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The map label for this gene is yebQ [C]

Identifier: 148661201

GI number: 148661201

Start: 1587520

End: 1589076

Strand: Reverse

Name: yebQ [C]

Synonym: MRA_1419

Alternate gene names: 148661201

Gene position: 1589076-1587520 (Counterclockwise)

Preceding gene: 148661202

Following gene: 148661196

Centisome position: 35.95

GC content: 65.57

Gene sequence:

>1557_bases
ATGCGAGCAGGACGTCGAGTCGCGATTAGCGCGGGCAGCCTGGCAGTACTGCTGGGCGCCCTGGACACCTATGTCGTGGT
CACCATCATGCGCGACATCATGAACAGCGTTGGTATACCGATCAACCAACTCCACCGGATCACCTGGATCGTCACGATGT
ACCTCCTGGGCTACATCGCCGCCATGCCGTTGCTGGGCCGGGCTTCCGACCGATTCGGGCGCAAGCTGATGCTGCAGGTC
AGCCTGGCCGGGTTCATCATCGGCTCGGTAGTGACCGCGCTGGCCGGGCATTTTGGCGATTTCCACATGCTGATCGCGGG
CCGCACGATCCAGGGTGTTGCCAGCGGCGCGCTATTGCCGATCACGCTGGCGCTGGGCGCCGATTTGTGGTCGCAGCGCA
ACCGCGCCGGCGTGCTCGGCGGTATCGGCGCCGCGCAGGAGCTCGGCAGCGTTCTGGGCCCGTTGTACGGAATCTTCATC
GTTTGGCTATTGCACGACTGGCGTGACGTGTTCTGGATCAACGTCCCGTTGACCGCGATCGCCATGGTAATGATCCACTT
CAGCCTGCCCTCACACGACCGCAGCACGGAGCCCGAGCGAGTCGACCTGGTCGGTGGTCTGCTGCTGGCACTCGCGTTGG
GCCTCGCCGTCATCGGGCTGTACAACCCCAATCCCGACGGCAAACACGTACTGCCGGACTACGGGGCTCCGTTGCTGGTC
GGCGCTCTCGTTGCCGCGGTGGCGTTCTTCGGTTGGGAACGTTTCGCTCGCACCCGGCTGATCGACCCGGCCGGTGTGCA
CTTCCGGCCGTTCCTGTCCGCGCTGGGTGCCTCCGTCGCCGCCGGCGCGGCGCTGATGGTGACGCTGGTTGATGTCGAGC
TGTTCGGCCAGGGCGTGCTGCAGATGGACCAGGCTCAGGCGGCCGGAATGCTGCTGTGGTTCCTTATCGCCCTACCGATC
GGGGCAGTGACGGGCGGGTGGATCGCCACCAGGGCCGGTGACCGTGCGGTGGCCTTTGCCGGACTGCTTATTGCGGCGTA
CGGTTACTGGCTTATTTCCCACTGGCCGGTGGACCTGTTGGCCGATCGGCACAACATCCTCGGATTGTTCACCGTGCCGG
CGATGCACACCGACCTGGTGGTGGCTGGTTTAGGGTTGGGGCTGGTGATCGGGCCGCTATCGTCGGCCACCCTACGGGTT
GTCCCGTCGGCCCAGCACGGCATCGCTTCGGCGGCGGTGGTGGTCGCCCGGATGACCGGCATGTTGATCGGCGTGGCCGC
GCTGAGCGCCTGGGGGTTGTACCGGTTCAACCAGATCCTGGCGGGGTTGTCGGCGGCCATCCCGCCCAACGCCAGCCTGC
TCGAGCGCGCGGCCGCAATTGGAGCCCGGTACCAGCAGGCGTTCGCGCTGATGTACGGCGAGATATTCACCATCACCGCG
ATCGTGTGCGTGTTCGGCGCGGTGCTAGGTCTGTTGATCAGCGGCCGCAAGGAACATGCCGATGAACCGGAAGTCCAGGA
GCAACCGACCCTGGCGCCCCAAGTGGAGCCGCTCTAA

Upstream 100 bases:

>100_bases
AGGCCCAGTTGGACCGCGGCTCGGGCAATTCCGTCCAGATGACCTTGTCGAAATGGGGCGAGAAGGTCCAGGTCACGAAG
CCCCCGGTGAGCTGATCAGC

Downstream 100 bases:

>100_bases
CGAGCCACCAAGCTCAGCAACAGATCCGGTCCGACCTTTTCGACGCTGTCGAACTGCCAACGCAACGCGTTGGTGATGTT
GGACACCCCGACGTCATCGA

Product: aminoglycosides/tetracycline-transport integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIAAMPLLGRASDRFGRKLMLQV
SLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLPITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFI
VWLLHDWRDVFWINVPLTAIAMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLV
GALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVLQMDQAQAAGMLLWFLIALPI
GAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLLADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRV
VPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITA
IVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL

Sequences:

>Translated_518_residues
MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIAAMPLLGRASDRFGRKLMLQV
SLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLPITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFI
VWLLHDWRDVFWINVPLTAIAMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLV
GALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVLQMDQAQAAGMLLWFLIALPI
GAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLLADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRV
VPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITA
IVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL
>Mature_518_residues
MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIAAMPLLGRASDRFGRKLMLQV
SLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLPITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFI
VWLLHDWRDVFWINVPLTAIAMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLV
GALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVLQMDQAQAAGMLLWFLIALPI
GAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLLADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRV
VPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITA
IVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL

Specific function: Confers resistance to tetracycline and aminoglycosides such as streptomycin and gentamicin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI87081983, Length=429, Percent_Identity=26.1072261072261, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790146, Length=151, Percent_Identity=31.7880794701987, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=327, Percent_Identity=26.9113149847095, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=187, Percent_Identity=26.7379679144385, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MFS55_MYCBO (Q7U042)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_855097.1
- ProteinModelPortal:   Q7U042
- EnsemblBacteria:   EBMYCT00000017226
- GeneID:   1092302
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1445c
- GeneTree:   EBGT00050000014781
- HOGENOM:   HBG564689
- OMA:   GWIATRV
- ProtClustDB:   CLSK791145
- BioCyc:   MBOV233413:MB1445C-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 54689; Mature: 54689

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e3e42b8)-; HASH(0x1dc65788)-; HASH(0x1b7c6c88)-; HASH(0x1d86d328)-; HASH(0x1e2e7860)-; HASH(0x1c6506c0)-; HASH(0x1aefe97c)-; HASH(0x1e1000b8)-; HASH(0x1dff43f0)-; HASH(0x1afe5630)-; HASH(0x1d2b6a8c)-; HASH(0x1e0ed1d8)-; HASH(0x1e3103f0)-; HASH(0x1e08f320)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AMPLLGRASDRFGRKLMLQVSLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLP
HHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCHHH
ITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLLHDWRDVFWINVPLTAI
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QMDQAQAAGMLLWFLIALPIGAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRVVPSAQHGIASAAVVVARMTG
HCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
MLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMNSVGIPINQLHRITWIVTMYLLGYIA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AMPLLGRASDRFGRKLMLQVSLAGFIIGSVVTALAGHFGDFHMLIAGRTIQGVASGALLP
HHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCHHH
ITLALGADLWSQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLLHDWRDVFWINVPLTAI
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AMVMIHFSLPSHDRSTEPERVDLVGGLLLALALGLAVIGLYNPNPDGKHVLPDYGAPLLV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GALVAAVAFFGWERFARTRLIDPAGVHFRPFLSALGASVAAGAALMVTLVDVELFGQGVL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QMDQAQAAGMLLWFLIALPIGAVTGGWIATRAGDRAVAFAGLLIAAYGYWLISHWPVDLL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ADRHNILGLFTVPAMHTDLVVAGLGLGLVIGPLSSATLRVVPSAQHGIASAAVVVARMTG
HCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
MLIGVAALSAWGLYRFNQILAGLSAAIPPNASLLERAAAIGARYQQAFALMYGEIFTITA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVCVFGAVLGLLISGRKEHADEPEVQEQPTLAPQVEPL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972