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The map label for this gene is ipk

Identifier: 148653901

GI number: 148653901

Start: 2626207

End: 2627178

Strand: Direct

Name: ipk

Synonym: PsycPRwf_2104

Alternate gene names: 148653901

Gene position: 2626207-2627178 (Clockwise)

Preceding gene: 148653900

Following gene: 148653902

Centisome position: 88.16

GC content: 49.69

Gene sequence:

>972_bases
ATGACCTCGTATGCCAAGCTTAGTTTATTTTCACCGGCGAAAATCAATCTGTTTTTGCACATTACCGGTAAAAGAGCAGA
TGGCTATCATAACTTGCAGACGGTGTTTCGTTTGCTAGACTGGGGTGATACCCTAGAGTTCTTGGTCACCCAGGATAGCT
TCGATCCTACAGCGCCGATTAATGAGCAGCACTTACTGGTTCGCTTAAGTAGCACAGTGGCCATCACCGCACAGGTGATG
GACAACTTGGTCATCAAAGCGGCTGTGGCGCTGCTACAGGCATGGCAAAACAGTGCCCTCACACGGTCATCTGACCCCGC
GGTAACCCCTCACCTGCCGGTTATCGAAGTGACGCTCAACAAAGTTCTACCAACTGGCGCAGGCCTTGGTGGCGGCTCCT
CAAATGCAGCCACTACCTTAATAGCGCTAAATAAGCTATGGGGCTTTCATTATGACATTGAGGCTTTAATCAAGATTGGC
GCAACGGTCGGCGCTGATGTGCCAATTTTTGTGCTTGGGCAAGATGCCATTGCTGAGGGCATCGGCGAGCGGCTAACCCC
CATCAAGTTGCCACAGCATCAATATTTGCTATTAAATCCTGCAGCTCATGCAGCAACCCAAGCCCTATTTGCCCACCCTG
ACTTGCAGCGCAATGTGCCCGCATTAAGCATAGATGAGATAAAAGCGGCACAATCTTGCTACTTGCAGCAGCTTAATGCG
CCATTTAGCAATGTATTTGAGCCGGTGGTGACCAAGTTGGTGCCTGAGGTGAATCAGGCACTCAATTATCTTAGACAGCT
TGAGGCGCTCACCGGCACCCAAGCACGTATGACCGGTACCGGCAGCAGTGTATTTTTGCCGATACCTACTGACAAAATCA
GCCTCATAACACATCACCTTAGCAATGCTGGGGCGCCTTGTGATTATGTACTGACCCAAAGTTTAGATAAAAACGGGCAA
AACCCTGAATAA

Upstream 100 bases:

>100_bases
AGTTATCTTGACCATAGCGCACGATAAATAACCAATAAATTTGCGTCCAATTCACTGTTGAAGCAGATACGTTAATAGCC
TTTTGTAAGAAGACTGTATT

Downstream 100 bases:

>100_bases
TTTGGCAAAATTGCTACTTAAAGGCTGCCTAAATGCAGGGCACCCTGCTGTTTTAAACCCTGGTAATTTCCATCAAAAAT
AATATCTTTTAAATTAGTAT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTSYAKLSLFSPAKINLFLHITGKRADGYHNLQTVFRLLDWGDTLEFLVTQDSFDPTAPINEQHLLVRLSSTVAITAQVM
DNLVIKAAVALLQAWQNSALTRSSDPAVTPHLPVIEVTLNKVLPTGAGLGGGSSNAATTLIALNKLWGFHYDIEALIKIG
ATVGADVPIFVLGQDAIAEGIGERLTPIKLPQHQYLLLNPAAHAATQALFAHPDLQRNVPALSIDEIKAAQSCYLQQLNA
PFSNVFEPVVTKLVPEVNQALNYLRQLEALTGTQARMTGTGSSVFLPIPTDKISLITHHLSNAGAPCDYVLTQSLDKNGQ
NPE

Sequences:

>Translated_323_residues
MTSYAKLSLFSPAKINLFLHITGKRADGYHNLQTVFRLLDWGDTLEFLVTQDSFDPTAPINEQHLLVRLSSTVAITAQVM
DNLVIKAAVALLQAWQNSALTRSSDPAVTPHLPVIEVTLNKVLPTGAGLGGGSSNAATTLIALNKLWGFHYDIEALIKIG
ATVGADVPIFVLGQDAIAEGIGERLTPIKLPQHQYLLLNPAAHAATQALFAHPDLQRNVPALSIDEIKAAQSCYLQQLNA
PFSNVFEPVVTKLVPEVNQALNYLRQLEALTGTQARMTGTGSSVFLPIPTDKISLITHHLSNAGAPCDYVLTQSLDKNGQ
NPE
>Mature_322_residues
TSYAKLSLFSPAKINLFLHITGKRADGYHNLQTVFRLLDWGDTLEFLVTQDSFDPTAPINEQHLLVRLSSTVAITAQVMD
NLVIKAAVALLQAWQNSALTRSSDPAVTPHLPVIEVTLNKVLPTGAGLGGGSSNAATTLIALNKLWGFHYDIEALIKIGA
TVGADVPIFVLGQDAIAEGIGERLTPIKLPQHQYLLLNPAAHAATQALFAHPDLQRNVPALSIDEIKAAQSCYLQQLNAP
FSNVFEPVVTKLVPEVNQALNYLRQLEALTGTQARMTGTGSSVFLPIPTDKISLITHHLSNAGAPCDYVLTQSLDKNGQN
PE

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=39.5017793594306, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPE_PSYWF (A5WHA3)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280994.1
- ProteinModelPortal:   A5WHA3
- SMR:   A5WHA3
- STRING:   A5WHA3
- GeneID:   5206036
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_2104
- eggNOG:   COG1947
- HOGENOM:   HBG734593
- OMA:   LNLFLHV
- ProtClustDB:   PRK00343
- BioCyc:   PSP56811:PSYCPRWF_2104-MONOMER
- HAMAP:   MF_00061
- InterPro:   IPR006204
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721
- Gene3D:   G3DSA:3.30.230.10
- PANTHER:   PTHR20861:SF2
- PIRSF:   PIRSF010376
- TIGRFAMs:   TIGR00154

Pfam domain/function: PF00288 GHMP_kinases_N; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.1.148

Molecular weight: Translated: 34808; Mature: 34677

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: ACT_SITE 14-14 ACT_SITE 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYAKLSLFSPAKINLFLHITGKRADGYHNLQTVFRLLDWGDTLEFLVTQDSFDPTAPI
CCCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
NEQHLLVRLSSTVAITAQVMDNLVIKAAVALLQAWQNSALTRSSDPAVTPHLPVIEVTLN
CCCEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHH
KVLPTGAGLGGGSSNAATTLIALNKLWGFHYDIEALIKIGATVGADVPIFVLGQDAIAEG
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHH
IGERLTPIKLPQHQYLLLNPAAHAATQALFAHPDLQRNVPALSIDEIKAAQSCYLQQLNA
HHHCCCCEECCCCCEEEECCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHCC
PFSNVFEPVVTKLVPEVNQALNYLRQLEALTGTQARMTGTGSSVFLPIPTDKISLITHHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHH
SNAGAPCDYVLTQSLDKNGQNPE
HCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSYAKLSLFSPAKINLFLHITGKRADGYHNLQTVFRLLDWGDTLEFLVTQDSFDPTAPI
CCCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
NEQHLLVRLSSTVAITAQVMDNLVIKAAVALLQAWQNSALTRSSDPAVTPHLPVIEVTLN
CCCEEEEEECCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHH
KVLPTGAGLGGGSSNAATTLIALNKLWGFHYDIEALIKIGATVGADVPIFVLGQDAIAEG
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHH
IGERLTPIKLPQHQYLLLNPAAHAATQALFAHPDLQRNVPALSIDEIKAAQSCYLQQLNA
HHHCCCCEECCCCCEEEECCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHCC
PFSNVFEPVVTKLVPEVNQALNYLRQLEALTGTQARMTGTGSSVFLPIPTDKISLITHHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHH
SNAGAPCDYVLTQSLDKNGQNPE
HCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA