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The map label for this gene is yjfR [C]

Identifier: 148660684

GI number: 148660684

Start: 1010251

End: 1011369

Strand: Direct

Name: yjfR [C]

Synonym: MRA_0913

Alternate gene names: 148660684

Gene position: 1010251-1011369 (Clockwise)

Preceding gene: 148660683

Following gene: 148660685

Centisome position: 22.86

GC content: 68.45

Gene sequence:

>1119_bases
ATGGTGCGCCGAGCGCTACGACTGGCGGCCGGCACCGCCTCGCTGGCCGCCGGCACGTGGCTGTTGCGTGCGCTGCACGG
CACGCCGGCCGCGCTCGGTGCCGACGCGGCGTCGATCAGGGCTGTGTCGGAGCAATCGCCGAACTATCGTGACGGCGCCT
TCGTCAACCTGGATCCCGCGTCGATGTTCACCCTGGATCGCGAGGAGCTTCGGCTCATCGTGTGGGAGTTAGTGGCCAGA
CACAGTGCGAGCCGGCCGGCGGCGCCGATCCCGTTGGCCTCGCCGAATATCTACCGGGGTGACGCCAGCCGGCTCGCCGT
CAGCTGGTTCGGTCACTCGACGGCGCTGCTGGAAATCGACGGCTACCGGGTGCTTACCGATCCGGTGTGGAGCGATCGGT
GCTCACCGTCCGACGTCGTCGGCCCCCAGCGCCTGCATCCGCCGCCGGTGCAACTGGCAGCTCTCCCGGCCGTCGACGCC
GTGGTCATCAGCCACGACCACTACGACCATCTCGATATCGACACCGTGGTTGCGCTGGTCGGCATGCAACGGGCCCCGTT
CCTTGTGCCGCTCGGGGTCGGCGCCCACCTTCGGTCGTGGGGTGTTCCGCAGGATCGCATTGTTGAGCTCGACTGGAACC
AGAGCGCTCAGGTCGATGAGCTCACCGTGGTCTGCGTGCCGGCACGGCACTTCTCGGGACGGTTCCTGAGCCGCAACACC
ACACTGTGGGCCTCGTGGGCGTTTGTTGGGCCGAACCATCGCGCCTACTTCGGCGGTGATACCGGATACACCAAGAGCTT
CACCCAGATCGGCGCGGACCACGGACCGTTCGACCTGACCCTGCTGCCCATCGGGGCCTACAACACGGCGTGGCCGGACA
TCCACATGAACCCCGAGGAGGCGGTCCGGGCGCACCTGGACGTCACCGATTCGGGCTCGGGAATGCTGGTGCCGGTGCAC
TGGGGCACCTTCCGGCTGGCCCCCCATCCGTGGGGCGAGCCGGTCGAGCGGCTGCTCGCGGCGGCTGAACCCGAGCACGT
CACGGTAGCCGTGCCGCTACCCGGTCAGCGGGTCGACCCGACCGGGCCCATGAGATTGCACCCATGGTGGCGGCTGTAA

Upstream 100 bases:

>100_bases
AGGAACTCTTCGACAAAGCCTGGGGCAGCCAGGATGTCATCGAAGCGCAGGTTGCCCGGATGGAAAAGCGGCCGCCGAAG
TTCCAAGGGGCTTAACCGTC

Downstream 100 bases:

>100_bases
TTCCCCGCAGCGCCCGGCTAATGGTGCTAGGGGGCGAGCCGAGGCGATCAAACCACCGAGTGTTCCGGCCGCGTTGGCTA
CTATCTGCGGCCATGACCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVAR
HSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDA
VVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT
TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVH
WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL

Sequences:

>Translated_372_residues
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVAR
HSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDA
VVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT
TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVH
WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL
>Mature_372_residues
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVAR
HSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDA
VVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT
TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVH
WGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA

Homologues:

Organism=Homo sapiens, GI170932483, Length=247, Percent_Identity=42.5101214574899, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI170932481, Length=247, Percent_Identity=42.5101214574899, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17543104, Length=249, Percent_Identity=40.1606425702811, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17543102, Length=273, Percent_Identity=36.2637362637363, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17543100, Length=273, Percent_Identity=36.2637362637363, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25148824, Length=250, Percent_Identity=38.4, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6325154, Length=255, Percent_Identity=32.9411764705882, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y906_MYCTU (P64759)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   G70783
- RefSeq:   NP_215421.1
- RefSeq:   NP_335362.1
- ProteinModelPortal:   P64759
- EnsemblBacteria:   EBMYCT00000002956
- EnsemblBacteria:   EBMYCT00000070182
- GeneID:   885150
- GeneID:   926244
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0929
- KEGG:   mtu:Rv0906
- TIGR:   MT0929
- TubercuList:   Rv0906
- GeneTree:   EBGT00050000017642
- HOGENOM:   HBG741314
- OMA:   HWATFNL
- ProtClustDB:   CLSK871871

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40642; Mature: 40642

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCHHHEEEHHCCCCCCCCCEEEEECCH
SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID
HEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCEEEEEEC
GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHH
GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT
CCCCCCEEEEECCCCHHHHCCCCHHHEEEECCCCCCCCCEEEEEEEECCCCCCEEEECCC
TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE
EEEEEEEEECCCCEEEECCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHH
AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP
HHEEEEEEECCCCEEEEEEECCEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
TGPMRLHPWWRL
CCCEEECCCCCC
>Mature Secondary Structure
MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPA
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCHHHEEEHHCCCCCCCCCEEEEECCH
SMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEID
HEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCEEEEEEC
GYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALV
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHH
GMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNT
CCCCCCEEEEECCCCHHHHCCCCHHHEEEECCCCCCCCCEEEEEEEECCCCCCEEEECCC
TLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEE
EEEEEEEEECCCCEEEECCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHH
AVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDP
HHEEEEEEECCCCEEEEEEECCEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
TGPMRLHPWWRL
CCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036