| Definition | Mycobacterium tuberculosis H37Ra, complete genome. |
|---|---|
| Accession | NC_009525 |
| Length | 4,419,977 |
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The map label for this gene is fabG [H]
Identifier: 148663422
GI number: 148663422
Start: 4008313
End: 4009101
Strand: Reverse
Name: fabG [H]
Synonym: MRA_3598
Alternate gene names: 148663422
Gene position: 4009101-4008313 (Counterclockwise)
Preceding gene: 148663423
Following gene: 148663420
Centisome position: 90.7
GC content: 69.2
Gene sequence:
>789_bases ATGAACCTGTCCGTAGCGCCGAAAGAGATTGCCGGACATGGACTTCTGGATGGCAAGGTGGTCGTCGTGACGGCGGCTGC GGGCACCGGCATCGGTTCGGCCACCGCGCGGCGAGCCTTGGCGGAGGGCGCCGACGTGGTGATCTCGGACCACCATGAAC GACGGCTGGGGGAGACGGCCGCCGAGTTGTCTGCGCTGGGGCTGGGCCGGGTGGAGCATGTGGTGTGCGACGTGACGTCC ACCGCCCAGGTCGACGCGCTGATCGACTCGACCACCGCCCGGATGGGCCGGCTCGACGTGCTGGTCAACAACGCCGGGCT GGGCGGGCAGACGCCGGTGGCCGACATGACCGACGACGAGTGGGACCGCGTGTTAGACGTGAGCCTGACGTCGGTGTTCC GGGCCACCCGGGCCGCATTGCGCTACTTCCGCGACGCGCCGCATGGCGGGGTGATCGTCAACAACGCCAGCGTGCTGGGC TGGCGGGCCCAGCATTCGCAGTCGCACTATGCCGCCGCCAAGGCCGGGGTGATGGCGTTGACCCGGTGCAGCGCAATCGA AGCCGCCGAGTATGGGGTGCGGATCAACGCCGTCTCGCCCAGCATCGCCCGGCACAAGTTCCTGGACAAGACCGCCTCGG CCGAGCTGCTGGACCGGCTGGCGGCCGGCGAGGCGTTCGGCCGGGCCGCCGAGCCCTGGGAGGTGGCGGCCACCATCGCG TTTCTGGCCAGCGACTACTCGAGTTACCTGACTGGTGAGGTGATTTCGGTATCCTGCCAGCACCCGTGA
Upstream 100 bases:
>100_bases ATCTATTCACCCGCGCCGACACCATCTACGGAGGATCCAACGAGATCCAGCGCAACATCATCGCCGAGCGGGTGCTCGGT CTGCCCCGGGAGGCCAAGGG
Downstream 100 bases:
>100_bases GTGTCGCGCTACCCCAACAGCTGGCGCAGGTTGAACAACCCCGATATGGCGGTGCCCATGTTAAACAGGCCCGTGTTCAA GCCGCTCCGGACGGAGCCAA
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 262; Mature: 262
Protein sequence:
>262_residues MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTS TAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLG WRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSCQHP
Sequences:
>Translated_262_residues MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTS TAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLG WRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSCQHP >Mature_262_residues MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTS TAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLG WRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSCQHP
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=30.0395256916996, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI15277342, Length=239, Percent_Identity=32.2175732217573, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI59889578, Length=218, Percent_Identity=32.5688073394495, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=31.7073170731707, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=29.2, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=31.0880829015544, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=30, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=27.734375, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=32.3699421965318, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI40254992, Length=182, Percent_Identity=30.2197802197802, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4503301, Length=219, Percent_Identity=26.9406392694064, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.2490118577075, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI40254986, Length=217, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=8e-12, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=34.8178137651822, Blast_Score=127, Evalue=9e-31, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=33.6032388663968, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=36.9477911646586, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=28.7449392712551, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1788459, Length=238, Percent_Identity=28.9915966386555, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI2367175, Length=235, Percent_Identity=29.7872340425532, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=25.5060728744939, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=31.3492063492063, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=32.5581395348837, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=33.0708661417323, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=33.739837398374, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=32.2834645669291, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=31.1284046692607, Blast_Score=113, Evalue=9e-26, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=31.9672131147541, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=32.6996197718631, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=32.5757575757576, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=33.206106870229, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=34.5098039215686, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.9236947791165, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=32.8125, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=30.7984790874525, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=29.0196078431373, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=33.0827067669173, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=29.6992481203008, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=31.9066147859922, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=31.8007662835249, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17551412, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=29.0155440414508, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=27.710843373494, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=30.078125, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=29.6875, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=29.8039215686275, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17544670, Length=253, Percent_Identity=29.6442687747036, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=28.0632411067194, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=210, Percent_Identity=32.3809523809524, Blast_Score=95, Evalue=1e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=24.8995983935743, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=29.7029702970297, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21357041, Length=239, Percent_Identity=35.5648535564854, Blast_Score=127, Evalue=8e-30, Organism=Drosophila melanogaster, GI28571526, Length=239, Percent_Identity=35.9832635983264, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI24644339, Length=240, Percent_Identity=34.5833333333333, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=34.8178137651822, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=32.8, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644337, Length=190, Percent_Identity=34.7368421052632, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.7959183673469, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24665243, Length=187, Percent_Identity=32.0855614973262, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331218, Length=187, Percent_Identity=32.0855614973262, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007236, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24641232, Length=217, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584752, Length=177, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007238, Length=239, Percent_Identity=24.2677824267782, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI221331216, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21357673, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI281364892, Length=163, Percent_Identity=30.6748466257669, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI28571387, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27430; Mature: 27430
Theoretical pI: Translated: 6.03; Mature: 6.03
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETA CCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH AELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDE HHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCH WDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMAL HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHCCCCHHHHHHHHHHHH TRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIA HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSCQHP HHHHHHHHHHCCEEEEEEECCC >Mature Secondary Structure MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETA CCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH AELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDE HHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCH WDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMAL HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEHHCCCCHHHHHHHHHHHH TRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIA HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSCQHP HHHHHHHHHHCCEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]