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The map label for this gene is PE_PGRS24

Identifier: 148661114

GI number: 148661114

Start: 1489464

End: 1491275

Strand: Reverse

Name: PE_PGRS24

Synonym: MRA_1333

Alternate gene names: 148661114

Gene position: 1491275-1489464 (Counterclockwise)

Preceding gene: 148661115

Following gene: 148661111

Centisome position: 33.74

GC content: 77.65

Gene sequence:

>1812_bases
ATGTCGTTTGTAATCGCCGCTCCCGAGACGCTGGTGAGGGCCGCTTCGGATTTGGCGAACATCGGGTCGACGCTGGGGGC
CGCCAACGCCGCGGCATTGGGCCCGACGACGGAACTTCTGGCAGCCGGTGCTGATGAGGTGTCGGCGGCCATCGCGTCGC
TGTTCGCCGCGCATGGCCAGGCCTATCAGGCGGTGAGCGCTCAGATGTCGGCGTTTCATGCCCAGTTCGTTCAAACCTTT
ACTGCGGGCGCTGGCGCGTACGCGAGCGCTGAGGCCGCCGCCGCGGCGCCGTTGGAGGGCCTGCTCAACATTGTGAACAC
GCCCACCCAGCTGTTGCTGGGGCGTCCGCTGATCGGCAACGGCGCCAACGGCGCACCGGGGACCGGGCAAGCCGGCGGGG
CCGGCGGGCTGCTGTACGGCAACGGCGGGGCCGGCGGGTCCGGGGCGCCCGGCCAGGCCGGCGGCCCAGGTGGAGCCGCG
GGGCTATTCGGCAACGGCGGGGCGGGTGGGGCCGGGGGTGACGGCCCGGGCAACGGCGCGGCTGGCGGGGCCGGCGGGGC
CGGCGGGCTGCTGTTCGGCTCCGGCGGCGCCGGTGGGCCCGGCGGAGTCGGGAACACCGGCACAGGCGGGCTCGGCGGCG
ACGGCGGGGCGGCCGGGCTGTTCGGAGCCGGTGGCATCGGCGGGGCCGGCGGGCCAGGCTTCAACGGTGGCGCCGGCGGG
GCCGGCGGTCGCAGCGGGCTGTTCGAGGTGTTGGCCGCCGGCGGTGCCGGCGGCACCGGCGGGTTGAGCGTCAACGGGGG
CACCGGTGGCACCGGCGGCACCGGCGGGGGCGGCGGGCTGTTCTCCAATGGCGGTGCCGGCGGCGCCGGCGGGTTCGGAG
TCTCCGGCTCGGCCGGAGGGAACGGCGGCACCGGAGGCGACGGCGGCATCTTCACCGGCAACGGCGGGACCGGCGGCACC
GGCGGAACTGGCACCGGTAACCAACTCGTGGGCGGTGAGGGCGGGGCCGGCGGGGCGGGCGGCAACGCCGGCATCCTCTT
CGGCGCTGGCGGCATTGGCGGCACCGGCGGAACCGGTCTCGGCGCGCCCGACCCCGGCGGCACCGGCGGCAAAGGAGGCG
TCGGCGGCATCGGCGGTGCCGGCGCACTGTTCGGTCCCGGCGGCGCCGGGGGCACCGGAGGGTTCGGCGCCTCCAGTGCG
GACCAAATGGCCGGCGGCATCGGCGGGTCCGGTGGCAGCGGCGGGGCCGCCAAGCTGATCGGCGACGGCGGCGCCGGCGG
TACCGGCGGCGACAGCGTCCGGGGCGCGGCCGGTAGCGGCGGCACCGGCGGCACCGGCGGGTTGATCGGTGACGGCGGCG
CTGGTGGCGCCGGCGGGACTGGCATCGAATTCGGGTCGGTCGGGGGGGCCGGCGGGGCCGGCGGCAACGCCGCCGGGCTC
TCGGGTGCGGGCGGGGCCGGCGGAGCCGGCGGGTTCGGCGAGACCGCCGGCGACGGTGGGGCCGGCGGCAACGCCGGCCT
GCTCAACGGCGATGGCGGCGCCGGCGGCGCCGGCGGACTCGGCATCGCCGGCGACGGGGGGAACGGCGGCAAGGGTGGCA
AGGCCGGGATGGTCGGCAACGGCGGCGACGGCGGCGCCGGCGGCGCAAGCGTGGTGGCAAACGGCGGTGTCGGCGGCTCC
GGCGGCAACGCCACCCTGATCGGCAATGGAGGCAACGGCGGAAACGGCGGAGTCGGCAGTGCGCCGGGTAAGGGTGGCGC
CGGCGGCACCGCCGGGCTGCTCGGCCTGAACGGATCACCCGGGTTGTCGTAG

Upstream 100 bases:

>100_bases
TGCACACTGCACTCCGAGATTGATCAGAAAGGCTAAGCGATAGCGCTACCCTGTGCTAACTCGAGCTGGATACTCGACGC
ACAGCTGATCGGAGGAAAGC

Downstream 100 bases:

>100_bases
CCGCCCAGCGCGAGCAGACGCAGAATCGCCTAAACCCGTGCGGGTTTAGGCGATTCTGCGTCTGCTCGCCAGCCGGCCTC
AGTACAGCGCGTTGGCGAGG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTF
TAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGGPGGAA
GLFGNGGAGGAGGDGPGNGAAGGAGGAGGLLFGSGGAGGPGGVGNTGTGGLGGDGGAAGLFGAGGIGGAGGPGFNGGAGG
AGGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGLFSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGT
GGTGTGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGLGAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSA
DQMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGL
SGAGGAGGAGGFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGNGGDGGAGGASVVANGGVGGS
GGNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSPGLS

Sequences:

>Translated_603_residues
MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTF
TAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGGPGGAA
GLFGNGGAGGAGGDGPGNGAAGGAGGAGGLLFGSGGAGGPGGVGNTGTGGLGGDGGAAGLFGAGGIGGAGGPGFNGGAGG
AGGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGLFSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGT
GGTGTGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGLGAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSA
DQMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGL
SGAGGAGGAGGFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGNGGDGGAGGASVVANGGVGGS
GGNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSPGLS
>Mature_602_residues
SFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQMSAFHAQFVQTFT
AGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGGPGGAAG
LFGNGGAGGAGGDGPGNGAAGGAGGAGGLLFGSGGAGGPGGVGNTGTGGLGGDGGAAGLFGAGGIGGAGGPGFNGGAGGA
GGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGLFSNGGAGGAGGFGVSGSAGGNGGTGGDGGIFTGNGGTGGTG
GTGTGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGLGAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSAD
QMAGGIGGSGGSGGAAKLIGDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGLS
GAGGAGGAGGFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGNGGDGGAGGASVVANGGVGGSG
GNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSPGLS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PG24_MYCTU (Q10637)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   A70770
- RefSeq:   NP_335816.1
- RefSeq:   YP_177799.1
- ProteinModelPortal:   Q10637
- EnsemblBacteria:   EBMYCT00000001643
- EnsemblBacteria:   EBMYCT00000071741
- GeneID:   886899
- GeneID:   924716
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1367
- KEGG:   mtu:Rv1325c
- TIGR:   MT1367
- TubercuList:   Rv1325c
- GeneTree:   EBGT00070000031790
- HOGENOM:   HBG131154
- OMA:   DIAGLEW
- ProtClustDB:   CLSK799793
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 49576; Mature: 49444

Theoretical pI: Translated: 3.96; Mature: 3.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQ
CCEEEECHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHCCH
AYQAVSAQMSAFHAQFVQTFTAGAGAYASAEAAAAAPLEGLLNIVNTPTQLLLGRPLIGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
GANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGGPGGAAGLFGNGGAGGAGGDGPGNGA
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGAGGAGGLLFGSGGAGGPGGVGNTGTGGLGGDGGAAGLFGAGGIGGAGGPGFNGGAGG
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGRSGLFEVLAAGGAGGTGGLSVNGGTGGTGGTGGGGGLFSNGGAGGAGGFGVSGSAGG
CCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGGTGGDGGIFTGNGGTGGTGGTGTGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGL
CCCCCCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCC
GAPDPGGTGGKGGVGGIGGAGALFGPGGAGGTGGFGASSADQMAGGIGGSGGSGGAAKLI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEE
GDGGAGGTGGDSVRGAAGSGGTGGTGGLIGDGGAGGAGGTGIEFGSVGGAGGAGGNAAGL
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
SGAGGAGGAGGFGETAGDGGAGGNAGLLNGDGGAGGAGGLGIAGDGGNGGKGGKAGMVGN
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
GGDGGAGGASVVANGGVGGSGGNATLIGNGGNGGNGGVGSAPGKGGAGGTAGLLGLNGSP
CCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
GLS
CCC
>Mature Secondary Structure 
SFVIAAPETLVRAASDLANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFAAHGQ
CEEEECHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHCCH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CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036