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The map label for this gene is trpS [H]

Identifier: 148653750

GI number: 148653750

Start: 2435897

End: 2436994

Strand: Direct

Name: trpS [H]

Synonym: PsycPRwf_1953

Alternate gene names: 148653750

Gene position: 2435897-2436994 (Clockwise)

Preceding gene: 148653748

Following gene: 148653751

Centisome position: 81.77

GC content: 45.54

Gene sequence:

>1098_bases
ATGACTGTAGAACAAAATACTTCAGAGCACGCTCAAAAAGCCGAAGACACTCAGCCAAAACGTATCTTAACTGGTGTTAC
CACAACCGGTATCCCACACTTAGGTAACTATGTGGGTGCTATTCGTCCTGCGATTCAATCTGCGCAAAACAGCCTAAATG
AAGAAGATCAGTCTTTTTTCTTTTTGGCCGACTACCATGGCATTATCAAATGCTATGACCCAAAACAAATTCACGAATCA
ACCAAAGCCATTGCTGCCACTTGGCTTGCGTGTGGTCTTGACCCTGAAAAGGTAGTGTTTTATCGTCAATCTGATGTGCC
TGAGATTCCAGAGCTTGCGTGGATTTTAAACTGTTCATGTCCCAAAGGACTGATGAACCGAGCCCATGCTTATAAAGCGG
CGGTCGACATTAATAATGAAAAAAGTGACGTGGATCCCGACCAAGGTATCACCATGGGTCTGTTTGGGTATCCTGTATTA
ATGGCCGCTGACATCTTAATGTTTAATGCCACCCATGTGCCTGTCGGCCGTGACCAAATCCAGCACATTGAAATGGCGCG
CGATATCGCCGGTACGTTCAACCACAAATACAAGTCATTATTTACCCTACCCTCTGCGGTGGTAGATGAAAATGTGGCGC
TACTCACCGGTCTTGATGGTCGCAAGATGAGCAAAAGCTACGGCAATACCATTCCTTTATTTGGTGAATATAACCCACAA
GTAGACCCCGAAAAGCAGATGCGTAAGGCCATCATGCAAATTGTGACCAATTCACAGGCCCCTGAAGAGCCAAAAAATCC
TGATGACTCGGTAATCTTTGAGATCTATAAAGCCTTTGGTAGCACAGAAGAGATTGCAGATTTACGTGCTCAGTTTGAGG
CGGGGATTGCTTGGGGCGATGCTAAGCAGATTTTATTTGAAAAAATTAATAGTGAAATCGCCCCTTTCCGCGAGCGTTAT
TTTGAGCTGATGGCCAACCCTAAAGAGCTAGAGGAAATCTTGCTCATGGGGGCCGAAAAAGCCCGCCGTCACAGCCGCAA
ACAGTTGGATAAAACGCGCCGTGCTATCGGTATTAAGCCGTTAGCTAAGCTTAAATAA

Upstream 100 bases:

>100_bases
TAAGCAAATAAATCAGAATTTGTTATACTGCATTTACTTAAAATAGCTTCTTATATCTAAAGCCAGCCAAACCACTTCTC
TTTGTAAAAGTAGACCCCTT

Downstream 100 bases:

>100_bases
GGTTGGCATTTTTTGACAACTGTAAATGATAGCCGCTCAGACACGCAGGCCTATTCTGAGCCAAATTTAGACTCAGGCGC
TGGTATTAGAATCTATACCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTVEQNTSEHAQKAEDTQPKRILTGVTTTGIPHLGNYVGAIRPAIQSAQNSLNEEDQSFFFLADYHGIIKCYDPKQIHES
TKAIAATWLACGLDPEKVVFYRQSDVPEIPELAWILNCSCPKGLMNRAHAYKAAVDINNEKSDVDPDQGITMGLFGYPVL
MAADILMFNATHVPVGRDQIQHIEMARDIAGTFNHKYKSLFTLPSAVVDENVALLTGLDGRKMSKSYGNTIPLFGEYNPQ
VDPEKQMRKAIMQIVTNSQAPEEPKNPDDSVIFEIYKAFGSTEEIADLRAQFEAGIAWGDAKQILFEKINSEIAPFRERY
FELMANPKELEEILLMGAEKARRHSRKQLDKTRRAIGIKPLAKLK

Sequences:

>Translated_365_residues
MTVEQNTSEHAQKAEDTQPKRILTGVTTTGIPHLGNYVGAIRPAIQSAQNSLNEEDQSFFFLADYHGIIKCYDPKQIHES
TKAIAATWLACGLDPEKVVFYRQSDVPEIPELAWILNCSCPKGLMNRAHAYKAAVDINNEKSDVDPDQGITMGLFGYPVL
MAADILMFNATHVPVGRDQIQHIEMARDIAGTFNHKYKSLFTLPSAVVDENVALLTGLDGRKMSKSYGNTIPLFGEYNPQ
VDPEKQMRKAIMQIVTNSQAPEEPKNPDDSVIFEIYKAFGSTEEIADLRAQFEAGIAWGDAKQILFEKINSEIAPFRERY
FELMANPKELEEILLMGAEKARRHSRKQLDKTRRAIGIKPLAKLK
>Mature_364_residues
TVEQNTSEHAQKAEDTQPKRILTGVTTTGIPHLGNYVGAIRPAIQSAQNSLNEEDQSFFFLADYHGIIKCYDPKQIHEST
KAIAATWLACGLDPEKVVFYRQSDVPEIPELAWILNCSCPKGLMNRAHAYKAAVDINNEKSDVDPDQGITMGLFGYPVLM
AADILMFNATHVPVGRDQIQHIEMARDIAGTFNHKYKSLFTLPSAVVDENVALLTGLDGRKMSKSYGNTIPLFGEYNPQV
DPEKQMRKAIMQIVTNSQAPEEPKNPDDSVIFEIYKAFGSTEEIADLRAQFEAGIAWGDAKQILFEKINSEIAPFRERYF
ELMANPKELEEILLMGAEKARRHSRKQLDKTRRAIGIKPLAKLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=342, Percent_Identity=30.7017543859649, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI41352700, Length=193, Percent_Identity=39.3782383419689, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI1789786, Length=344, Percent_Identity=32.5581395348837, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=357, Percent_Identity=31.6526610644258, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71982793, Length=359, Percent_Identity=31.4763231197772, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=30.4597701149425, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24666151, Length=353, Percent_Identity=30.5949008498584, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 40898; Mature: 40767

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEQNTSEHAQKAEDTQPKRILTGVTTTGIPHLGNYVGAIRPAIQSAQNSLNEEDQSFF
CCCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FLADYHGIIKCYDPKQIHESTKAIAATWLACGLDPEKVVFYRQSDVPEIPELAWILNCSC
EEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCHHEEEEECCC
PKGLMNRAHAYKAAVDINNEKSDVDPDQGITMGLFGYPVLMAADILMFNATHVPVGRDQI
CHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QHIEMARDIAGTFNHKYKSLFTLPSAVVDENVALLTGLDGRKMSKSYGNTIPLFGEYNPQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCC
VDPEKQMRKAIMQIVTNSQAPEEPKNPDDSVIFEIYKAFGSTEEIADLRAQFEAGIAWGD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
AKQILFEKINSEIAPFRERYFELMANPKELEEILLMGAEKARRHSRKQLDKTRRAIGIKP
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
LAKLK
HHHCC
>Mature Secondary Structure 
TVEQNTSEHAQKAEDTQPKRILTGVTTTGIPHLGNYVGAIRPAIQSAQNSLNEEDQSFF
CCCCCCHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
FLADYHGIIKCYDPKQIHESTKAIAATWLACGLDPEKVVFYRQSDVPEIPELAWILNCSC
EEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCHHEEEEECCC
PKGLMNRAHAYKAAVDINNEKSDVDPDQGITMGLFGYPVLMAADILMFNATHVPVGRDQI
CHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QHIEMARDIAGTFNHKYKSLFTLPSAVVDENVALLTGLDGRKMSKSYGNTIPLFGEYNPQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCC
VDPEKQMRKAIMQIVTNSQAPEEPKNPDDSVIFEIYKAFGSTEEIADLRAQFEAGIAWGD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
AKQILFEKINSEIAPFRERYFELMANPKELEEILLMGAEKARRHSRKQLDKTRRAIGIKP
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
LAKLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]