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The map label for this gene is msrR [H]

Identifier: 148660600

GI number: 148660600

Start: 915563

End: 917617

Strand: Reverse

Name: msrR [H]

Synonym: MRA_0832

Alternate gene names: 148660600

Gene position: 917617-915563 (Counterclockwise)

Preceding gene: 148660601

Following gene: 148660599

Centisome position: 20.76

GC content: 65.3

Gene sequence:

>2055_bases
ATGAGTGACGGCGAGAGCGCCGCGCCGTGGGCACGGCTCTCCGAGTCAGCATTCCCCGATGGTGTTGACCGATGGATCAC
GGTACCGCCCGCCACATGGGTGGCAGCCCAGGGTCCGCGGGACACCCAGAATGTCGGCTGTCATGCCACCGGCGCCGTTA
GTGTGGCCGATCTGATCGCCAGGCTCGGCCCCGCTTTTCCTGACCTCCCCACGCACCGCCATGTCGCCCCCGAACCCGAG
CCATCCGGCCGCGGCCCGAAGGTCCACGACGACGCCGACGACCAGCAGGACACCGAGGCTATCGCCATCCCGGCCCACTC
GCTCGAGTTCCTCTCGGAGCTTCCCGACCTCCGGGCAGCCAACTATCCGCGCGCCGACCACGCCCGCCGTGAACCCGAGC
TACCCGGCAAGCAGCTAACCGGATCGGCTCGAGTGCGGCCATTGCGGATCCGCCGAACGTCGCCCGCGCCCGCCAAGCCA
GCGCCGAACTCCGGCCGGCGCCCGATGGTGCTGGCCGCGCGCTCGCTGGCGGCTCTGTTTGCCGCTCTGGCGTTGGCGCT
GACCGGCGGGGCATGGCAGTGGAGCGCGTCGAAGAACAGCCGGCTGAACATGGTAAGCGCGCTCGACCCGCATTCGGGCG
ACATCGTCAACCCCAGCGGGCAGCATGGCGACGAGAACTTCTTGCTCGTCGGTATGGACTCTCGTGCCGGGGCGAACGCC
AATATCGGCGCCGGCGACGCCGAGGACGCCGGCGGCGCACGTTCGGACACCGTCATGCTGGTCAACATTCCGGCCAGCCG
CGAGCGGGTCGTCGCGGTGTCGTTCCCCCGCGACCTGGCGATCACTCCAATCCAATGCGAGGCGTGGAACCCCGAGACCG
GTAAGTACGGACCCATCTACGACGAGAAGACGGGAACGATGGGTCCCAGACTGGTGTACACGGAGACCAAGCTGAACTCG
GCATTCTCCTTCGGCGGGCCTAAGTGTCTAGTGAAGGTCATTCAGAAACTGTCGGGCTTGAGCATCAACCGGTTCATCGC
GATTGACTTCGTCGGTTTCGCGCGGATGGTCGAGGCCCTCGGCGGCGTCGAGGTATGCAGCACCACCCCGTTGCGGGACT
ACGAACTGGGCACGGTGCTGGAGCACGCCGGACGCCAGGTCATTGACGGGCCGACCGCGCTGAACTATGTGCGCGCTCGC
CAGGTCACCACCGAGAGCAATGGCGACTACGGGCGCATCAAACGCCAGCAGTTGTTTTTGTCGTCGCTGCTGCGTTCGAT
GATCTCGACGGACACCTTGTTCAACCTCAGCAGGCTCAACAACGTCGTCAACATGTTCATCGGTAACAGCTACGTGGACA
ACGTCAAGACCAAAGACCTGGTCGAACTCGGTCGATCGTTGCAGCATATGGCGGCCGGGCACGTCACGTTCGTGACCGTT
CCGACCGGTATAACCGACCAGAACGGCGACGAGCCCCCGCGTACCTCCGACATGAAGGCGCTTTTCACCGCCATCATCGA
CGACGATCCGCTGCCCCTGGAAAACGATCACAACGCCCAGCGTCTGGGCAACACGCCGTCGACCCCGCCGACCACCACCA
AGAAGGCGCCGCAGGCGGGTCTGACCAACGAGATTCAGCACCAGCAGGTTACGACGACCTCGCCAAAAGAGGTCACAGTG
CAGGTCTCTAACTCGACCGGCCAGGCCGGTTTGGCCACCACCGCCACCGATCAGCTCAAGCGGAACGGCTTCAACGTGAT
GGCTCCGGACGACTACCCGAGTTCGCTGCTGGCCACCACAGTGTTTTTTTCGCCCGGCAACGAACAGGCTGCCGCCACCG
TGGCCGCCGTGTTCGGCCAGTCAAAGATCGAGCGGGTGACCGGGATCGGCCAACTGGTCCAGGTGGTGCTGGGCCAAGAC
TTCAGCGCGGTGCGCGCTCCCCTGCCGAGTGGCTCCACCGTCAGCGTGCAGATAAGCCGCAACTCCTCCAGCCCACCGAC
CAAGCTGCCCGAGGACCTGACGGTCACCAACGCCGCCGACACCACCTGCGAGTAG

Upstream 100 bases:

>100_bases
TGCGGCGCCGACTCGTGGCGGTGCTGCGCGAAGGTGCGCGTAGGACACGCAGCCAACACCGCGGGCGTCCGCCACCTAGA
CTCTCGGAGGCCGGTAGGAC

Downstream 100 bases:

>100_bases
CCGCATTGACACGACGCTTACGGCATTTTCCAAGGTCGGGAACGTAGGCTTTAGCACATGCGGACCGCCTACCATGAGCA
ACTCTCGGAATTATCCGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MSDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIARLGPAFPDLPTHRHVAPEPE
PSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAANYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKP
APNSGRRPMVLAARSLAALFAALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANA
NIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIYDEKTGTMGPRLVYTETKLNS
AFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEALGGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRAR
QVTTESNGDYGRIKRQQLFLSSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTV
PTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAGLTNEIQHQQVTTTSPKEVTV
QVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATTVFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQD
FSAVRAPLPSGSTVSVQISRNSSSPPTKLPEDLTVTNAADTTCE

Sequences:

>Translated_684_residues
MSDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIARLGPAFPDLPTHRHVAPEPE
PSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAANYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKP
APNSGRRPMVLAARSLAALFAALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANA
NIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIYDEKTGTMGPRLVYTETKLNS
AFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEALGGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRAR
QVTTESNGDYGRIKRQQLFLSSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTV
PTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAGLTNEIQHQQVTTTSPKEVTV
QVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATTVFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQD
FSAVRAPLPSGSTVSVQISRNSSSPPTKLPEDLTVTNAADTTCE
>Mature_683_residues
SDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIARLGPAFPDLPTHRHVAPEPEP
SGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAANYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKPA
PNSGRRPMVLAARSLAALFAALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANAN
IGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIYDEKTGTMGPRLVYTETKLNSA
FSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEALGGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRARQ
VTTESNGDYGRIKRQQLFLSSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTVP
TGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAGLTNEIQHQQVTTTSPKEVTVQ
VSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATTVFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQDF
SAVRAPLPSGSTVSVQISRNSSSPPTKLPEDLTVTNAADTTCE

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 72906; Mature: 72774

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIA
CCCCCCCCCHHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHH
RLGPAFPDLPTHRHVAPEPEPSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCCC
NYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKPAPNSGRRPMVLAARSLAALF
CCCCCHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
AALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANA
HHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
NIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIY
CCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCC
DEKTGTMGPRLVYTETKLNSAFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEAL
CCCCCCCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
GGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRARQVTTESNGDYGRIKRQQLFL
CCCEEECCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHH
SSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEE
PTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
LTNEIQHQQVTTTSPKEVTVQVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATT
CCHHHHHCEECCCCCCEEEEEEECCCCCCCCEEHHHHHHHHCCCEEECCCCCCHHHEEEE
VFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQDFSAVRAPLPSGSTVSVQISR
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEEC
NSSSPPTKLPEDLTVTNAADTTCE
CCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIA
CCCCCCCCHHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHH
RLGPAFPDLPTHRHVAPEPEPSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCCC
NYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKPAPNSGRRPMVLAARSLAALF
CCCCCHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
AALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANA
HHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
NIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIY
CCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCC
DEKTGTMGPRLVYTETKLNSAFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEAL
CCCCCCCCCEEEEEECCCCCHHCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
GGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRARQVTTESNGDYGRIKRQQLFL
CCCEEECCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHH
SSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEE
PTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAG
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
LTNEIQHQQVTTTSPKEVTVQVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATT
CCHHHHHCEECCCCCCEEEEEEECCCCCCCCEEHHHHHHHHCCCEEECCCCCCHHHEEEE
VFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQDFSAVRAPLPSGSTVSVQISR
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEEC
NSSSPPTKLPEDLTVTNAADTTCE
CCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]