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The map label for this gene is mltB [H]

Identifier: 148653769

GI number: 148653769

Start: 2456988

End: 2458448

Strand: Direct

Name: mltB [H]

Synonym: PsycPRwf_1972

Alternate gene names: 148653769

Gene position: 2456988-2458448 (Clockwise)

Preceding gene: 148653768

Following gene: 148653773

Centisome position: 82.48

GC content: 48.67

Gene sequence:

>1461_bases
ATGTCATCCACTAAGTTATCTGCTGTGTTTCCTGTATTATCCACACTAGGGCTTGCCAGCCTAGTTTTTATTGCACCTAC
CAGTTATGCTGAGCAAAAGCCGTTACCCACTCTGGATAACAACCAGTTTAATGTGTGTTTAGATAATCTGAGCCAGTCCT
CAGCTTTTGCCAGTGTTAAAGACACTTTGGCTCAGTATCGCCCGGCACAAGGCGACCCTAGCGTGTTAGAGTCGCTCGAT
TATCAACCTGAATTTCAAAAAGAGCCTTGGGATTATCTGGCAAGCTTGGTAGACGAAGAGCGGGTTATCGATGGCATTGC
GGCCAGTGAGCGTTATGCCGATGTCTTAGCACGTATTGAAGCGCAATACGGTGTCAACCGTTACGATGTGCTTGGCGTGT
GGGGCGTTGAATCTGACTTTGGAACTACCCTTGGCAAAAAAGAGGTGGTGCAGTCCTTGGCTACCTTATCTTGCTTTGGT
CGCCGCCAAAGCTATTTTCGCAGTGAATATGTCAGCGCCCTAAAAATCTTAAAGCAAGGCGACATTGCCCCCAATGACTT
TAAAGGCTCTTGGGCGGGTGCATTTGGGCAGACCCAATTTATGCCCTCAACCTTCTTGCAACTGGCACAAGACTTCGATG
GTGATGGCCGAAAAGACTTGGTCAATAGCCAAGCCGATGCCCTAGCCTCCACCGCCAACTTCTTAAAAAACAGTGGCTAT
CAGTCTGGACAACCTTGGGGCTATGAGGTGCGCTTACCGGCCAATATTAATGCCAGCAATGATCGCAAAAACAAACAGCC
CATTTCGCATTGGCGCAACTTAGGCATTACCTTGGTCGATGGCAGTGAGCTGTCTGATTCACTCAGCAATGCAGGCTTGT
TGTTACCCGCCGGCAAAAATGGCCCCGCTTTCTTAGTCGGTCGTAATTTCGATGCGTTTTATGCCTACAATGCTTCTGAG
AACTATGCATTAGCCATTGCTCATTTGTCTGATCGTATTGAGCAGCAAAACACCGATGTGGACTTTGCTACGCCTTGGCC
AACTGATGATCCAGGCTTAAGCCGTAAACAGTCTCGAGAGCTGCAGCAGGCGCTTAATTTATTGGGTTATGATATTGGCG
AAGTTGATGGCATCATCGGTGATGGTACCCGCCGCGCCATTCAGCAATATCAGACCGATAATGGCTTAACCCCCGATGGC
AGAGCCGGTAAAAAAATCCATCAGCATTTGATGCACGTTACCGCCAATATGCCGCAGCATGAGAGTGAGCCCGCTGATGA
GGCGCAGCATACAGCCGATGATGATCAATTGGCTACCGGCAATGCCCACAGTGCCAGCAAAAAAATCAGCGAAACCAAGT
CGGGTCTGAGTAAGTTGCTGCAAATTAAAAGCCTAACGGCCATCTTGATAGGCCTGTTTATTGTGCTGGTCATTGCACTG
GTGAGTAGACGCAAACGCTAA

Upstream 100 bases:

>100_bases
GCTGACAGATAAGCGTTACAAAGCTGAAACTCTTTGTTTCAAATCGTAGCTTATCTGCTAATATATAGGTTTAGATTTTA
TTACTACTGAGCCTGTTGCC

Downstream 100 bases:

>100_bases
TGGCGACACGTTTTTGAGTTTCGTTGGTTGTTAATGAAATAGGTTGATTGATGTTGAAATATGAATAGCAAAATGCCAGG
CGAGTTTAAGCCTGGCATTT

Product: lytic murein transglycosylase

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSSTKLSAVFPVLSTLGLASLVFIAPTSYAEQKPLPTLDNNQFNVCLDNLSQSSAFASVKDTLAQYRPAQGDPSVLESLD
YQPEFQKEPWDYLASLVDEERVIDGIAASERYADVLARIEAQYGVNRYDVLGVWGVESDFGTTLGKKEVVQSLATLSCFG
RRQSYFRSEYVSALKILKQGDIAPNDFKGSWAGAFGQTQFMPSTFLQLAQDFDGDGRKDLVNSQADALASTANFLKNSGY
QSGQPWGYEVRLPANINASNDRKNKQPISHWRNLGITLVDGSELSDSLSNAGLLLPAGKNGPAFLVGRNFDAFYAYNASE
NYALAIAHLSDRIEQQNTDVDFATPWPTDDPGLSRKQSRELQQALNLLGYDIGEVDGIIGDGTRRAIQQYQTDNGLTPDG
RAGKKIHQHLMHVTANMPQHESEPADEAQHTADDDQLATGNAHSASKKISETKSGLSKLLQIKSLTAILIGLFIVLVIAL
VSRRKR

Sequences:

>Translated_486_residues
MSSTKLSAVFPVLSTLGLASLVFIAPTSYAEQKPLPTLDNNQFNVCLDNLSQSSAFASVKDTLAQYRPAQGDPSVLESLD
YQPEFQKEPWDYLASLVDEERVIDGIAASERYADVLARIEAQYGVNRYDVLGVWGVESDFGTTLGKKEVVQSLATLSCFG
RRQSYFRSEYVSALKILKQGDIAPNDFKGSWAGAFGQTQFMPSTFLQLAQDFDGDGRKDLVNSQADALASTANFLKNSGY
QSGQPWGYEVRLPANINASNDRKNKQPISHWRNLGITLVDGSELSDSLSNAGLLLPAGKNGPAFLVGRNFDAFYAYNASE
NYALAIAHLSDRIEQQNTDVDFATPWPTDDPGLSRKQSRELQQALNLLGYDIGEVDGIIGDGTRRAIQQYQTDNGLTPDG
RAGKKIHQHLMHVTANMPQHESEPADEAQHTADDDQLATGNAHSASKKISETKSGLSKLLQIKSLTAILIGLFIVLVIAL
VSRRKR
>Mature_485_residues
SSTKLSAVFPVLSTLGLASLVFIAPTSYAEQKPLPTLDNNQFNVCLDNLSQSSAFASVKDTLAQYRPAQGDPSVLESLDY
QPEFQKEPWDYLASLVDEERVIDGIAASERYADVLARIEAQYGVNRYDVLGVWGVESDFGTTLGKKEVVQSLATLSCFGR
RQSYFRSEYVSALKILKQGDIAPNDFKGSWAGAFGQTQFMPSTFLQLAQDFDGDGRKDLVNSQADALASTANFLKNSGYQ
SGQPWGYEVRLPANINASNDRKNKQPISHWRNLGITLVDGSELSDSLSNAGLLLPAGKNGPAFLVGRNFDAFYAYNASEN
YALAIAHLSDRIEQQNTDVDFATPWPTDDPGLSRKQSRELQQALNLLGYDIGEVDGIIGDGTRRAIQQYQTDNGLTPDGR
AGKKIHQHLMHVTANMPQHESEPADEAQHTADDDQLATGNAHSASKKISETKSGLSKLLQIKSLTAILIGLFIVLVIALV
SRRKR

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=246, Percent_Identity=32.9268292682927, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 53175; Mature: 53044

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTKLSAVFPVLSTLGLASLVFIAPTSYAEQKPLPTLDNNQFNVCLDNLSQSSAFASVK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
DTLAQYRPAQGDPSVLESLDYQPEFQKEPWDYLASLVDEERVIDGIAASERYADVLARIE
HHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYGVNRYDVLGVWGVESDFGTTLGKKEVVQSLATLSCFGRRQSYFRSEYVSALKILKQG
HHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DIAPNDFKGSWAGAFGQTQFMPSTFLQLAQDFDGDGRKDLVNSQADALASTANFLKNSGY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QSGQPWGYEVRLPANINASNDRKNKQPISHWRNLGITLVDGSELSDSLSNAGLLLPAGKN
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHCCCCEEEECCCC
GPAFLVGRNFDAFYAYNASENYALAIAHLSDRIEQQNTDVDFATPWPTDDPGLSRKQSRE
CCEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
LQQALNLLGYDIGEVDGIIGDGTRRAIQQYQTDNGLTPDGRAGKKIHQHLMHVTANMPQH
HHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
ESEPADEAQHTADDDQLATGNAHSASKKISETKSGLSKLLQIKSLTAILIGLFIVLVIAL
CCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRRKR
HHHCCC
>Mature Secondary Structure 
SSTKLSAVFPVLSTLGLASLVFIAPTSYAEQKPLPTLDNNQFNVCLDNLSQSSAFASVK
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
DTLAQYRPAQGDPSVLESLDYQPEFQKEPWDYLASLVDEERVIDGIAASERYADVLARIE
HHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYGVNRYDVLGVWGVESDFGTTLGKKEVVQSLATLSCFGRRQSYFRSEYVSALKILKQG
HHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DIAPNDFKGSWAGAFGQTQFMPSTFLQLAQDFDGDGRKDLVNSQADALASTANFLKNSGY
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QSGQPWGYEVRLPANINASNDRKNKQPISHWRNLGITLVDGSELSDSLSNAGLLLPAGKN
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHCCCCEEEECCCC
GPAFLVGRNFDAFYAYNASENYALAIAHLSDRIEQQNTDVDFATPWPTDDPGLSRKQSRE
CCEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
LQQALNLLGYDIGEVDGIIGDGTRRAIQQYQTDNGLTPDGRAGKKIHQHLMHVTANMPQH
HHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
ESEPADEAQHTADDDQLATGNAHSASKKISETKSGLSKLLQIKSLTAILIGLFIVLVIAL
CCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRRKR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]