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The map label for this gene is hisC [H]

Identifier: 148822807

GI number: 148822807

Start: 1796287

End: 1797429

Strand: Direct

Name: hisC [H]

Synonym: TBFG_11616

Alternate gene names: 148822807

Gene position: 1796287-1797429 (Clockwise)

Preceding gene: 148822806

Following gene: 148822808

Centisome position: 40.6

GC content: 62.99

Gene sequence:

>1143_bases
ATGACCAGGTCCGGACACCCGGTTACATTGGACGACTTGCCGCTGCGCGCCGACTTGCGTGGTAAAGCACCATACGGTGC
ACCGCAATTAGCTGTTCCGGTACGGCTGAACACCAACGAGAACCCGCACCCGCCTACCCGGGCGCTGGTTGACGACGTGG
TGCGATCGGTGCGGGAAGCGGCCATCGACTTGCACCGCTACCCCGACCGCGACGCCGTGGCTCTGCGTGCTGACTTGGCC
GGCTATCTCACCGCGCAGACCGGAATCCAGCTTGGTGTCGAAAACATATGGGCTGCCAACGGTTCCAATGAGATTCTGCA
GCAACTGTTACAGGCGTTTGGCGGTCCGGGGCGTAGCGCGATCGGTTTCGTACCGTCCTATTCGATGCACCCGATCATCT
CCGACGGCACCCACACGGAATGGATCGAGGCGTCCCGCGCCAATGACTTCGGTCTCGACGTGGACGTCGCCGTCGCGGCT
GTGGTCGATCGCAAACCCGATGTGGTGTTCATTGCTAGCCCTAACAACCCGTCCGGACAAAGTGTTTCGTTACCTGACCT
GTGTAAGCTGCTGGACGTTGCGCCCGGAATTGCGATCGTCGACGAGGCCTACGGCGAGTTCTCCTCGCAGCCCAGCGCGG
TGTCGCTGGTCGAGGAGTATCCGAGCAAGCTCGTCGTCACGCGCACCATGAGCAAGGCATTCGCTTTCGCCGGCGGCAGG
CTCGGATACCTGATCGCTACGCCCGCGGTGATCGACGCAATGCTGCTGGTGCGGTTGCCGTATCACCTGTCGTCGGTCAC
TCAAGCCGCGTCCCGGGCCGCGCTGCGGCACTCCGACGACACCTTGAGCAGTGTCGCCGCACTGATCGCCGAACGCGAAC
GCGTAACAACCTCATTGAACGACATGGGTTTTCGAGTCATCCCAAGCGATGCCAACTTCGTGTTGTTCGGCGAGTTTGCC
GATGCGCCGGCCGCCTGGCGGCGCTATCTGGAGGCCGGCATTTTGATCCGCGACGTTGGGATTCCCGGCTATCTGCGGGC
CACCACCGGGCTGGCTGAGGAGAACGATGCGTTCCTGCGGGCAAGCGCCCGGATCGCCACCGACCTGGTCCCCGTCACCC
GCAGTCCTGTAGGAGCGCCATGA

Upstream 100 bases:

>100_bases
CGGAGGCGGCCCTCAAAGACGTTTCCGGACACGTGATCACGCTCGCCACGGCCGAGGACTTGCCGGCGCACGGTGAGGCG
GTACGGCGGAGGTTCGAGCG

Downstream 100 bases:

>100_bases
CAACCACCCAGACAGCCAAAGCTAGCCGGCGGGCGCGTATCGAACGGCGTACCCGCGAATCCGATATCGTCATCGAGCTC
GACCTTGACGGTACCGGGCA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLA
GYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAA
VVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGR
LGYLIATPAVIDAMLLVRLPYHLSSVTQAASRAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFA
DAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP

Sequences:

>Translated_380_residues
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLA
GYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAA
VVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGR
LGYLIATPAVIDAMLLVRLPYHLSSVTQAASRAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFA
DAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
>Mature_379_residues
TRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAG
YLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAV
VDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRL
GYLIATPAVIDAMLLVRLPYHLSSVTQAASRAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFAD
APAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=374, Percent_Identity=32.0855614973262, Blast_Score=136, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322075, Length=355, Percent_Identity=26.7605633802817, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40597; Mature: 40466

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREA
CCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSA
HHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHHCCCCCCC
IGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQ
EECCCCCCCCCEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCC
SVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGR
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCC
LGYLIATPAVIDAMLLVRLPYHLSSVTQAASRAALRHSDDTLSSVAALIAERERVTTSLN
EEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLR
HCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCEEHHHCCCCCCCCHHHH
ASARIATDLVPVTRSPVGAP
HHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREA
CCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSA
HHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHHCCCCCCC
IGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQ
EECCCCCCCCCEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCC
SVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGR
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCC
LGYLIATPAVIDAMLLVRLPYHLSSVTQAASRAALRHSDDTLSSVAALIAERERVTTSLN
EEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLR
HCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCEEHHHCCCCCCCCHHHH
ASARIATDLVPVTRSPVGAP
HHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]