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The map label for this gene is dinB [H]

Identifier: 148653720

GI number: 148653720

Start: 2389734

End: 2390843

Strand: Direct

Name: dinB [H]

Synonym: PsycPRwf_1923

Alternate gene names: 148653720

Gene position: 2389734-2390843 (Clockwise)

Preceding gene: 148653719

Following gene: 148653721

Centisome position: 80.22

GC content: 52.43

Gene sequence:

>1110_bases
ATGAGCCATTTAACTTCCTCTTCGCCTGAGCCCGCTGTGCAGCTACAGCGCAAGATTATCCATCTTGATATGGATGCGTT
TTATGCCAGTGTTGAGCAGCGGGATAACCCACAGCTGCGCGGAAAGCCGTTGGTGGTCGGTGGTGACCCCAGTGGCCGCG
GTGTGGTGGCCGCTGCCAGTTATGAGATACGCAAATTCGGGGTGCGCTCGGCCATGTCTTGCTATGAAGCTAAGCGGCGC
TGCCCTGAGGCCATATTCGTGCGTCCCCGCTTTGAGGTGTATCGTCAGGTCAGCCAACAGATCCGCGACATTATGCTCAG
CCTAACCGACTTGGTCGAGCCCTTATCGCTTGATGAAGCGTATCTTGATGTGACCGGGATTAAGGCGCATCACGGTTCGG
CGACCTTGATGGCCAATTGGCTGCGAGCACAGATTTATGAGCAGACCCAGCTGCGCGCTTCAGCCGGTGTGTCTTTTAAC
AAAATGCTCGCCAAGATTGCCTCGGATATTAATAAGCCCAATGGCATTGCGGTCATCACACCCGATCAGGCCGATGCCTT
TATTGCCACACTGCCGATTGAGCGGTTTCATGGTATCGGCAAAGCCACCGCCAAGCGCCTGCATGAAATGGGCATATATA
CCGGCGCTGATTTGCGCGCAGCGCCGGTGGACACTTTAGAGTATGAGTTTGGCAAGCGTGGCCGCTTTTATTCCGAGATT
GCTCACGGTAACGATAATCGACCTGTTAAAGCAGAACGCAAACACAAGTCAGTGGGCTCAGAGACCACCTTTCGCGATAA
CCTACGTGACACAGACAACTTACTGGTACAAATCTTTGAACAAAATGCCGATGCCTTTGAGCAACTGTCCAAAAAGGGAC
GTCTGGGCCACACCATTACCCTTAAGATAAAGTATGCTGACTTCACTCAAATCACCCGCTCACACACCTTGAACACGCCG
TTCCCTTCTGCTGAGTCGGCGCATTATTGGTTACAAAAGCTGTTCGCTGATGTCCCACGCCATCTGCCCATTCGCTTGGT
CGGGGTCACCTACTCAAACCTCACAAGCTTAGATGACTTAAACACGCAGCCTGATCTGTTTGGTTTATAA

Upstream 100 bases:

>100_bases
ACTAAGCGTGATTAATCTCTCCCAGAGCAGATCTCACTATATGGCGGCCTTTACTATGGGTTAGGATTATCAAGCAAAGA
TAATCCTATATAATAAGGTC

Downstream 100 bases:

>100_bases
CAAAGGCTCTTTAGTCCATAAAATCCCCTGTTAGGCACTCAATAGCAACTTAACTGACCCAAAACTCAACTCAAAAAACA
GTTATTTCTGTTAAACTACT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSHLTSSSPEPAVQLQRKIIHLDMDAFYASVEQRDNPQLRGKPLVVGGDPSGRGVVAAASYEIRKFGVRSAMSCYEAKRR
CPEAIFVRPRFEVYRQVSQQIRDIMLSLTDLVEPLSLDEAYLDVTGIKAHHGSATLMANWLRAQIYEQTQLRASAGVSFN
KMLAKIASDINKPNGIAVITPDQADAFIATLPIERFHGIGKATAKRLHEMGIYTGADLRAAPVDTLEYEFGKRGRFYSEI
AHGNDNRPVKAERKHKSVGSETTFRDNLRDTDNLLVQIFEQNADAFEQLSKKGRLGHTITLKIKYADFTQITRSHTLNTP
FPSAESAHYWLQKLFADVPRHLPIRLVGVTYSNLTSLDDLNTQPDLFGL

Sequences:

>Translated_369_residues
MSHLTSSSPEPAVQLQRKIIHLDMDAFYASVEQRDNPQLRGKPLVVGGDPSGRGVVAAASYEIRKFGVRSAMSCYEAKRR
CPEAIFVRPRFEVYRQVSQQIRDIMLSLTDLVEPLSLDEAYLDVTGIKAHHGSATLMANWLRAQIYEQTQLRASAGVSFN
KMLAKIASDINKPNGIAVITPDQADAFIATLPIERFHGIGKATAKRLHEMGIYTGADLRAAPVDTLEYEFGKRGRFYSEI
AHGNDNRPVKAERKHKSVGSETTFRDNLRDTDNLLVQIFEQNADAFEQLSKKGRLGHTITLKIKYADFTQITRSHTLNTP
FPSAESAHYWLQKLFADVPRHLPIRLVGVTYSNLTSLDDLNTQPDLFGL
>Mature_368_residues
SHLTSSSPEPAVQLQRKIIHLDMDAFYASVEQRDNPQLRGKPLVVGGDPSGRGVVAAASYEIRKFGVRSAMSCYEAKRRC
PEAIFVRPRFEVYRQVSQQIRDIMLSLTDLVEPLSLDEAYLDVTGIKAHHGSATLMANWLRAQIYEQTQLRASAGVSFNK
MLAKIASDINKPNGIAVITPDQADAFIATLPIERFHGIGKATAKRLHEMGIYTGADLRAAPVDTLEYEFGKRGRFYSEIA
HGNDNRPVKAERKHKSVGSETTFRDNLRDTDNLLVQIFEQNADAFEQLSKKGRLGHTITLKIKYADFTQITRSHTLNTPF
PSAESAHYWLQKLFADVPRHLPIRLVGVTYSNLTSLDDLNTQPDLFGL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=344, Percent_Identity=28.7790697674419, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI7706681, Length=345, Percent_Identity=28.695652173913, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI154350220, Length=397, Percent_Identity=28.463476070529, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI7705344, Length=116, Percent_Identity=44.8275862068966, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI5729982, Length=117, Percent_Identity=39.3162393162393, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786425, Length=303, Percent_Identity=45.2145214521452, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1787432, Length=206, Percent_Identity=31.0679611650485, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=415, Percent_Identity=27.9518072289157, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17537959, Length=373, Percent_Identity=26.2734584450402, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=225, Percent_Identity=31.5555555555556, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=36.8, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19923006, Length=343, Percent_Identity=26.530612244898, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355641, Length=343, Percent_Identity=29.4460641399417, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24644984, Length=343, Percent_Identity=29.4460641399417, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24668444, Length=136, Percent_Identity=33.8235294117647, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41312; Mature: 41181

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLTSSSPEPAVQLQRKIIHLDMDAFYASVEQRDNPQLRGKPLVVGGDPSGRGVVAAAS
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECC
YEIRKFGVRSAMSCYEAKRRCPEAIFVRPRFEVYRQVSQQIRDIMLSLTDLVEPLSLDEA
HHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
YLDVTGIKAHHGSATLMANWLRAQIYEQTQLRASAGVSFNKMLAKIASDINKPNGIAVIT
HEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEE
PDQADAFIATLPIERFHGIGKATAKRLHEMGIYTGADLRAAPVDTLEYEFGKRGRFYSEI
CCCCCCEEEECCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHH
AHGNDNRPVKAERKHKSVGSETTFRDNLRDTDNLLVQIFEQNADAFEQLSKKGRLGHTIT
HCCCCCCCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEE
LKIKYADFTQITRSHTLNTPFPSAESAHYWLQKLFADVPRHLPIRLVGVTYSNLTSLDDL
EEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCHHCC
NTQPDLFGL
CCCCCCCCC
>Mature Secondary Structure 
SHLTSSSPEPAVQLQRKIIHLDMDAFYASVEQRDNPQLRGKPLVVGGDPSGRGVVAAAS
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECC
YEIRKFGVRSAMSCYEAKRRCPEAIFVRPRFEVYRQVSQQIRDIMLSLTDLVEPLSLDEA
HHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
YLDVTGIKAHHGSATLMANWLRAQIYEQTQLRASAGVSFNKMLAKIASDINKPNGIAVIT
HEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEE
PDQADAFIATLPIERFHGIGKATAKRLHEMGIYTGADLRAAPVDTLEYEFGKRGRFYSEI
CCCCCCEEEECCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHH
AHGNDNRPVKAERKHKSVGSETTFRDNLRDTDNLLVQIFEQNADAFEQLSKKGRLGHTIT
HCCCCCCCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEE
LKIKYADFTQITRSHTLNTPFPSAESAHYWLQKLFADVPRHLPIRLVGVTYSNLTSLDDL
EEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCHHCC
NTQPDLFGL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA