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The map label for this gene is corC [H]

Identifier: 148654044

GI number: 148654044

Start: 2791390

End: 2792280

Strand: Direct

Name: corC [H]

Synonym: PsycPRwf_2247

Alternate gene names: 148654044

Gene position: 2791390-2792280 (Clockwise)

Preceding gene: 148654042

Following gene: 148654045

Centisome position: 93.7

GC content: 47.92

Gene sequence:

>891_bases
ATGTCTGATGACAATTCTGGCACAACCAGCTGGTCCATGCGCGGCTTAAAGCGCTGGCTTCATACTGCCCCCGAAACCCG
GGACGAGCTGATAAAATTGGTCCAAAACTCACGCCAGTTTTTAGAAGCCGATACCGTAGATATGCTGGAAGGGGTGCTTG
ACCTACCCGCCACGCAAGTTCGTGAGATTATGACCCCGCGTCCTCAAGTCGAGGGAGTTCGTGAGCATGATACTCTAGGC
GATATTATGGACATGATCATGAAGACCAGTCATTCACGCTATCCGGTGTTTGACAGTCAAGATGATGATGCCGTCATTGG
TATCTTATTGGCCAAAGACCTAATTCCTTTGCTGGTCAACATGATTCGTCAAGATGAAGATGCAGATACTTCTTTTCGCC
TAAAGTCATTGATCCGTCAACCTTTATATATCAGCGAAACCGCACGCTCTGACACGCTGTTGCGCTCACTACAGCGTACT
CAAGTGCACATGGCTGTTGTGGTCGATGAGTTTGGTAACATGGTGGGCGTGGTCACGATGGAGGACTTGCTCGAAGAAAT
CGTCGGTGACATTGTTGATGAGCACGATGACTTTGAAGAAGACAGTGACATCAATAACATCATTCCTCACCCTGAAAAAC
CCAATACTTGGATTGTTCAGGCCTCAACCCTCATTGAAGACTGCAATGAAGAGCTAAATGCTAATTTTGATGACACCGAC
GTTGATACCATGGGCGGGCTAGTCATGCAGGAGCTGGGCTATGTGGGCGACTTAGAAGGTGAAAGCGTGACTACTCAAGG
CTGGCACATCTCCATCATTGATGTGGAAGGACGCTTTATCAAACTGCTTGAATTAACCCCCGTGGCTGAAGACTTATACA
ATGAGGACTAG

Upstream 100 bases:

>100_bases
CAAAATAGACGAGAAAATAGTAGCCTTGGGCGTTGAATATAAATGCACCTTGGGATAAAGTGAGAGCAACTAAATAACCA
TACGAGGTGATACTCCCCCC

Downstream 100 bases:

>100_bases
AGCTGGCTTGCCTTTTAATGGCCAAAAGACCGGCTTAGCCTGTGTAGCGGTCATGGCCTCTACGCTGCTGGTGAGCGCTT
GTCACACCTCATCTGTCGCT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSDDNSGTTSWSMRGLKRWLHTAPETRDELIKLVQNSRQFLEADTVDMLEGVLDLPATQVREIMTPRPQVEGVREHDTLG
DIMDMIMKTSHSRYPVFDSQDDDAVIGILLAKDLIPLLVNMIRQDEDADTSFRLKSLIRQPLYISETARSDTLLRSLQRT
QVHMAVVVDEFGNMVGVVTMEDLLEEIVGDIVDEHDDFEEDSDINNIIPHPEKPNTWIVQASTLIEDCNEELNANFDDTD
VDTMGGLVMQELGYVGDLEGESVTTQGWHISIIDVEGRFIKLLELTPVAEDLYNED

Sequences:

>Translated_296_residues
MSDDNSGTTSWSMRGLKRWLHTAPETRDELIKLVQNSRQFLEADTVDMLEGVLDLPATQVREIMTPRPQVEGVREHDTLG
DIMDMIMKTSHSRYPVFDSQDDDAVIGILLAKDLIPLLVNMIRQDEDADTSFRLKSLIRQPLYISETARSDTLLRSLQRT
QVHMAVVVDEFGNMVGVVTMEDLLEEIVGDIVDEHDDFEEDSDINNIIPHPEKPNTWIVQASTLIEDCNEELNANFDDTD
VDTMGGLVMQELGYVGDLEGESVTTQGWHISIIDVEGRFIKLLELTPVAEDLYNED
>Mature_295_residues
SDDNSGTTSWSMRGLKRWLHTAPETRDELIKLVQNSRQFLEADTVDMLEGVLDLPATQVREIMTPRPQVEGVREHDTLGD
IMDMIMKTSHSRYPVFDSQDDDAVIGILLAKDLIPLLVNMIRQDEDADTSFRLKSLIRQPLYISETARSDTLLRSLQRTQ
VHMAVVVDEFGNMVGVVTMEDLLEEIVGDIVDEHDDFEEDSDINNIIPHPEKPNTWIVQASTLIEDCNEELNANFDDTDV
DTMGGLVMQELGYVGDLEGESVTTQGWHISIIDVEGRFIKLLELTPVAEDLYNED

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=203, Percent_Identity=30.5418719211823, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786879, Length=289, Percent_Identity=40.1384083044983, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI145693175, Length=265, Percent_Identity=27.1698113207547, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082033, Length=258, Percent_Identity=25.5813953488372, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788119, Length=229, Percent_Identity=27.9475982532751, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790664, Length=246, Percent_Identity=25.609756097561, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324512, Length=163, Percent_Identity=33.1288343558282, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33491; Mature: 33360

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDNSGTTSWSMRGLKRWLHTAPETRDELIKLVQNSRQFLEADTVDMLEGVLDLPATQV
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
REIMTPRPQVEGVREHDTLGDIMDMIMKTSHSRYPVFDSQDDDAVIGILLAKDLIPLLVN
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIRQDEDADTSFRLKSLIRQPLYISETARSDTLLRSLQRTQVHMAVVVDEFGNMVGVVTM
HHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHH
EDLLEEIVGDIVDEHDDFEEDSDINNIIPHPEKPNTWIVQASTLIEDCNEELNANFDDTD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCC
VDTMGGLVMQELGYVGDLEGESVTTQGWHISIIDVEGRFIKLLELTPVAEDLYNED
HHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCHHHHHHCCCC
>Mature Secondary Structure 
SDDNSGTTSWSMRGLKRWLHTAPETRDELIKLVQNSRQFLEADTVDMLEGVLDLPATQV
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
REIMTPRPQVEGVREHDTLGDIMDMIMKTSHSRYPVFDSQDDDAVIGILLAKDLIPLLVN
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIRQDEDADTSFRLKSLIRQPLYISETARSDTLLRSLQRTQVHMAVVVDEFGNMVGVVTM
HHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHH
EDLLEEIVGDIVDEHDDFEEDSDINNIIPHPEKPNTWIVQASTLIEDCNEELNANFDDTD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCC
VDTMGGLVMQELGYVGDLEGESVTTQGWHISIIDVEGRFIKLLELTPVAEDLYNED
HHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]