGGCTATCGAGCCCCCGACGGTCCGTACGAGACGATCGGCGGGTTGGTGCTTCGAGAGCTCGGCCACATCCCG
GTGGCCGGCGAAACGGTCGAGCTGACTGCCTTGGACCAGGACGGACTTCCCGACGACTCGATGCGGTGGTTAGCCACCGT
GATCCAGATGGACGGGCGCCGGATCGACTTGTTGGAGTTGATCAAAATGGGCGGCCATGCCGACCCCGGGTCGGGGCGGG
GCCGCTGA

Upstream 100 bases:

>100_bases
AAAGGGATGACGTGCCGCGGGCACCCGTCCACACCGTCGGTTTTCCAGGCGAGCGGCCGGTACTGGCTCGGCCCGATATA
GCGCGACGACCGAGCCGCCC

Downstream 100 bases:

>100_bases
TGGATGTGCTGTCCGCGGTGTTGCTGGCGCTTTTGCTGATCGGCGCCAACGCGTTCTTCGTGGGCGCGGAATTCGCGTTG
ATCTCGGCGCGTCGTGACCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYL
TEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLT
NGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA
DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVV
DEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIP
VAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR

Sequences:

>Translated_455_residues
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYL
TEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLT
NGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA
DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVV
DEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIP
VAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
>Mature_455_residues
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYL
TEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLT
NGAANWIVRRLGIEPAEELRSARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA
DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTLDGDAVMAQVRASALQTAMVV
DEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIP
VAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=403, Percent_Identity=28.287841191067, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI94681046, Length=350, Percent_Identity=22.5714285714286, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786879, Length=228, Percent_Identity=29.8245614035088, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693175, Length=319, Percent_Identity=24.4514106583072, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790664, Length=443, Percent_Identity=22.3476297968397, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788119, Length=247, Percent_Identity=27.1255060728745, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082033, Length=388, Percent_Identity=22.9381443298969, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1842_MYCTU (Q50592)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   B70664
- RefSeq:   NP_216358.1
- RefSeq:   NP_336347.1
- ProteinModelPortal:   Q50592
- EnsemblBacteria:   EBMYCT00000000717
- EnsemblBacteria:   EBMYCT00000070150
- GeneID:   885739
- GeneID:   923726
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1890
- KEGG:   mtu:Rv1842c
- TIGR:   MT1890
- TubercuList:   Rv1842c
- GeneTree:   EBGT00050000016975
- HOGENOM:   HBG673071
- OMA:   NGTANWI
- ProtClustDB:   CLSK791426
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 48125; Mature: 48125

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x191aa36c)-; HASH(0x1a76b44c)-; HASH(0x1b08e2d0)-; HASH(0x1b11abf0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLS
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHCCHHHCCCCCCCCHHHHHHHHHHHHHE
FQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSM
EEECCCEECEEEEHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
VFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
SARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA
HCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHEEEEECCCHHH
DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTL
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCC
DGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNG
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCC
WRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDS
EEEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHH
MRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
HHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure
MNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLS
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHCCHHHCCCCCCCCHHHHHHHHHHHHHE
FQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSM
EEECCCEECEEEEHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
VFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
SARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA
HCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHEEEEECCCHHH
DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTL
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCC
DGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNG
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCC
WRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDS
EEEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHH
MRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR
HHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036