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The map label for this gene is yfmR [H]

Identifier: 148661463

GI number: 148661463

Start: 1895095

End: 1895748

Strand: Reverse

Name: yfmR [H]

Synonym: MRA_1678

Alternate gene names: 148661463

Gene position: 1895748-1895095 (Counterclockwise)

Preceding gene: 148661464

Following gene: 148661462

Centisome position: 42.89

GC content: 66.21

Gene sequence:

>654_bases
GTGCTAGGCAGGCTGCGTGGCGGCTATCAGGTCGAAGGCCGCGAGGTTACCCCGACCCAGCTGCTAGAGCGTCTCGGGTT
CCGCCGGGACCAGCTGTCCGCGCGAGTCGACGACCTCTCCGGTGGTCAGCGTCGGCGGTTGCAGCTCATGCTGACGCTGT
TGTCCGAGCCGAACGTGCTGCTCCTCGACGAGCCCACCAACGACGTGGACACCGAGATGCTGACGGCGACCGAAGACCTG
CTTGACTCGTGGGCGGGTACGTTGATCGTCGTCTCACACGACCGGTATCTGCTCGAGCGGGTCACTGACCAGCAGTACGC
GATTCTCGATGACCGGTTGCGGCACCTGCCCGGCGGCATCGACGAATACCTGCAGCTGGCTGCCCGCGTTAGCGCCCCAG
CACCGGCCGAGCGGCCAGCGCCGCCGGCGATGTCGGGCGCACAGCGACGTGCCACCGAAAAAGAGTTGGCCGCAGTCGAC
CGTCAACTCGCCCGCCTGGCCGACCGGGTGGCCGCCAAACATACCGAACTGGCCGAGCATGACCAGTCCGACCACGTCGG
CATCACCCGGCTGACCCAGCAACTACGTGTCCTGCAAGACCACGTCGCGGCGATGGAGAATCGCTGGCTGGAGCTTTCGG
AGATGCTCGAATGA

Upstream 100 bases:

>100_bases
CCGTCCAGCCCGGTGTCGGACGTGTCAAGCCGTCCGGCTGGCAGTGCTCGATCAGCACGGGGACGATCTGGCACCGTTTG
CCGACGACCGGATCGCCGAT

Downstream 100 bases:

>100_bases
GGACGTATCGGACGGTGCGCTACCCGCTTGGCGAAGCGCTGCTGGCGCTGTATCGATGGCGCGGTCCGCTGATCAACGCC
GGAGTCGGTGGGCATGGCTA

Product: macrolide ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDL
LDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVD
RQLARLADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE

Sequences:

>Translated_217_residues
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDL
LDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVD
RQLARLADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
>Mature_217_residues
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDL
LDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVD
RQLARLADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947135, Length=104, Percent_Identity=31.7307692307692, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI69354671, Length=104, Percent_Identity=31.7307692307692, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI148612853, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1789751, Length=212, Percent_Identity=32.0754716981132, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367384, Length=166, Percent_Identity=33.1325301204819, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787041, Length=122, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787182, Length=86, Percent_Identity=40.6976744186046, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17553372, Length=102, Percent_Identity=39.2156862745098, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555318, Length=111, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=82, Percent_Identity=39.0243902439024, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641342, Length=89, Percent_Identity=39.3258426966292, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24666836, Length=88, Percent_Identity=38.6363636363636, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24642252, Length=111, Percent_Identity=30.6306306306306, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859989, Length=111, Percent_Identity=30.6306306306306, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 24472; Mature: 24472

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVL
CCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
LLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGI
EEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCH
DEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVL
CCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
LLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQYAILDDRLRHLPGGI
EEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCH
DEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]