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The map label for this gene is fadE29 [H]

Identifier: 148663406

GI number: 148663406

Start: 3990643

End: 3991806

Strand: Reverse

Name: fadE29 [H]

Synonym: MRA_3582

Alternate gene names: 148663406

Gene position: 3991806-3990643 (Counterclockwise)

Preceding gene: 148663407

Following gene: 148663405

Centisome position: 90.31

GC content: 64.86

Gene sequence:

>1164_bases
ATGTTCATTGACCTGACGCCGGAGCAGCGCCAGCTGCAAGCCGAGATACGGCAATACTTTTCGAATCTCATCTCGCCCGA
CGAGCGCACGGAGATGGAGAAAGACCGGCACGGCCCGGCCTACCGTGCGGTGATACGGCGCATGGGCCGGGACGGCAGGC
TCGGTGTTGGGTGGCCGAAAGAGTTCGGCGGTCTGGGTTTTGGTCCGATCGAGCAGCAGATCTTCGTCAACGAGGCCCAT
CGCGCCGACGTGCCGCTGCCCGCGGTGACGCTGCAGACCGTCGGCCCCACGCTGCAGGCGCACGGCAGCGAGCTGCAGAA
GAAGAAGTTCCTGCCGGCGATCCTGGCCGGTGAGGCGCACTTCGCGATCGGCTACACCGAGCCGGAAGCCGGCACCGACC
TGGCGTCGTTGCGCACCACCGCCGTTCGCGACGGCGACCACTACATCGTCAACGGCCAGAAGGTCTTCACCACCGGCGCA
CACGACGCCGACTACATCTGGCTGGCCTGCCGCACCGACCCGAATGCCGCTAAGCACAAAGGCATTTCCATTCTAATCGT
CGACACCAAGGATCCCGGCTATTCCTGGACGCCGATCATCTTGGCCGACGGCGCCCACCACACCAATGCCACGTACTACA
ACGACGTGCGCGTGCCGGTCGACATGCTGGTCGGAAAGGAGAACGACGGCTGGCGGCTGATCACCACCCAACTCAACAAC
GAACGGGTAATGCTCGGCCCGGCCGGGCGGTTCGCCAGCATCTACGACCGGGTGCACGCGTGGGCGTCCGTGCCGGGTGG
CAACGGCGTGACGCCGATCGACCACGACGACGTCAAGCGGGCTCTTGGTGAGATTCGTGCGATCTGGCGGATCAACGAGT
TGCTCAACTGGCAGGTAGCGTCCGCCGGTGAGGACATCAACATGGCCGATGCCGCGGCCACGAAAGTCTTTGGCACCGAG
CGTGTTCAGCGTGCCGGCCGGCTCGCCGAGGAAATCGTTGGCAAGTACGGCAACCCCGCCGAACCCGACACCGCCGAGCT
ACTGCGCTGGCTGGACGCCCAGACCAAGCGCAACCTGGTGATCACCTTCGGCGGGGGTGTGAACGAAGTCATGCGCGAGA
TGATCGCCGCGTCTGGCCTCAAAGTGCCAAGGGTGCCCAGGTGA

Upstream 100 bases:

>100_bases
TGGACGTCACGTATCCGATGCACCGCTACTACTCCACGATCAAGGACCTCACCCGGCTGCTGGGCGGGCCCTCGCATCGC
CTTGAGCTCCTGGGAGCGCG

Downstream 100 bases:

>100_bases
CCGGGGTGAGCGACATTCAGGAAGCGGTTGCCCAGATCAAGGCGGCCGGGCCCAGCAAGCCGCGCCTGGCCCGTGACCCG
GTGAACCAGCCGATGATCAA

Product: acyl-CoA dehydrogenase FadE29

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPKEFGGLGFGPIEQQIFVNEAH
RADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAHFAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGA
HDADYIWLACRTDPNAAKHKGISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNN
ERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVASAGEDINMADAAATKVFGTE
RVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLVITFGGGVNEVMREMIAASGLKVPRVPR

Sequences:

>Translated_387_residues
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPKEFGGLGFGPIEQQIFVNEAH
RADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAHFAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGA
HDADYIWLACRTDPNAAKHKGISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNN
ERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVASAGEDINMADAAATKVFGTE
RVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLVITFGGGVNEVMREMIAASGLKVPRVPR
>Mature_387_residues
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPKEFGGLGFGPIEQQIFVNEAH
RADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAHFAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGA
HDADYIWLACRTDPNAAKHKGISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNN
ERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVASAGEDINMADAAATKVFGTE
RVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLVITFGGGVNEVMREMIAASGLKVPRVPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=268, Percent_Identity=29.8507462686567, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=25.9842519685039, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI226958414, Length=227, Percent_Identity=31.2775330396476, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI7656849, Length=403, Percent_Identity=26.7990074441687, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4557231, Length=360, Percent_Identity=25.5555555555556, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI187960098, Length=360, Percent_Identity=25.5555555555556, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI76496475, Length=355, Percent_Identity=27.0422535211268, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4557235, Length=355, Percent_Identity=27.0422535211268, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI21361497, Length=402, Percent_Identity=23.6318407960199, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4501859, Length=259, Percent_Identity=26.2548262548263, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4557233, Length=345, Percent_Identity=23.768115942029, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=26.5625, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=26.246719160105, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17508101, Length=357, Percent_Identity=24.9299719887955, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=360, Percent_Identity=23.8888888888889, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=362, Percent_Identity=22.9281767955801, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=326, Percent_Identity=25.4601226993865, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=23.3933161953728, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=24.1847826086957, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=25.5936675461741, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=24.4031830238727, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=24.4525547445255, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=252, Percent_Identity=26.984126984127, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=255, Percent_Identity=25.0980392156863, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363737, Length=396, Percent_Identity=24.7474747474747, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=25.1968503937008, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356377, Length=389, Percent_Identity=24.6786632390745, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24660351, Length=362, Percent_Identity=25.1381215469613, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666513, Length=244, Percent_Identity=26.2295081967213, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646207, Length=244, Percent_Identity=28.2786885245902, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42716; Mature: 42716

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPK
CEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCH
EFGGLGFGPIEQQIFVNEAHRADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAH
HHCCCCCCCCCHHHEECCCCCCCCCCCEEEHHHCCCCHHHCCHHHHHHHCCCHHEECCCE
FAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGAHDADYIWLACRTDPNAAKHK
EEEEECCCCCCCCHHHHHHHEEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCHHHHC
GISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNN
CEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHEEECCCCCCEEEEEEECC
ERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEE
SAGEDINMADAAATKVFGTERVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEE
ITFGGGVNEVMREMIAASGLKVPRVPR
EEECCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFIDLTPEQRQLQAEIRQYFSNLISPDERTEMEKDRHGPAYRAVIRRMGRDGRLGVGWPK
CEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCH
EFGGLGFGPIEQQIFVNEAHRADVPLPAVTLQTVGPTLQAHGSELQKKKFLPAILAGEAH
HHCCCCCCCCCHHHEECCCCCCCCCCCEEEHHHCCCCHHHCCHHHHHHHCCCHHEECCCE
FAIGYTEPEAGTDLASLRTTAVRDGDHYIVNGQKVFTTGAHDADYIWLACRTDPNAAKHK
EEEEECCCCCCCCHHHHHHHEEECCCEEEECCCEEEEECCCCCCEEEEEEECCCCHHHHC
GISILIVDTKDPGYSWTPIILADGAHHTNATYYNDVRVPVDMLVGKENDGWRLITTQLNN
CEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHEEECCCCCCEEEEEEECC
ERVMLGPAGRFASIYDRVHAWASVPGGNGVTPIDHDDVKRALGEIRAIWRINELLNWQVA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEE
SAGEDINMADAAATKVFGTERVQRAGRLAEEIVGKYGNPAEPDTAELLRWLDAQTKRNLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEE
ITFGGGVNEVMREMIAASGLKVPRVPR
EEECCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]