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The map label for this gene is eccE3

Identifier: 148660058

GI number: 148660058

Start: 357242

End: 358237

Strand: Direct

Name: eccE3

Synonym: MRA_0301

Alternate gene names: 148660058

Gene position: 357242-358237 (Clockwise)

Preceding gene: 148660057

Following gene: 148660060

Centisome position: 8.08

GC content: 68.67

Gene sequence:

>996_bases
ATGAACCCGATCCCTTCTTGGCCCGGCAGGGGCCGGGTCACGTTGGTGCTGCTGGCGGTGGTGCCTGTAGCGCTGGCCTA
CCCCTGGCAATCGACACGCGATTACGTGCTGCTGGGCGTGGCCGCCGCCGTCGTGATTGGGCTATTCGGCTTCTGGCGCG
GGCTGTATTTCACCACGATCGCGCGCCGCGGGTTGGCAATCCTGCGCCGCCGACGCCGGATTGCCGAGCCCGCAACGTGC
ACGCGCACAACGGTGCTGGTGTGGGTTGGGCCGCCGGCATCGGATACGAACGTGCTGCCGCTGACGCTGATCGCCCGGTA
TTTGGACCGATACGGCATCCGCGCCGACACGATTCGCATCACCAGCCGCGTCACCGCATCCGGCGACTGCCGGACCTGGG
TCGGGTTGACGGTGGTCGCCGACGATAACCTGGCGGCGCTGCAGGCCCGGTCAGCGCGCATCCCCTTGCAAGAGACCGCG
CAGGTCGCGGCGCGCCGGCTCGCCGACCATCTGCGCGAAATCGGTTGGGAGGCTGGTACGGCCGCACCCGACGAGATCCC
AGCGTTGGTGGCTGCGGATTCTCGCGAGACGTGGCGCGGAATGCGGCACACCGACTCGGATTACGTTGCGGCATATCGGG
TCAGCGCCAATGCCGAGTTGCCCGATACGTTGCCCGCGATCCGGTCGCGTCCGGCGCAGGAGACCTGGATCGCGCTGGAG
ATCGCATATGCCGCCGGGTCATCAACCCGCTACACGGTGGCCGCTGCCTGCGCATTGCGGACCGATTGGCGGCCTGGCGG
CACCGCACCGGTGGCCGGCCTGCTCCCGCAACACGGAAACCACGTGCCAGCCCTGACAGCCTTGGATCCGCGATCCACCC
GCCGACTCGACGGGCACACCGATGCTCCTGCCGACCTGCTGACCCGGCTGCACTGGCCTACTCCTACCGCCGGCGCCCAC
CGGGCACCGCTGACCAACGCCGTCAGTCGAACATGA

Upstream 100 bases:

>100_bases
CGCGCAACGTCGCATTCGCCGGAGCAGCCGCGCTGAGCGTGCTGGTCGGGCTCACAGCCGCGACTGTCGCGATAGCGCGC
CGACGAAGGGAGCCCACCGA

Downstream 100 bases:

>100_bases
GGCCCTGCAGGAACACGGTCATCCGCCGCAGATAGTCCAACTGGCTCACATGCAGCAGGTGGCTGCCGGGGAACCAGTGC
AGCGCACAGCGATCCCACTG

Product: putative transmembrane protein

Products: NA

Alternate protein names: ESX conserved component E3; Type VII secretion system protein EccE3; T7SS protein EccE3

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATC
TRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETA
QVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALE
IAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAH
RAPLTNAVSRT

Sequences:

>Translated_331_residues
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATC
TRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETA
QVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALE
IAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAH
RAPLTNAVSRT
>Mature_331_residues
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTIARRGLAILRRRRRIAEPATC
TRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRITSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETA
QVAARRLADHLREIGWEAGTAAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALE
IAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHTDAPADLLTRLHWPTPTAGAH
RAPLTNAVSRT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EccE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCE3_MYCTU (O53696)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   B70837
- RefSeq:   NP_214806.1
- RefSeq:   NP_334715.1
- EnsemblBacteria:   EBMYCT00000001094
- EnsemblBacteria:   EBMYCT00000069050
- GeneID:   886601
- GeneID:   923255
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0305
- KEGG:   mtu:Rv0292
- TIGR:   MT0305
- TubercuList:   Rv0292
- GeneTree:   EBGT00050000015326
- HOGENOM:   HBG564969
- OMA:   LIPQRGN
- ProtClustDB:   CLSK790409
- GO:   GO:0040007
- InterPro:   IPR021368

Pfam domain/function: PF11203 DUF2984

EC number: NA

Molecular weight: Translated: 35932; Mature: 35932

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b3f1d78)-; HASH(0x1c080f20)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGLAILRRRRRIAEPATCTRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRI
HHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
TSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETAQVAARRLADHLREIGWEAGT
EEEEECCCCCEEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
AAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALE
CCCCCCCEEEECCCHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCEEEEEE
IAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHT
EEEECCCCCCEEEEEEEHHCCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCCC
DAPADLLTRLHWPTPTAGAHRAPLTNAVSRT
CCHHHHHHHCCCCCCCCCCCCCCCCHHHCCH
>Mature Secondary Structure
MNPIPSWPGRGRVTLVLLAVVPVALAYPWQSTRDYVLLGVAAAVVIGLFGFWRGLYFTTI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGLAILRRRRRIAEPATCTRTTVLVWVGPPASDTNVLPLTLIARYLDRYGIRADTIRI
HHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
TSRVTASGDCRTWVGLTVVADDNLAALQARSARIPLQETAQVAARRLADHLREIGWEAGT
EEEEECCCCCEEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
AAPDEIPALVAADSRETWRGMRHTDSDYVAAYRVSANAELPDTLPAIRSRPAQETWIALE
CCCCCCCEEEECCCHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCEEEEEE
IAYAAGSSTRYTVAAACALRTDWRPGGTAPVAGLLPQHGNHVPALTALDPRSTRRLDGHT
EEEECCCCCCEEEEEEEHHCCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCCC
DAPADLLTRLHWPTPTAGAHRAPLTNAVSRT
CCHHHHHHHCCCCCCCCCCCCCCCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036