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The map label for this gene is yiaY [H]

Identifier: 148654093

GI number: 148654093

Start: 2863405

End: 2864691

Strand: Direct

Name: yiaY [H]

Synonym: PsycPRwf_2296

Alternate gene names: 148654093

Gene position: 2863405-2864691 (Clockwise)

Preceding gene: 148654089

Following gene: 148654095

Centisome position: 96.12

GC content: 46.93

Gene sequence:

>1287_bases
ATGCACGCAACCAAAGCGCTTAATGCCTTAAAGCTTCTTTCTCCTAATAGCATACAACATGCCGGCTACCTAGCTGTTGC
CAAGACCCGTGCCAAAGCTTTACATGCCTTTGCAATGGTCGCTCCCATTCCAAGACCTCAATTATTTATCGGCGAACAAT
CCTGTTATGAGCTGTGCGATTTGATGATTAATGAAGGCGCTACCAATGTACTAATCGTCACTGATGCGGTATTAAACCAG
TTGGGTGTTCCCGAAAAAGTCACTACTTATTTAGAAGATAAACGCGTCAGCTATCATTTGTTTGATGGTATTACGCCAGA
CCCTACCTTTAGCGTGGTAGAAGAAGGGTTGCGCCACTCTGTGGACAATCACTGTGATGCCATTTTGGCCATCGGCGGTG
GCTCGGTTATCGATGCCTCAAAAATTATTGCGATGAGTCAGGCCACCAAGCGCAAACCTCAACAATTAATGGGGTTATTA
AAAGCCTCTAAATGCATGCCTTTATATTGTATCCCCACCACAGCAGGTACCGGTTCTGAGGCAACATTAGGCGCGGTAAT
TTCAGATGACAAGACTCACCAAAAGTCTTTATCCATTGATCCACGCATGGTACCTCTAGCCTCAGCGGTAGACCCTGTGA
TTATGAAAGTCATGCCGCCCCACATTACTGCCGATACCGGTATTGATGTGCTAACCCATGCTTTAGAGGCGTGGATGAGT
GCCAATGCCAGCAGTGAGACTGACTACTATGCCGCCTCTGCCACTAGAACGGTGATGCAGTATCTGCCGCAAGCGTATAA
AGATGGCTCGGATCTAAAGGCTCGAGAAGAGATGGGTGTGGCTGCGCACTACGGCGGTATTGCTTTTAATAAGGCCGGCT
TGGGATATGTTCACGCCATCGCTCACCAGTTAGGGGCGTTCTATGGTATTCCTCATGGCCGTGCTAACGCCATCGTATTA
CCGCATATCTTAGAAATTAACCGAAAGGTATCACAGCACAGATTGGCGGCCTTGGCCAAAAAAGTAGGGATTTTAGGGGC
AGCTGATACCCATGCTGAAGACAGCGAGCTGACTGACCATTTGATTGCTAAAGTGAAAGCCTTAATTGCTTCTCTAAACA
TCGATGTCACGGTTAAAGGTATTGATCCGGCTGACTTCAAAAAGATGGCCAAAGCGGCTGCCAAAGAAGTCAGTGATACT
TATGCGGTGCCAAGATATCTGACCTCAGCACAGATTATTGATATTTTAAATGACATCAAGGCCGAAAGCGATGCGCTTGC
CAAATAA

Upstream 100 bases:

>100_bases
TTCTATCTTTTTTTTATAGTGGCACAATGTGATCACAAGCAATCAACTTATGTGCTTTGACCTATTTAAATCAGAACGAA
CCACTGAAAAGGATTTTTCT

Downstream 100 bases:

>100_bases
GCCTTAACTGCGCTTATCTGCTACTGATATGCTGGTATATAATGACATACAAAGCCCTTCACTTTTTGTGAGGGGCTTTT
TGTTTGGCTAACGCTTTTAG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MHATKALNALKLLSPNSIQHAGYLAVAKTRAKALHAFAMVAPIPRPQLFIGEQSCYELCDLMINEGATNVLIVTDAVLNQ
LGVPEKVTTYLEDKRVSYHLFDGITPDPTFSVVEEGLRHSVDNHCDAILAIGGGSVIDASKIIAMSQATKRKPQQLMGLL
KASKCMPLYCIPTTAGTGSEATLGAVISDDKTHQKSLSIDPRMVPLASAVDPVIMKVMPPHITADTGIDVLTHALEAWMS
ANASSETDYYAASATRTVMQYLPQAYKDGSDLKAREEMGVAAHYGGIAFNKAGLGYVHAIAHQLGAFYGIPHGRANAIVL
PHILEINRKVSQHRLAALAKKVGILGAADTHAEDSELTDHLIAKVKALIASLNIDVTVKGIDPADFKKMAKAAAKEVSDT
YAVPRYLTSAQIIDILNDIKAESDALAK

Sequences:

>Translated_428_residues
MHATKALNALKLLSPNSIQHAGYLAVAKTRAKALHAFAMVAPIPRPQLFIGEQSCYELCDLMINEGATNVLIVTDAVLNQ
LGVPEKVTTYLEDKRVSYHLFDGITPDPTFSVVEEGLRHSVDNHCDAILAIGGGSVIDASKIIAMSQATKRKPQQLMGLL
KASKCMPLYCIPTTAGTGSEATLGAVISDDKTHQKSLSIDPRMVPLASAVDPVIMKVMPPHITADTGIDVLTHALEAWMS
ANASSETDYYAASATRTVMQYLPQAYKDGSDLKAREEMGVAAHYGGIAFNKAGLGYVHAIAHQLGAFYGIPHGRANAIVL
PHILEINRKVSQHRLAALAKKVGILGAADTHAEDSELTDHLIAKVKALIASLNIDVTVKGIDPADFKKMAKAAAKEVSDT
YAVPRYLTSAQIIDILNDIKAESDALAK
>Mature_428_residues
MHATKALNALKLLSPNSIQHAGYLAVAKTRAKALHAFAMVAPIPRPQLFIGEQSCYELCDLMINEGATNVLIVTDAVLNQ
LGVPEKVTTYLEDKRVSYHLFDGITPDPTFSVVEEGLRHSVDNHCDAILAIGGGSVIDASKIIAMSQATKRKPQQLMGLL
KASKCMPLYCIPTTAGTGSEATLGAVISDDKTHQKSLSIDPRMVPLASAVDPVIMKVMPPHITADTGIDVLTHALEAWMS
ANASSETDYYAASATRTVMQYLPQAYKDGSDLKAREEMGVAAHYGGIAFNKAGLGYVHAIAHQLGAFYGIPHGRANAIVL
PHILEINRKVSQHRLAALAKKVGILGAADTHAEDSELTDHLIAKVKALIASLNIDVTVKGIDPADFKKMAKAAAKEVSDT
YAVPRYLTSAQIIDILNDIKAESDALAK

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=379, Percent_Identity=25.3298153034301, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI48994951, Length=369, Percent_Identity=37.3983739837398, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789163, Length=376, Percent_Identity=34.3085106382979, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87082107, Length=366, Percent_Identity=32.7868852459016, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1787493, Length=392, Percent_Identity=32.9081632653061, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1789386, Length=317, Percent_Identity=25.5520504731861, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17537053, Length=299, Percent_Identity=26.4214046822742, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=35.0923482849604, Blast_Score=206, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=23.6406619385343, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 45760; Mature: 45760

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHATKALNALKLLSPNSIQHAGYLAVAKTRAKALHAFAMVAPIPRPQLFIGEQSCYELCD
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHH
LMINEGATNVLIVTDAVLNQLGVPEKVTTYLEDKRVSYHLFDGITPDPTFSVVEEGLRHS
HHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
VDNHCDAILAIGGGSVIDASKIIAMSQATKRKPQQLMGLLKASKCMPLYCIPTTAGTGSE
HHCCCCEEEEECCCCEECHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
ATLGAVISDDKTHQKSLSIDPRMVPLASAVDPVIMKVMPPHITADTGIDVLTHALEAWMS
CEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ANASSETDYYAASATRTVMQYLPQAYKDGSDLKAREEMGVAAHYGGIAFNKAGLGYVHAI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEECCCEEECCCCCHHHHHH
AHQLGAFYGIPHGRANAIVLPHILEINRKVSQHRLAALAKKVGILGAADTHAEDSELTDH
HHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIAKVKALIASLNIDVTVKGIDPADFKKMAKAAAKEVSDTYAVPRYLTSAQIIDILNDIK
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AESDALAK
CCHHHCCC
>Mature Secondary Structure
MHATKALNALKLLSPNSIQHAGYLAVAKTRAKALHAFAMVAPIPRPQLFIGEQSCYELCD
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHH
LMINEGATNVLIVTDAVLNQLGVPEKVTTYLEDKRVSYHLFDGITPDPTFSVVEEGLRHS
HHHCCCCCEEEEEEHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
VDNHCDAILAIGGGSVIDASKIIAMSQATKRKPQQLMGLLKASKCMPLYCIPTTAGTGSE
HHCCCCEEEEECCCCEECHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
ATLGAVISDDKTHQKSLSIDPRMVPLASAVDPVIMKVMPPHITADTGIDVLTHALEAWMS
CEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ANASSETDYYAASATRTVMQYLPQAYKDGSDLKAREEMGVAAHYGGIAFNKAGLGYVHAI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEECCCEEECCCCCHHHHHH
AHQLGAFYGIPHGRANAIVLPHILEINRKVSQHRLAALAKKVGILGAADTHAEDSELTDH
HHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIAKVKALIASLNIDVTVKGIDPADFKKMAKAAAKEVSDTYAVPRYLTSAQIIDILNDIK
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AESDALAK
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]