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The map label for this gene is cyp130

Identifier: 148661043

GI number: 148661043

Start: 1404696

End: 1405913

Strand: Reverse

Name: cyp130

Synonym: MRA_1264

Alternate gene names: 148661043

Gene position: 1405913-1404696 (Counterclockwise)

Preceding gene: 148661044

Following gene: 148661042

Centisome position: 31.81

GC content: 67.24

Gene sequence:

>1218_bases
ATGACATCAGTAATGTCTCACGAATTCCAGCTCGCCACCGCCGAAACCTGGCCGAATCCGTGGCCGATGTACCGCGCGTT
GCGCGACCACGACCCGGTGCACCACGTCGTCCCGCCGCAGCGTCCCGAGTACGACTACTACGTGCTGTCCCGGCACGCCG
ACGTCTGGTCGGCAGCGCGGGACCATCAGACGTTCTCGTCGGCGCAAGGCTTGACCGTTAACTACGGCGAGCTGGAAATG
ATTGGACTGCACGACACCCCGCCCATGGTGATGCAGGATCCGCCGGTCCACACCGAGTTTCGCAAGCTGGTGTCGCGCGG
CTTCACGCCACGACAGGTCGAAACCGTCGAGCCCACGGTGCGCAAGTTCGTCGTTGAGCGGCTCGAAAAGCTGCGCGCCA
ACGGTGGCGGCGACATTGTCACCGAACTATTCAAACCGCTCCCGTCGATGGTGGTGGCGCACTATCTCGGTGTTCCCGAA
GAGGATTGGACGCAATTCGACGGGTGGACCCAGGCCATCGTGGCGGCGAACGCGGTTGACGGCGCCACCACCGGCGCACT
GGACGCGGTCGGCTCGATGATGGCCTACTTCACCGGGCTGATCGAGCGACGCCGCACCGAGCCCGCCGACGACGCCATCT
CCCACCTGGTAGCCGCCGGGGTCGGCGCCGACGGCGACACCGCCGGCACACTGTCCATACTGGCGTTCACGTTCACCATG
GTCACCGGCGGCAACGACACCGTCACCGGCATGCTAGGCGGTTCGATGCCGTTGCTGCACCGGCGGCCCGACCAGCGCCG
GCTGCTGCTGGATGACCCAGAGGGCATCCCCGACGCGGTCGAGGAGCTGCTGCGGCTCACCTCGCCGGTGCAGGGGCTGG
CGCGCACAACCACGCGCGACGTCACGATCGGTGACACCACCATCCCGGCCGGTCGCCGGGTGCTGCTGCTGTACGGCTCG
GCCAACCGTGACGAACGCCAATACGGCCCGGACGCAGCCGAACTCGATGTCACTCGGTGCCCGCGCAACATCTTGACCTT
CAGCCACGGCGCCCACCACTGCCTGGGTGCGGCCGCGGCCCGGATGCAATGCCGGGTGGCGCTGACCGAACTGCTGGCCC
GGTGCCCGGACTTCGAGGTGGCCGAGTCACGCATCGTGTGGTCCGGCGGCAGTTATGTCCGGCGTCCGCTGTCGGTGCCG
TTCCGAGTGACATCCTGA

Upstream 100 bases:

>100_bases
CCCGCCGAGTGTGAACCGCACGACGCGTCCTCGGCGTGTCGCGTCACCAGATTCACAATCGCCGATTGATATTACCGATG
GAATGTCTTAGACATAAGAC

Downstream 100 bases:

>100_bases
TGGCGGGTACCGACTGGCTGTCCGCGCGTCGGACCGAGTTAGCCGCAGATCGGATACTCGACGCCGCCGAGCGACTCTTT
ACGCAGCGTGACCCGGCGTC

Product: putative cytochrome p450 130 CYP130

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEM
IGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPE
EDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGS
ANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVP
FRVTS

Sequences:

>Translated_405_residues
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEM
IGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPE
EDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGS
ANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVP
FRVTS
>Mature_404_residues
TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEMI
GLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEE
DWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMV
TGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSA
NRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPF
RVTS

Specific function: Unknown

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CP130_MYCTU (Q11062)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   H70752
- RefSeq:   NP_215772.1
- RefSeq:   NP_335739.1
- PDB:   2UUQ
- PDB:   2UVN
- PDB:   2WGY
- PDB:   2WH8
- PDB:   2WHF
- PDBsum:   2UUQ
- PDBsum:   2UVN
- PDBsum:   2WGY
- PDBsum:   2WH8
- PDBsum:   2WHF
- ProteinModelPortal:   Q11062
- SMR:   Q11062
- EnsemblBacteria:   EBMYCT00000003958
- EnsemblBacteria:   EBMYCT00000069210
- GeneID:   887059
- GeneID:   924775
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1295
- KEGG:   mtu:Rv1256c
- TIGR:   MT1295
- TubercuList:   Rv1256c
- GeneTree:   EBGT00050000015569
- HOGENOM:   HBG695262
- OMA:   AELFKPL
- ProtClustDB:   CLSK791054
- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972
- Gene3D:   G3DSA:1.10.630.10
- PRINTS:   PR00359

Pfam domain/function: PF00067 p450; SSF48264 Cytochrome_P450

EC number: NA

Molecular weight: Translated: 44581; Mature: 44450

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR
CCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV
HHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCHHH
RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCC
GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD
EECCCCEEEEECCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA
EEECCCCCCCCCEEEEEECCCCCCHHHCCCCHHHCCHHHCCHHHHHCCCCHHHHHHHHHH
RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
HHHHHHHHHHHHHHCCCCHHCCCEEEECCCHHHHCCCCCCEEECC
>Mature Secondary Structure 
TSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV
HHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCHHH
RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCC
GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD
EECCCCEEEEECCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA
EEECCCCCCCCCEEEEEECCCCCCHHHCCCCHHHCCHHHCCHHHHHCCCCHHHHHHHHHH
RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
HHHHHHHHHHHHHHCCCCHHCCCEEEECCCHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036