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The map label for this gene is yfmR [H]

Identifier: 148661464

GI number: 148661464

Start: 1895742

End: 1896860

Strand: Reverse

Name: yfmR [H]

Synonym: MRA_1679

Alternate gene names: 148661464

Gene position: 1896860-1895742 (Counterclockwise)

Preceding gene: 148661468

Following gene: 148661463

Centisome position: 42.92

GC content: 68.36

Gene sequence:

>1119_bases
ATGGCGCACCTACTCGGAGCCGAGGCCGTGCACCTGGCCTATCCGACTCAGGTGGTGTTCGAGGCAGTCACGCTCGGGGT
CAACGACGGGGCGCGCATCGGCATCGTCGGGCGAAACGGCGACGGCAAATCCAGTCTGCTGGGCCTGCTCACCGGTCAAC
TGCGGCCGGACTCCGGTCGGGTCACCCGGCGTAGCGGATTGCGGGTGAACGCGCTCAGCCAAACAGACACCCTCGACCCC
AACCGCACCGTCGGCTGGACGCTCATCGGTGACCAACCCGAACACCAATGGGCGGGCAACCCGCGTATCCGGGACGTGGT
CGCCGGCCTGGTATCCGACATCGCCTGGGACACCCCGGTCAGCACCCTCAGCGGTGGCCAGCGCCGACGGGTGCAACTGG
CCAGCCTGCTGGTCGGCGAATGGGACGTGATCGCTCTCGACGAGCCCACCAACCACCTCGACATCCAAGGCATCACCTGG
CTCGCCGACCACCTACGGCGGCGCTGGGCCCGCAATACCGGCGGCCTACTCGTGGTCACCCACGACCGCTGGTTCCTCGA
CGAGGTCGCCACCACAACATGGGAAGTGCACGACGGAATCGTCGAACCTTTCGAAGGCGGCTACGCGGCGTACGTGCTGC
AGCGCGTCGAGCGGGACCGGCTGACCGCCGCGGCCGAAGCCAAGCGGCAGAACCTGCTGCGCAAGGAGCTGGCTTGGTTG
CGCCGCGGCGCACCGGCGCGGACCTGCAAGCCCAAGTTCCGGATCGAGGCCGCCAACCAACTGATCGCAGACGTGCCGCC
ACCGCGCAACACCGTGGAGCTGGCCAAGCTGGCGGCCGCTCGGCTCGGAAAGGACGTCGTCGACCTGCTCGGCGTGTCGG
TCTCGTACCAGCCTTCTGGGGGCCGCCCGGTGTTGCGCGATATCGAATGGCGGATCGGCCCGGGTGAACGTATCGGCATC
GTCGGGGCTAACGGCGCCGGCAAGTCGACCCTGCTGGGCTTGATCGCCGGCACCGTCCAGCCCGGTGTCGGACGTGTCAA
GCCGTCCGGCTGGCAGTGCTCGATCAGCACGGGGACGATCTGGCACCGTTTGCCGACGACCGGATCGCCGATGTGCTAG

Upstream 100 bases:

>100_bases
GGCCCATCCCAGCCCGCATCGTCGCCACGCTAGAGCTCGACCGCGCGGCTCCTCAGCGGCCCATCCCAGCCCGCATCGTC
GCCACGCTAGGGTCGGCCCC

Downstream 100 bases:

>100_bases
GCAGGCTGCGTGGCGGCTATCAGGTCGAAGGCCGCGAGGTTACCCCGACCCAGCTGCTAGAGCGTCTCGGGTTCCGCCGG
GACCAGCTGTCCGCGCGAGT

Product: macrolide ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDP
NRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITW
LADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGI
VGANGAGKSTLLGLIAGTVQPGVGRVKPSGWQCSISTGTIWHRLPTTGSPMC

Sequences:

>Translated_372_residues
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDP
NRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITW
LADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGI
VGANGAGKSTLLGLIAGTVQPGVGRVKPSGWQCSISTGTIWHRLPTTGSPMC
>Mature_371_residues
AHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDPN
RTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWL
ADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWLR
RGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGIV
GANGAGKSTLLGLIAGTVQPGVGRVKPSGWQCSISTGTIWHRLPTTGSPMC

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=214, Percent_Identity=32.2429906542056, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI69354671, Length=240, Percent_Identity=30, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI10947135, Length=240, Percent_Identity=30, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI10947137, Length=368, Percent_Identity=24.7282608695652, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI27881506, Length=368, Percent_Identity=24.7282608695652, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI2367384, Length=372, Percent_Identity=31.989247311828, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789751, Length=364, Percent_Identity=28.021978021978, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787182, Length=379, Percent_Identity=29.023746701847, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787041, Length=386, Percent_Identity=24.8704663212435, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788165, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788897, Length=364, Percent_Identity=24.7252747252747, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787758, Length=175, Percent_Identity=30.8571428571429, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=227, Percent_Identity=33.4801762114537, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17553372, Length=378, Percent_Identity=28.3068783068783, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555318, Length=406, Percent_Identity=23.8916256157635, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321121, Length=385, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=349, Percent_Identity=27.7936962750716, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=343, Percent_Identity=25.6559766763848, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320874, Length=212, Percent_Identity=31.6037735849057, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24666836, Length=375, Percent_Identity=27.7333333333333, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24641342, Length=373, Percent_Identity=26.8096514745308, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 40340; Mature: 40208

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGR
CCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VTRRSGLRVNALSQTDTLDPNRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPV
EEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
STLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWLADHLRRRWARNTGGLLVVT
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEE
HDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
CCCHHHHHHHHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSG
HCCCCCCCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCEEEECCCC
GRPVLRDIEWRIGPGERIGIVGANGAGKSTLLGLIAGTVQPGVGRVKPSGWQCSISTGTI
CCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCE
WHRLPTTGSPMC
EEECCCCCCCCC
>Mature Secondary Structure 
AHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGR
CCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VTRRSGLRVNALSQTDTLDPNRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPV
EEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
STLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWLADHLRRRWARNTGGLLVVT
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEE
HDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
CCCHHHHHHHHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSG
HCCCCCCCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCEEEECCCC
GRPVLRDIEWRIGPGERIGIVGANGAGKSTLLGLIAGTVQPGVGRVKPSGWQCSISTGTI
CCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCE
WHRLPTTGSPMC
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]