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The map label for this gene is yhaU [H]

Identifier: 148663099

GI number: 148663099

Start: 3622742

End: 3623899

Strand: Reverse

Name: yhaU [H]

Synonym: MRA_3277

Alternate gene names: 148663099

Gene position: 3623899-3622742 (Counterclockwise)

Preceding gene: 148663100

Following gene: 148663097

Centisome position: 81.99

GC content: 65.37

Gene sequence:

>1158_bases
GTGGAGGTTTCGAGGGCGCTGTTGTTTGAGCTCGGCGTCCTGTTGGCGGTGCTTGCGGTGCTGGGTGCAGTGGCACGACG
ATTCGCGTTGTCGCCGATTCCGGTGTATTTGTTGGCGGGTTTGTCGTTAGGCAATGGCGGCATCTTGGGGGTGGCCGCCG
CCGGTGAGTTCATCGCTACCGGTGCGCCCATCGGTGTCGTGTTGTTGCTTTTGGCCCTGGGTCTGGAGTTTTCTGCGACC
GAGTTCGCCAGCAGTCTGCGCCACCACCTGCCGTCGGCGGGTGTCGATATCGTCCTCAACGCCACGCCCGGTGCGGTGGC
GGGCTGGCTTTTGGGGTTGGACGGTGTTGCCATCCTCGGTCTGGCCGGGGTCACCTACATTTCCTCCTCGGGTGTGATCG
CGCGGCTGTTGGAGGACCTGCGTCGGCTCGGCAACCGGGAAACGCCGGCTGTGCTGTCGGTGCTGGTGCTCGAAGACTTC
GCGATGGCGGCCTACTTGCCGCTGTTCGCGGTTCTCGCGACAGACGGCAGCTGGCTCGAGGCGGTCGTGGGCATGACGGT
GGCGATCGCCGCTTTGCTTGGGGCGTTCGCGGCGTCGTATCGTTGGGGTCATCATGTCGGCCGGTTGGTGACTCATCCTG
ATTCCGAACAATTGTTGTTGCGGGTGCTGGGCATCACCTTGATCGTGGCGGCGGTGGCCGAGTCGCTGCACGCGTCGGCG
GCTGTGGGTGCGTTTCTGGTAGGCCTCACGCTTACCGGGGAGACCGCAGACCGGGCACGCATGGTGCTGACTCCGCTGCG
TGACTTGTTCGCCACGATCTTCTTCCTGGGAATCGGCCTGTCGGTTGACCCGGGAAAGCTCGTTTCAATGCTTCCGGTAG
CGCTGGCCCTGGCCGCTGTCACCGCAGCGACCAAGGTGGCCACCGGGATGTTCGCTGCCCGGCGGGAGGGAGTGGCACGG
CGTGGGCAGCTGCGTGCTGGCACCGCGCTCGTTGCCCGGGGGGAGTTTTCTTTGATCATCATCGGGCTGGCCGGTGCCTC
GATCCCGGGGGTTGCCGCCTTGGCCACGGCGTATGTGTTCGTCATGGCGATCGTCGGTCCGATACTGGCCCGCTACACCG
GCGGTGGGCTGCCGGCCGCCGCAGTAGCTTCGAACTAG

Upstream 100 bases:

>100_bases
GGCCCGACTGATGTGCTGCGAGCCGGAGATGTCCTCATCGTGATCGGCACCGAGGACGGGATCGCCGGGGTCGAACAGAT
CGTCGAAAAGGGCTGAACCG

Downstream 100 bases:

>100_bases
GGTGTGGGCCGGCGATCTCACCCGATGTGCAGGGCGACCATCAGCCATCGGGTTTCGTTACCGGCGGGCCGTTGTTCCAC
CCGGCAGGCGATCGCATGGA

Product: putative cation/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSAT
EFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA
AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVAR
RGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN

Sequences:

>Translated_385_residues
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSAT
EFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA
AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVAR
RGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN
>Mature_385_residues
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSAT
EFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDF
AMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA
AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVAR
RGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=344, Percent_Identity=29.6511627906977, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 39076; Mature: 39076

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHC
GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHH
VMAIVGPILARYTGGGLPAAAVASN
HHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHC
GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHH
VMAIVGPILARYTGGGLPAAAVASN
HHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]