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The map label for this gene is yycF [H]

Identifier: 148653957

GI number: 148653957

Start: 2696359

End: 2697081

Strand: Direct

Name: yycF [H]

Synonym: PsycPRwf_2160

Alternate gene names: 148653957

Gene position: 2696359-2697081 (Clockwise)

Preceding gene: 148653951

Following gene: 148653958

Centisome position: 90.51

GC content: 47.03

Gene sequence:

>723_bases
ATGAGCAAGCAAATACTCCTGATCGAAGATGATCCTGATTTAGCAGAATTAATTAGCGATTACTTGGCAATGAATTATTA
TGAGGTGCACCATGCGCCCACAGGTCAAGAAGGTCTTGATATTCTTGATGCCAAAGAACGCGCCATCGACTTAATTATCC
TAGACTTAATGCTACCGGATATGGATGGCATGCAGGTTTGCCAAAAAATCCGTGGCGGTAAAAATAGCCAAACCAATAAA
GTGCCTATCGTTATGTTAACCGCCAAAGGCGATACGACCGACCGAGTACTGGGTCTGGAGATGGGCGCAGACGATTATAT
TTCAAAGCCATTCGAGCCTCGTGAGCTGTTGGCTCGTATTCGTGCCGTACTGCGTCGTCATGAGCAGCCAAATCAAGCTG
ACAGCCAGTCTGACAGCTTAACGTTTGGCCGCTTAAGCGTATTCCCTGATAGTCATGAAGTCACCATTGATGACAAGCCT
GTCCGTTTAACCACCCATCAATTCCAGCTGCTCCACTACTTCGCCACCCATGCAGGCAAGGTATTAAACCGTGAGCAGTT
GTGGCAAGCCATGCCCAATGATGACAGCTCAGATAACATTGATCGCGCAATTGACGTGCACATCTCAAGACTGCGTGCAT
TAATTGAAGACAACCCACGTCAGCCTAAACGCATCATTACTGTGCGCGGTGTCGGCTATCAATTTGCTACCGATCAAGTT
TAA

Upstream 100 bases:

>100_bases
CTAACTTAAAACAGCCGCCCAAGCTGTTAATAACCAATAATCATCACAAAATTAACAGCCAAGCCAGATGATTCAATTTT
TATAATTTTTAAGGATAGTT

Downstream 100 bases:

>100_bases
TTCGGTTCGATATTCTACAATTGATATTCTACGGTTGATATCTACCATCCATTGAGGGTCTAAGCACAACCGGTTGGCTT
AGACCCTCAATTACTCTCAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSKQILLIEDDPDLAELISDYLAMNYYEVHHAPTGQEGLDILDAKERAIDLIILDLMLPDMDGMQVCQKIRGGKNSQTNK
VPIVMLTAKGDTTDRVLGLEMGADDYISKPFEPRELLARIRAVLRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDKP
VRLTTHQFQLLHYFATHAGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV

Sequences:

>Translated_240_residues
MSKQILLIEDDPDLAELISDYLAMNYYEVHHAPTGQEGLDILDAKERAIDLIILDLMLPDMDGMQVCQKIRGGKNSQTNK
VPIVMLTAKGDTTDRVLGLEMGADDYISKPFEPRELLARIRAVLRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDKP
VRLTTHQFQLLHYFATHAGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
>Mature_239_residues
SKQILLIEDDPDLAELISDYLAMNYYEVHHAPTGQEGLDILDAKERAIDLIILDLMLPDMDGMQVCQKIRGGKNSQTNKV
PIVMLTAKGDTTDRVLGLEMGADDYISKPFEPRELLARIRAVLRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDKPV
RLTTHQFQLLHYFATHAGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=40.9282700421941, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786599, Length=241, Percent_Identity=39.8340248962656, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=38.3966244725738, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=39.9141630901288, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=236, Percent_Identity=39.4067796610169, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=39.7489539748954, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786784, Length=242, Percent_Identity=39.2561983471074, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=33.1896551724138, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.4827586206897, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=240, Percent_Identity=30.8333333333333, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=31.1203319502075, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790552, Length=236, Percent_Identity=33.8983050847458, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=32.1888412017167, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787375, Length=188, Percent_Identity=32.9787234042553, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=28.3185840707965, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27242; Mature: 27111

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQILLIEDDPDLAELISDYLAMNYYEVHHAPTGQEGLDILDAKERAIDLIILDLMLPD
CCCCEEEEECCCCHHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHHHEEEHHCCC
MDGMQVCQKIRGGKNSQTNKVPIVMLTAKGDTTDRVLGLEMGADDYISKPFEPRELLARI
CCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCHHHHCCCCCHHHHHHHH
RAVLRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDKPVRLTTHQFQLLHYFATHAGK
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHH
VLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
HCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCC
>Mature Secondary Structure 
SKQILLIEDDPDLAELISDYLAMNYYEVHHAPTGQEGLDILDAKERAIDLIILDLMLPD
CCCEEEEECCCCHHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHHHEEEHHCCC
MDGMQVCQKIRGGKNSQTNKVPIVMLTAKGDTTDRVLGLEMGADDYISKPFEPRELLARI
CCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCHHHHCCCCCHHHHHHHH
RAVLRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDKPVRLTTHQFQLLHYFATHAGK
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHH
VLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
HCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]