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The map label for this gene is pabB [H]

Identifier: 148660787

GI number: 148660787

Start: 1123530

End: 1124906

Strand: Reverse

Name: pabB [H]

Synonym: MRA_1014

Alternate gene names: 148660787

Gene position: 1124906-1123530 (Counterclockwise)

Preceding gene: 148660789

Following gene: 148660786

Centisome position: 25.45

GC content: 68.99

Gene sequence:

>1377_bases
TTGAACTTAGCGTGGGAGCTTAGCACGCGGACGAAATCCCCACGCAGCCACTTGCGCTGCGAAAATCCACAGTTCTGTCA
AGCTAGAACGGTGCGAATCGACCGACTCGGCGATCTTGGCGGAGCGCCTGCGGTGCTGCGGGCGGTCGGCCGCGCCACCA
GTCGACTCGACTTGCCACCACCGGCGGCGCTGACCGGCGAATGGTTCGGTGCGCTGGCGGTGATCGCACCGAGTGTGTCT
ATACAACCGGTCAGCGGCGACGACGTGTTCTCGGGCCCGCCGGGCACCGGCGGGCCCGATGCCACCGGGGCGGTGGGCGG
CGGCTGGGTCGGCTACCTGTCCTACCCGGACGCCGGCGCCGACGGGCGACCCCACCGGATCCCCGAGGCCGCCGGCGGCT
GGACCGATTGCGTGCTGCGCCGCGACCGCGACGGCCAGTGGTGGTATGAGAGCCTGTCCGGTGCGCCGATAGCGGACTGG
CTGGCCAGCGCGTTGGCGACCACTCGGGCATCGGTCGCCAGACCGGCACCGGCATGCCGGATCGACTGGGAACCGGCCGA
CCGGGCAGCGCACCGCGACGGGGTACTGGCGTGTCTGGAAGCTATCGGCGCGGGCGAGGTCTATCAAGCGTGCGTGTGCA
CCCAATTCGCCGGGACGGTCACCGGATCCCCGCTGGACTTCTTCATCGACGGGTTCGGTCGTACCGCTCCGTCCCGGTCC
GCCTTTGTCGCCGGACCGTGGGGAGCCGTCGCATCGCTATCCCCGGAGCTATTCCTGCGCCGCCGCGGGTCCGTGGTGAC
ATCGAGCCCGATCAAGGGCACGCTGCCGCTGGACGCCCCGCCGTCGGCGCTGCGGGCATCGGCCAAAGAGGTGGCCGAGA
ACATCATGATCGTGGATCTGGTCCGCAACGACCTCGGCCGGGTAGCGGTTACCGGTACCGTGACGGTGCCCGAGCTGTTG
GTGGTGCGACCAGCGCCGGGAGTGTGGCACCTGGTGTCCACGGTGTCGGCGCGGGTTCCGCTCGAGGAACCGATGTCAGC
GCTGCTCGACGCCGCCTTCCCGCCGGCCTCGGTCACCGGCACACCTAAACTGCGGGCTCGCCAATTGATTTCACAATGGG
AGCGATATCGCCGCGGGATATATTGCGGCACAGTCGGTTTGGCGTCACCGGTCGCCGGATGCGAGCTCAACGTCGCAATC
CGCACCGTCGAATTCGATACCGCAGGCAACGCCGTGCTGGGCGTTGGCGGCGGGATCACCGCCGACTCCGATCCGGACGC
CGAATGGGCGGAGTGCCTGCACAAAGCCGCTCCCATCGTCGGGCTGCCGGCCGCCACGCGCACCACCCCGGCTCGGTTAG
CCAGCAAAGTGCGGTAG

Upstream 100 bases:

>100_bases
ACACCGAGCGTCAACGTCTCGCGGTCAGCGAGAATCGGCATTGGCATTGGCTGCTCGCACAGCAACACCCCCCGGGACGG
AGACCGGAGCCGGTCACGGA

Downstream 100 bases:

>100_bases
CCCAGCGGGCGGCGGAAATTGGCATAACGCCCACATGGTGTGCCGGGTGCGCCTAAGCTCGGGCCATCGACGCGTGTCTA
TCTCGTGTCGAGTTCGAGAG

Product: aminodeoxychorismate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAPSVS
IQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADW
LASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPELL
VVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAI
RTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR

Sequences:

>Translated_458_residues
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAPSVS
IQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADW
LASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPELL
VVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAI
RTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
>Mature_458_residues
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAPSVS
IQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGADGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADW
LASALATTRASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPELL
VVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAI
RTVEFDTAGNAVLGVGGGITADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=267, Percent_Identity=40.0749063670412, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1787518, Length=266, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082077, Length=197, Percent_Identity=30.9644670050761, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=226, Percent_Identity=35.3982300884956, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=28.6713286713287, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 47899; Mature: 47899

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPP
CCCEEECCCCCCCCHHHCCCCCCCCCCHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGA
CCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
DGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADWLASALATTRASVARPAPACR
CCCCCCCCCCCCCHHHHHEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
IDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
ECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCC
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDL
EEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEE
VRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTG
HHHCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
TPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGIT
CCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCEEEEEEEEEEECCCCCEEEECCCCCC
ADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
CCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPP
CCCEEECCCCCCCCHHHCCCCCCCCCCHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGA
CCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
DGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADWLASALATTRASVARPAPACR
CCCCCCCCCCCCCHHHHHEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
IDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
ECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCC
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDL
EEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEE
VRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTG
HHHCCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
TPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGIT
CCHHHHHHHHHHHHHHHCCEEEECCHHCCCCCCCEEEEEEEEEEECCCCCEEEECCCCCC
ADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR
CCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]