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The map label for this gene is celR [H]

Identifier: 148663439

GI number: 148663439

Start: 4025755

End: 4026834

Strand: Reverse

Name: celR [H]

Synonym: MRA_3614

Alternate gene names: 148663439

Gene position: 4026834-4025755 (Counterclockwise)

Preceding gene: 148663443

Following gene: 148663437

Centisome position: 91.11

GC content: 67.69

Gene sequence:

>1080_bases
GTGAGTCCCACACCGCGGAGGCGGGCGACTCTGGCGTCGTTAGCAGCCGAGCTCAAGGTGTCCCGCACCACTGTCTCGAA
TGCTTTTAACCGACCGGATCAGCTCTCCGCCGATCTACGTGAACGAGTGCTTGCCACGGCCAAGCGACTGGGCTATGCCG
GACCGGATCCGGTGGCGCGATCGTTGCGGACCCGCAAAGCCGGTGCGGTCGGTTTGGTGATGGCCGAACCGCTGACCTAT
TTCTTCAGCGACCCGGCCGCGCGGGATTTTGTTGCGGGAGTGGCGCAGTCGTGCGAAGAGCTGGGGCAGGGCCTGCAGCT
GGTTTCCGTCGGCTCCAGTCGGAGCCTTGCGGACGGCACAGCTGCCGTGCTCGGCGCTGGGGTGGACGGCTTCGTGGTGT
ATTCGGTAGGCGACGACGATCCCTACCTGCAGGTCGTGCTGCAGCGGCGGCTGCCGGTGGTGGTGGTCGACCAGCCCAAA
GACCTCTCCGGAGTGTCCCGGGTCGGCATCGACGACCGGGCGGCGATGCGTGAGCTTGCCGGCTACGTACTCGGGTTGGG
GCATCGCGAGCTCGGCCTGCTGACCATGCGGCTGGGACGGGATCGGCGGCAAGACTTGGTGGACGCCGAGCGGCTGCGGT
CGCCGACCTTCGACGTACAGCGCGAACGCATCGTCGGCGTATGGGAGGCGATGACGGCCGCCGGCGTCGACCCGGACTCG
CTGACCGTGGTGGAAAGCTACGAGCATTTGCCGACGTCCGGCGGCACTGCCGCCAAGGTGGCTCTGCAGGCCAATCCGCG
GCTGACCGCGCTGATGTGCACAGCGGACATCTTGGCGCTCTCAGCTATGGATTACCTTCGGGCGCACGGGATTTACGTGC
CCGGGCAGATGACCGTCACAGGGTTTGACGGAGTGCCAGAGGCGCTGAGCCGGGGGCTGACCACGGTCGCGCAGCCGAGT
CTGCACAAGGGGCACCGGGCGGGCGAGCTATTGCTGAAGCCGCCGCGGTCCGGACTGCCCGTCATCGAGGTGCTCGATAC
CGAGCTGGTCCGGGGCCGCACCGCGGGTCCGCCGGCGTAA

Upstream 100 bases:

>100_bases
ACGATTCATGAACGAGGGGTCGTCACCAACGTCGAAACCGACGGTTGCCAGCCGGCCCACGATATTGCGTGCTCGAGGGT
CCGCTGTACCCTCACCGAAC

Downstream 100 bases:

>100_bases
GTCTTCTAGGCGCTGTCTTGATCGCCGATCAGCAGCCGCACGGCCAGGTCCAGCCGCTTGCTGACGTCGGTAGCCGAGGC
TCGTCGGGTAAGCCACGCGA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTY
FFSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPK
DLSGVSRVGIDDRAAMRELAGYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVTGFDGVPEALSRGLTTVAQPS
LHKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA

Sequences:

>Translated_359_residues
MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTY
FFSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPK
DLSGVSRVGIDDRAAMRELAGYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVTGFDGVPEALSRGLTTVAQPS
LHKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA
>Mature_358_residues
SPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYF
FSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPKD
LSGVSRVGIDDRAAMRELAGYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDSL
TVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVTGFDGVPEALSRGLTTVAQPSL
HKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=27.5757575757576, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790369, Length=335, Percent_Identity=25.6716417910448, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994940, Length=330, Percent_Identity=24.8484848484848, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=27.2455089820359, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789068, Length=303, Percent_Identity=23.7623762376238, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38210; Mature: 38079

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGT
HHHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCH
AAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPKDLSGVSRVGIDDRAAMRELA
HHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHH
GYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVT
EEEEHHHHHCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCEECCCEEEEE
GFDGVPEALSRGLTTVAQPSLHKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA
CCCCCHHHHHCCCHHHCCCCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SPTPRRRATLASLAAELKVSRTTVSNAFNRPDQLSADLRERVLATAKRLGYAGPDPVAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGVAQSCEELGQGLQLVSVGSSRSLADGT
HHHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCH
AAVLGAGVDGFVVYSVGDDDPYLQVVLQRRLPVVVVDQPKDLSGVSRVGIDDRAAMRELA
HHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHH
GYVLGLGHRELGLLTMRLGRDRRQDLVDAERLRSPTFDVQRERIVGVWEAMTAAGVDPDS
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRAHGIYVPGQMTVT
EEEEHHHHHCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCEECCCEEEEE
GFDGVPEALSRGLTTVAQPSLHKGHRAGELLLKPPRSGLPVIEVLDTELVRGRTAGPPA
CCCCCHHHHHCCCHHHCCCCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]