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The map label for this gene is dsbC [H]

Identifier: 148653806

GI number: 148653806

Start: 2500877

End: 2501710

Strand: Direct

Name: dsbC [H]

Synonym: PsycPRwf_2009

Alternate gene names: 148653806

Gene position: 2500877-2501710 (Clockwise)

Preceding gene: 148653805

Following gene: 148653807

Centisome position: 83.95

GC content: 49.76

Gene sequence:

>834_bases
ATGACCCCTTTATTTCACCAAAACTTATTAAAAAAATCACCCGCTTTCACCAAAGCGTCATTGATGGCATTGGCCATCGC
CGTCGCTGGCTGTAACAGCAACAGCACTGAAGCTAGAAACGAGCCGAGCAAGACGCCCACGAGCGCCAAGCAAAATACCA
GTGCCAGTTCTGACTCTGATCCGAAGGTAGTGGCCGCGTTAGAAGCCAACTTTAAGGCCTCAGGTTTTGAGCAAAAAATC
ATCTCGGCCATCCCCACCTCAATGGACAATATTTATTGGGTGACTGCCGAGGGCATGCCCGCCTTTTTTAGTGATAAAGA
AGGTAGGCACATCATTCAAGGACAGATTGTCGAGATTGGTCAAGCGCATCCGGTTGATATCAGTGCCGACTTGATAGCAC
AGAGCGCCAAGCAAAAACTGGCAGCCGTGGATAAAAAAGAGATGATTATTTATCCGGCCAAAGGCGCCACCAAAGCTGTG
GTCTATGTCTTTACCGATGCCGACTGCCCTTATTGCACCAAATTGCATTCTGAAATGAGTGATATCAATGCCCAAGGGAT
AGAGGTGCGTTATCTTGCTTGGCCACGCAGTGATGCCAGTATTCCAAAAATGGAAGCCATCTGGTGTAGCAGTGACCGTA
TGCAGGCCATGGACGACGCCAAAGCCGGTAAGCCATTATCCTCGCCTAAGTGTGATAGCCCTGTTCGTTCACACATTGAG
CTGGGTATGAGCTTAGGCGTGAGTGGCACACCTGCTATCTTTACCGAATCTGGTCATCAAATTGGCGGCTATTTGCCTGC
CAAAGAGCTGGCCGCCGCCGCCCTTGCTCACTAA

Upstream 100 bases:

>100_bases
GGGGCTTTTGTTTATCTCAATTCTATCACCGATATAATATGCTAAACTGAGCGCTGCTTGTTAACTTCATTTGAGCATTA
TCCGCTAAGAGACACCTGTT

Downstream 100 bases:

>100_bases
GATTCTGATAACAGATAAAGGCTGTGCTCAAGTCAGTATCTGATGCTTTGTCTAGTCGATGAGTTAACACTTTATTCACC
TAGCATTGGCTGCTAATATA

Product: protein-disulfide isomerase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTPLFHQNLLKKSPAFTKASLMALAIAVAGCNSNSTEARNEPSKTPTSAKQNTSASSDSDPKVVAALEANFKASGFEQKI
ISAIPTSMDNIYWVTAEGMPAFFSDKEGRHIIQGQIVEIGQAHPVDISADLIAQSAKQKLAAVDKKEMIIYPAKGATKAV
VYVFTDADCPYCTKLHSEMSDINAQGIEVRYLAWPRSDASIPKMEAIWCSSDRMQAMDDAKAGKPLSSPKCDSPVRSHIE
LGMSLGVSGTPAIFTESGHQIGGYLPAKELAAAALAH

Sequences:

>Translated_277_residues
MTPLFHQNLLKKSPAFTKASLMALAIAVAGCNSNSTEARNEPSKTPTSAKQNTSASSDSDPKVVAALEANFKASGFEQKI
ISAIPTSMDNIYWVTAEGMPAFFSDKEGRHIIQGQIVEIGQAHPVDISADLIAQSAKQKLAAVDKKEMIIYPAKGATKAV
VYVFTDADCPYCTKLHSEMSDINAQGIEVRYLAWPRSDASIPKMEAIWCSSDRMQAMDDAKAGKPLSSPKCDSPVRSHIE
LGMSLGVSGTPAIFTESGHQIGGYLPAKELAAAALAH
>Mature_276_residues
TPLFHQNLLKKSPAFTKASLMALAIAVAGCNSNSTEARNEPSKTPTSAKQNTSASSDSDPKVVAALEANFKASGFEQKII
SAIPTSMDNIYWVTAEGMPAFFSDKEGRHIIQGQIVEIGQAHPVDISADLIAQSAKQKLAAVDKKEMIIYPAKGATKAVV
YVFTDADCPYCTKLHSEMSDINAQGIEVRYLAWPRSDASIPKMEAIWCSSDRMQAMDDAKAGKPLSSPKCDSPVRSHIEL
GMSLGVSGTPAIFTESGHQIGGYLPAKELAAAALAH

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=173, Percent_Identity=43.3526011560694, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 29558; Mature: 29427

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLFHQNLLKKSPAFTKASLMALAIAVAGCNSNSTEARNEPSKTPTSAKQNTSASSDSD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKVVAALEANFKASGFEQKIISAIPTSMDNIYWVTAEGMPAFFSDKEGRHIIQGQIVEIG
CEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEECC
QAHPVDISADLIAQSAKQKLAAVDKKEMIIYPAKGATKAVVYVFTDADCPYCTKLHSEMS
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
DINAQGIEVRYLAWPRSDASIPKMEAIWCSSDRMQAMDDAKAGKPLSSPKCDSPVRSHIE
HCCCCCEEEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LGMSLGVSGTPAIFTESGHQIGGYLPAKELAAAALAH
HHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TPLFHQNLLKKSPAFTKASLMALAIAVAGCNSNSTEARNEPSKTPTSAKQNTSASSDSD
CCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKVVAALEANFKASGFEQKIISAIPTSMDNIYWVTAEGMPAFFSDKEGRHIIQGQIVEIG
CEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEECCEEEECC
QAHPVDISADLIAQSAKQKLAAVDKKEMIIYPAKGATKAVVYVFTDADCPYCTKLHSEMS
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHH
DINAQGIEVRYLAWPRSDASIPKMEAIWCSSDRMQAMDDAKAGKPLSSPKCDSPVRSHIE
HCCCCCEEEEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LGMSLGVSGTPAIFTESGHQIGGYLPAKELAAAALAH
HHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609; 9370270 [H]