Click here to switch to the map view.

The map label for this gene is 148662424

Identifier: 148662424

GI number: 148662424

Start: 2922972

End: 2924645

Strand: Reverse

Name: 148662424

Synonym: MRA_2614

Alternate gene names: NA

Gene position: 2924645-2922972 (Counterclockwise)

Preceding gene: 148662425

Following gene: 148662423

Centisome position: 66.17

GC content: 66.55

Gene sequence:

>1674_bases
GTGGCCCCCCGCCGCCGGCGTCATACGCGCATCGCCGGCCTGCGAGTCGTTGGTACCGCGACGTTGGTCGCCGCAACCAC
GCTGACCGCGTGTTCGGGCAGCGCCGCGGCTCAGATCGACTACGTGGTCGACGGCGCGCTGGTCACCTACAACACCAATA
CCGTCATCGGTGCCGCGTCGGCCGGGGCGCAGGCATTCGCCCGGACTCTCACCGGGTTTGGCTATCACGGCCCCGACGGC
CAAGTGGTGGCTGACCGCGACTTCGGAACGGTCTCGGTGGTGGAGGGGTCGCCGTTGATCCTCGACTACCAGATCTCCGA
CGACGCCGTCTATTCCGACGGCAGGCCGGTGACCTGTGACGACCTGGTATTGGCCTGGGCGGCACAATCCGGCCGCTTTC
CCGGCTTCGACGCTGCTACGCAGGCCGGCTATGTCGACATCGCCAACATCGAGTGCACGGCGGGGCAGAAAAAGGCCCGG
GTGTCGTTCATCCCGGATCGCAGTGTCGTTGACCACTCCCAGCTGTTCACCGCGACGTCGCTGATGCCGTCGCACGTGAT
CGCCGACCAGCTGCACATCGATGTTACCGCGGCGTTGCTAAGCAACAACGTGTCAGCGGTGGAACAGATTGCGCGACTGT
GGAATTCCACGTGGGACCTCAAGCCGGGCCGCAGCCACGACGAAGTCCGCAGCCGCTTCCCCTCGTCGGGACCGTACAAG
ATCGAATCCGTCCTGGACGATGGCGCCGTGGTGCTCGTCGCCAATGATCGTTGGTGGGGCACCAAGGCGATCACGAAGCG
GATCACCGTCTGGCCGCAGGGAGCCGATATCCAAGACCGGGTCAACAACCGCAGCGTCGACGTGGTCGACGTCGCGGCCG
GTTCATCGGGATCCCTGGTAACCCCCGACAGCTACCAGCGCACCGACTACCCGTCGGCCGGGATCGAGCAGCTGATCTTC
GCACCACAAGGTTCACTCGCGCAAAGCCGCACCCGCCGCGCGCTCGCGTTGTGTGTACCCCGGGACGCGATCGCTCGGGA
TGCCGGGGTTCCGATTGCCAACTCGCGGCTGTCCCCGGCGACCGACGATGCCCTCACCGATGCCGACGGCGCCGCCGAAG
CACGTCAGTTCGGCCGGGTGGACCCCGCCGCCGCTCGCGACGCGCTGGGTGGTACGCCGCTGACCGTGCGGATCGGCTAC
GGCAGGCCCAACGCTCGGTTGGCGGCCACCATCGGAACCATTGCCGACGCCTGCGCCCCGGCCGGGATCACCGTTTCGGA
TGTGACGGTGGACACACCCGGACCGCAAGCGCTGCGGGACGGAAAGATTGACGTATTGTTGGCGAGCACCGGTGGGGCCA
CCGGCAGCGGATCGAGCGGATCGTGTGCGATGGATGCCTATGACTTGCACAGCGGCAACGGAAACAATCTATCGGGGTAC
GCAAACGCTCAGATCGACGGCATCATCAGCGCGCTCGCGGTGTCGGCCGACCCCGCCGAGCGGGCCAGGTTGCTTGCCGA
GGCCGCGCCGGTGCTCTGGGATGAGATGCCAACCTTGCCGTTGTACCGGCAGCAGCGCACGTTGTTGATGTCGACGAAAA
TGTATGCGGTGAGCAGGAATCCGACGCGATGGGGGGCAGGGTGGAACATGGATCGCTGGGCGCTGGCGCGGTGA

Upstream 100 bases:

>100_bases
CCCAGGGCTCCAGCAAGCCGGCGCCGGGGGCGCGCCCAGTGCGTCCCGTCGGTACCAGGCGTCCGACCGGCAAGCGGAAC
GCCGGTCGGCGGTAGGCGCG

Downstream 100 bases:

>100_bases
CGATGGCCAGTGCCATCTGCAGGTAATTGACAGAATTCCACGACGAGAAGCGGACCTATCGGAGCGTAGTGTCGCAGGTG
CTCCGGGCTGTCTGGGAGAG

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MAPRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDG
QVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKAR
VSFIPDRSVVDHSQLFTATSLMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYK
IESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIF
APQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGY
GRPNARLAATIGTIADACAPAGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGY
ANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRNPTRWGAGWNMDRWALAR

Sequences:

>Translated_557_residues
MAPRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDG
QVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKAR
VSFIPDRSVVDHSQLFTATSLMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYK
IESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIF
APQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGY
GRPNARLAATIGTIADACAPAGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGY
ANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
>Mature_556_residues
APRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQ
VVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKARV
SFIPDRSVVDHSQLFTATSLMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYKI
ESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFA
PQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGYG
RPNARLAATIGTIADACAPAGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGYA
NAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRNPTRWGAGWNMDRWALAR

Specific function: Unknown

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.bovis Mb2616c and M.leprae ML0489

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2585_MYCTU (Q50636)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   H70725
- RefSeq:   NP_217101.1
- RefSeq:   NP_337161.1
- ProteinModelPortal:   Q50636
- EnsemblBacteria:   EBMYCT00000003818
- EnsemblBacteria:   EBMYCT00000069719
- GeneID:   887701
- GeneID:   925653
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2662
- KEGG:   mtu:Rv2585c
- TIGR:   MT2662
- TubercuList:   Rv2585c
- GeneTree:   EBGT00050000016139
- HOGENOM:   HBG564678
- OMA:   WNMDRWV
- ProtClustDB:   CLSK791940
- GO:   GO:0005829
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 58635; Mature: 58504

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAAS
CCCCHHHHHHHEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCEEEEECC
AGAQAFARTLTGFGYHGPDGQVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCD
CCHHHHHHHHHCCCEECCCCCEEEECCCCEEEEECCCCEEEEEEECCCCEECCCCCCCHH
DLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATS
HHHHEEECCCCCCCCCCHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHH
LMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYK
CCCHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEE
IESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLV
EEEECCCCEEEEEECCCCCCCHHHHEEEEECCCCCCHHHHCCCCCEEEEEEECCCCCCEE
TPDSYQRTDYPSAGIEQLIFAPQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPA
CCCCCCCCCCCCCCHHHEEECCCCCHHHHHHHCEEEEECCCHHHHHHCCCCCCCCCCCCC
TDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAP
CCCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHHCC
AGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGY
CCCEEEEEEECCCCCHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCE
ANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRN
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEEEEEECC
PTRWGAGWNMDRWALAR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAAS
CCCHHHHHHHEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCEEEEECC
AGAQAFARTLTGFGYHGPDGQVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCD
CCHHHHHHHHHCCCEECCCCCEEEECCCCEEEEECCCCEEEEEEECCCCEECCCCCCCHH
DLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATS
HHHHEEECCCCCCCCCCHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHH
LMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYK
CCCHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEE
IESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLV
EEEECCCCEEEEEECCCCCCCHHHHEEEEECCCCCCHHHHCCCCCEEEEEEECCCCCCEE
TPDSYQRTDYPSAGIEQLIFAPQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPA
CCCCCCCCCCCCCCHHHEEECCCCCHHHHHHHCEEEEECCCHHHHHHCCCCCCCCCCCCC
TDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAP
CCCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCCCEEEEHHHHHHHHHCC
AGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGY
CCCEEEEEEECCCCCHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCE
ANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRN
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEEEEEECC
PTRWGAGWNMDRWALAR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036