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The map label for this gene is ppe62

Identifier: 148663396

GI number: 148663396

Start: 3979371

End: 3981119

Strand: Reverse

Name: ppe62

Synonym: MRA_3572

Alternate gene names: 148663396

Gene position: 3981119-3979371 (Counterclockwise)

Preceding gene: 148663397

Following gene: 148663394

Centisome position: 90.07

GC content: 65.81

Gene sequence:

>1749_bases
ATGAACTATGCGGTATTGCCGCCGGAGCTTAATTCGTTGCGGATGTTCACGGGTGCAGGTTCGGCGCCGATGTTGGCGGC
GGCGGTGGCCTGGGACGGGCTGGCCGCAGAGTTGGGGTCCGCGGCGTCCTCGTTTGGGTCGGTGACCTCGGACTTGGCAA
GTCAGGCGTGGCAGGGGCCGGCGGCGGCGGCGATGGCGGCGGCGGCGGCACCGTATGCGGGATGGTTGAGCGCTGCGGCG
GCCCGGGCCGCGGGGGCGGCGGCCCAGGCCAAGGCGGTGGCCAGCGCGTTCGAGGCGGCACGGGCGGCGACGGTGCACCC
TTTGCTGGTGGCGGCCAACCGCAATGCGTTTGCGCAGTTGGTGATGTCGAATTGGTTCGGGCTGAACGCGCCGCTGATTG
CGGCCGTTGAGGGCGCCTACGAACAGATGTGGGCCGCGGATGTGGCCGCGATGGTGGGCTACCACTCCGGGGCCTCGGCG
GCGGCCGAGCAGTTGGTGCCCTTTCAGCAGGCGCTGCAGCAGCTGCCGAACCTGGGTATCGGCAATATCGGCAACGCCAA
CCTGGGCGGCGGCAACACCGGCGACCTGAACACCGGCAACGGCAACATCGGTAACACCAACCTGGGCAGCGGGAACCGGG
GTGACGCGAACCTGGGCAGCGGCAACATCGGCAACTCCAACGTGGGCGGCGGGAACGTCGGCAACGGCAACTTCGGCAGC
GGCAACGGGAGGGCGGGACTTCCAGGCAGTGGGAACGTCGGCAACGGGAACCTCGGCAACAGCAACCTGGGCAGCGGCAA
TACCGGCAACTCCAACGTCGGGTTCGGGAATACCGGCAACAACAACGTCGGCACCGGAAACGCCGGCAGCGGCAACATCG
GCGCCGGGAACACCGGCAGCAGCAACTGGGGCTTCGGCAACAACGGCATTGGCAACATCGGTTTCGGCAACACCGGCAAC
GGCAACATCGGCTTCGGGCTCACCGGCAACAACCAGGTGGGCATCGGTGGGCTGAACTCGGGCAGCGGAAACATCGGCTT
GTTCAACTCGGGCACCAACAACGTCGGTTTCTTCAACTCCGGCAACGGCAACCTGGGTATCGGCAACTCCAGCGACGCGA
ATGTGGGCATCGGAAACTCGGGGGCCACCGTGGGCCCGTTCGTGGCGGGCCATAACACCGGTTTCGGGAACTCGGGTTCG
CTCAACACGGGCATGGGAAACGCCGGGGGCGTGAATACCGGTTTCGGAAACGGCGGCGCAATAAACCTCGGCTTCGGGAA
CTCGGGCCAGTTGAATGCGGGCAGCTTCAACGCGGGCAGCATCAACACGGGCAACTTCAATTCCGGACAAGGCAATACCG
GTGATTTCAACGCCGGCGTCAGAAATACCGGCTGGTCAAACTCGGGCCTCACTAACACCGGCGCCTTCAACGCGGGTTCG
CTCAACACCGGGTTCGGCGCCGTCGGCACCGGCTCCGGCCCGAACTCGGGTTTCGGCAACGCCGGCACGAACAACTCGGG
CTTCTTCAACACGGGCGTTGGCAGCTCGGGGTTCCAGAACGGGGGCAGCAACAACTCGGGCCTGCAAAACGCGGTCGGCA
CCGTCATCGCGGCGGGTTTCGGAAACACCGGCGCCCAAACGGTGGGTATCGCAAACTCGGGCGTCTTAAACTCCGGATTC
TTCAACTCGGGCGTCCACAACTCGGGCGGCTTCAACAGCGAGAACCAGCGGTCGGGGTTCGGGAACTGA

Upstream 100 bases:

>100_bases
GACGACACCGCTGGTTCGCGGATTTCACGGAAACGCAGATGGTCCGACCCGGTTTGTCCTACGGTTCTGACTGATTGTCA
GGTCGGGAAGGGACGGGGTC

Downstream 100 bases:

>100_bases
TTTCGCTTTGGTGCGGTATCGAATGCCATAACCGGTGGGGACCCGCTCCAAGCGCGGTTGCGCTACTACTGCAGTCCCAG
TTCGTTGGTGTTGGAAGCGC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MNYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGPAAAAMAAAAAPYAGWLSAAA
ARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSNWFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASA
AAEQLVPFQQALQQLPNLGIGNIGNANLGGGNTGDLNTGNGNIGNTNLGSGNRGDANLGSGNIGNSNVGGGNVGNGNFGS
GNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNNNVGTGNAGSGNIGAGNTGSSNWGFGNNGIGNIGFGNTGN
GNIGFGLTGNNQVGIGGLNSGSGNIGLFNSGTNNVGFFNSGNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGS
LNTGMGNAGGVNTGFGNGGAINLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGS
LNTGFGAVGTGSGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGFGNTGAQTVGIANSGVLNSGF
FNSGVHNSGGFNSENQRSGFGN

Sequences:

>Translated_582_residues
MNYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGPAAAAMAAAAAPYAGWLSAAA
ARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSNWFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASA
AAEQLVPFQQALQQLPNLGIGNIGNANLGGGNTGDLNTGNGNIGNTNLGSGNRGDANLGSGNIGNSNVGGGNVGNGNFGS
GNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNNNVGTGNAGSGNIGAGNTGSSNWGFGNNGIGNIGFGNTGN
GNIGFGLTGNNQVGIGGLNSGSGNIGLFNSGTNNVGFFNSGNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGS
LNTGMGNAGGVNTGFGNGGAINLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGS
LNTGFGAVGTGSGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGFGNTGAQTVGIANSGVLNSGF
FNSGVHNSGGFNSENQRSGFGN
>Mature_582_residues
MNYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGPAAAAMAAAAAPYAGWLSAAA
ARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSNWFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASA
AAEQLVPFQQALQQLPNLGIGNIGNANLGGGNTGDLNTGNGNIGNTNLGSGNRGDANLGSGNIGNSNVGGGNVGNGNFGS
GNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNNNVGTGNAGSGNIGAGNTGSSNWGFGNNGIGNIGFGNTGN
GNIGFGLTGNNQVGIGGLNSGSGNIGLFNSGTNNVGFFNSGNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGS
LNTGMGNAGGVNTGFGNGGAINLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGS
LNTGFGAVGTGSGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGFGNTGAQTVGIANSGVLNSGF
FNSGVHNSGGFNSENQRSGFGN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE62_MYCTU (Q7D5C5)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   F70675
- RefSeq:   NP_338182.1
- RefSeq:   YP_177985.1
- ProteinModelPortal:   Q7D5C5
- SMR:   Q7D5C5
- EnsemblBacteria:   EBMYCT00000000290
- EnsemblBacteria:   EBMYCT00000071502
- GeneID:   888385
- GeneID:   922851
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3637
- KEGG:   mtu:Rv3533c
- TIGR:   MT3637
- TubercuList:   Rv3533c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- OMA:   LSVGPQS
- ProtClustDB:   CLSK799998
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 55504; Mature: 55504

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGP
CCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AAAAMAAAAAPYAGWLSAAAARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
VMSNWFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASAAAEQLVPFQQALQQLPNLGI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GNIGNANLGGGNTGDLNTGNGNIGNTNLGSGNRGDANLGSGNIGNSNVGGGNVGNGNFGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNNNVGTGNAGSGNIGAGNTGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNWGFGNNGIGNIGFGNTGNGNIGFGLTGNNQVGIGGLNSGSGNIGLFNSGTNNVGFFNS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCEEEC
GNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGSLNTGMGNAGGVNTGFGNGGA
CCCCCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
INLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LNTGFGAVGTGSGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHEEECC
GNTGAQTVGIANSGVLNSGFFNSGVHNSGGFNSENQRSGFGN
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNYAVLPPELNSLRMFTGAGSAPMLAAAVAWDGLAAELGSAASSFGSVTSDLASQAWQGP
CCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AAAAMAAAAAPYAGWLSAAAARAAGAAAQAKAVASAFEAARAATVHPLLVAANRNAFAQL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
VMSNWFGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASAAAEQLVPFQQALQQLPNLGI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GNIGNANLGGGNTGDLNTGNGNIGNTNLGSGNRGDANLGSGNIGNSNVGGGNVGNGNFGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNGRAGLPGSGNVGNGNLGNSNLGSGNTGNSNVGFGNTGNNNVGTGNAGSGNIGAGNTGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SNWGFGNNGIGNIGFGNTGNGNIGFGLTGNNQVGIGGLNSGSGNIGLFNSGTNNVGFFNS
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCEEEEECCCCCCCEEEC
GNGNLGIGNSSDANVGIGNSGATVGPFVAGHNTGFGNSGSLNTGMGNAGGVNTGFGNGGA
CCCCCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
INLGFGNSGQLNAGSFNAGSINTGNFNSGQGNTGDFNAGVRNTGWSNSGLTNTGAFNAGS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LNTGFGAVGTGSGPNSGFGNAGTNNSGFFNTGVGSSGFQNGGSNNSGLQNAVGTVIAAGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHEEECC
GNTGAQTVGIANSGVLNSGFFNSGVHNSGGFNSENQRSGFGN
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036