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The map label for this gene is glnG [H]

Identifier: 148653602

GI number: 148653602

Start: 2239205

End: 2241013

Strand: Direct

Name: glnG [H]

Synonym: PsycPRwf_1805

Alternate gene names: 148653602

Gene position: 2239205-2241013 (Clockwise)

Preceding gene: 148653601

Following gene: 148653604

Centisome position: 75.17

GC content: 49.47

Gene sequence:

>1809_bases
ATGGAAACTCAGACAATGACAACAAAACACAGCTTATGGTTAATCGATGATGATCCTGCTTTAAGACTTATTTTAGAGGA
CTCCTTTAGTGATGCCGGCTTGCAAGTGCAAGCTTTTAGCAATGCCAAAGGGGCCTGGGCTAGGTTAAATAGTGTATTAA
ATGGCAGTGAGCCAGAAGACATATTGCCTGATGTGATACTAACTGACATTCGCATGCCGATGATGGATGGGCTGTCTTTT
AGTCAGTGGATGCACACCAACTTCCCCAGCCTACCTGTCATTATCATGACGGCTCACTCAGACTTAAAATCCGCAGTTGA
CAGCTATGACACCGGTGCTTTTGAATATCTGCCCAAGCCTTTTGATTTAGATCATGCAATCTGTGTGGTTAAAAAAGCCA
TTACCACCAATCCGGCAGCGGCCTTAGTAGACAACGCCATAGTGGCAGAAGACTCAGAGGTGCCAAGTGCTGCTTCAGAT
AAAAAAGAGGCTATGCAGCGCCCTAATACCACGCCGTCATCAGAGATAAAAAAACAACCTGCTACCAAAAAAGGCTCCCC
TGTAGCGACTAAAGCCTCAGCGGCAAGCGAATCTACCCCTATCATCGGTCAATCCCCAGCAATGCAAACTGTGTTTCGTG
CCATTGGCCGCTTGGCCTCCTCGCCGATTACTGTCTTAATCACCGGGGAGTCAGGCACGGGCAAGGAGCTGGTGGCCGGT
GCGCTGCATCAAAACTCACCGCGTCAAAAAAAGCCCTTTATTGCGCTTAATATGGCCGCTATTCCGCACGAGTTAATAGA
ATCTGAGCTGTTCGGTCATGAAAAAGGGGCATTTACCGGAGCCACCACCTTGCGACATGGCCGCTTTGAGCAGGCCAATG
GTGGGACACTGTTTTTGGACGAAATCGGTGACATGCCTTTTAGCACCCAGACTCGGCTGCTGCGGGTCTTGGCCAATGGT
GAATTCTTTCGAGTGGGCGGTCAAAAGCCAATTACTGTCGATGTGCGCATCATTGCCGCCACCCACCAAAACCTTGAACA
ATTGGTGAAAGAAGGCAAGTTTCGTGAAGATTTATTTTATCGCTTAAATGTCATTCGACTGCCGCTACCGCCGCTACGAG
CGCGCCCCGATGACATACCTGATTTGGTTGAGTTCTTTATGAGCAAAGCGGCCACTGAGATGAAAACCGATAAAAAACAG
CTGACTACAGAGGCACTACATATTATGCAAGCCTTTGATTGGCCAGGAAATGTACGTCAACTTGAAAATGCTTGCCGCTG
GATTACCGTGATGGCCACAGGAGAGAGGCTCGGTGTGGAGGATTTGCCTCCTGATTTAACCGAGTTTGCACAGCATTATC
TGGCTCATGCCGCAAACCCTGAAGCACTAGAGGGTCAAGGTATGCAAACTCTCAGCAACCTGCCAAATAATAGCCCAGGT
TTTGCCGCACCCAGCACCACTGCATCTGCGGCGTCTTATACACAAGGCAATTCTCCAAGCTTTGCGGCAACCGCTCAGTC
TGATGAGCACCGACAAACCAGCACCGCTTCAGTCACCATCACACCGCCCGCCTTAGTGAACAGCGCCCATAGCTGGCAAG
ATCAGCTACAAAATTGGGCCCATACCGCTTTGCAGCAAGGACAAACCGAAATTTTGCAGCAGGCCACTCCCACATTTGAA
AAAATCTTGATTCGCGTGGCGCTTGAATACAGCAAAGGTCGAAAAGGTGAAGCTGCTGACCTACTCGGCTGGGGGCGCAA
TACCTTAACTCGCAAGATAAAGCTGCTTGGGCTAGAAGGCGATCAATAG

Upstream 100 bases:

>100_bases
GCTCACTGATGAGCTGGACTCAAAGCTGCAAATAGAGGATGCCCCCTGCCCCTTAGTTATCCTCTGCAAACTGCCAATTA
CTTGCTAAATATTCACGACA

Downstream 100 bases:

>100_bases
AGCGTTTATTGAAAGCCAAAATCGCATAAACGCTATAAAAACTAACGCTGTTTTGCGATTTAACCTTAAAAAACGTCGAA
AAATTAAAAAAAATACTTGC

Product: nitrogen metabolism transcriptional regulator NtrC

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
METQTMTTKHSLWLIDDDPALRLILEDSFSDAGLQVQAFSNAKGAWARLNSVLNGSEPEDILPDVILTDIRMPMMDGLSF
SQWMHTNFPSLPVIIMTAHSDLKSAVDSYDTGAFEYLPKPFDLDHAICVVKKAITTNPAAALVDNAIVAEDSEVPSAASD
KKEAMQRPNTTPSSEIKKQPATKKGSPVATKASAASESTPIIGQSPAMQTVFRAIGRLASSPITVLITGESGTGKELVAG
ALHQNSPRQKKPFIALNMAAIPHELIESELFGHEKGAFTGATTLRHGRFEQANGGTLFLDEIGDMPFSTQTRLLRVLANG
EFFRVGGQKPITVDVRIIAATHQNLEQLVKEGKFREDLFYRLNVIRLPLPPLRARPDDIPDLVEFFMSKAATEMKTDKKQ
LTTEALHIMQAFDWPGNVRQLENACRWITVMATGERLGVEDLPPDLTEFAQHYLAHAANPEALEGQGMQTLSNLPNNSPG
FAAPSTTASAASYTQGNSPSFAATAQSDEHRQTSTASVTITPPALVNSAHSWQDQLQNWAHTALQQGQTEILQQATPTFE
KILIRVALEYSKGRKGEAADLLGWGRNTLTRKIKLLGLEGDQ

Sequences:

>Translated_602_residues
METQTMTTKHSLWLIDDDPALRLILEDSFSDAGLQVQAFSNAKGAWARLNSVLNGSEPEDILPDVILTDIRMPMMDGLSF
SQWMHTNFPSLPVIIMTAHSDLKSAVDSYDTGAFEYLPKPFDLDHAICVVKKAITTNPAAALVDNAIVAEDSEVPSAASD
KKEAMQRPNTTPSSEIKKQPATKKGSPVATKASAASESTPIIGQSPAMQTVFRAIGRLASSPITVLITGESGTGKELVAG
ALHQNSPRQKKPFIALNMAAIPHELIESELFGHEKGAFTGATTLRHGRFEQANGGTLFLDEIGDMPFSTQTRLLRVLANG
EFFRVGGQKPITVDVRIIAATHQNLEQLVKEGKFREDLFYRLNVIRLPLPPLRARPDDIPDLVEFFMSKAATEMKTDKKQ
LTTEALHIMQAFDWPGNVRQLENACRWITVMATGERLGVEDLPPDLTEFAQHYLAHAANPEALEGQGMQTLSNLPNNSPG
FAAPSTTASAASYTQGNSPSFAATAQSDEHRQTSTASVTITPPALVNSAHSWQDQLQNWAHTALQQGQTEILQQATPTFE
KILIRVALEYSKGRKGEAADLLGWGRNTLTRKIKLLGLEGDQ
>Mature_602_residues
METQTMTTKHSLWLIDDDPALRLILEDSFSDAGLQVQAFSNAKGAWARLNSVLNGSEPEDILPDVILTDIRMPMMDGLSF
SQWMHTNFPSLPVIIMTAHSDLKSAVDSYDTGAFEYLPKPFDLDHAICVVKKAITTNPAAALVDNAIVAEDSEVPSAASD
KKEAMQRPNTTPSSEIKKQPATKKGSPVATKASAASESTPIIGQSPAMQTVFRAIGRLASSPITVLITGESGTGKELVAG
ALHQNSPRQKKPFIALNMAAIPHELIESELFGHEKGAFTGATTLRHGRFEQANGGTLFLDEIGDMPFSTQTRLLRVLANG
EFFRVGGQKPITVDVRIIAATHQNLEQLVKEGKFREDLFYRLNVIRLPLPPLRARPDDIPDLVEFFMSKAATEMKTDKKQ
LTTEALHIMQAFDWPGNVRQLENACRWITVMATGERLGVEDLPPDLTEFAQHYLAHAANPEALEGQGMQTLSNLPNNSPG
FAAPSTTASAASYTQGNSPSFAATAQSDEHRQTSTASVTITPPALVNSAHSWQDQLQNWAHTALQQGQTEILQQATPTFE
KILIRVALEYSKGRKGEAADLLGWGRNTLTRKIKLLGLEGDQ

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=588, Percent_Identity=47.2789115646259, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788550, Length=443, Percent_Identity=41.0835214446953, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1790437, Length=432, Percent_Identity=38.8888888888889, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI87082117, Length=302, Percent_Identity=47.3509933774834, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1788905, Length=423, Percent_Identity=37.3522458628842, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1789233, Length=248, Percent_Identity=49.1935483870968, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789087, Length=242, Percent_Identity=48.7603305785124, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082152, Length=259, Percent_Identity=45.945945945946, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786524, Length=276, Percent_Identity=46.7391304347826, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1787583, Length=255, Percent_Identity=46.2745098039216, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI87081872, Length=246, Percent_Identity=44.3089430894309, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789828, Length=273, Percent_Identity=32.967032967033, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081858, Length=233, Percent_Identity=33.0472103004292, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65622; Mature: 65622

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQTMTTKHSLWLIDDDPALRLILEDSFSDAGLQVQAFSNAKGAWARLNSVLNGSEPED
CCCCCEEEECEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHH
ILPDVILTDIRMPMMDGLSFSQWMHTNFPSLPVIIMTAHSDLKSAVDSYDTGAFEYLPKP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCC
FDLDHAICVVKKAITTNPAAALVDNAIVAEDSEVPSAASDKKEAMQRPNTTPSSEIKKQP
CCCCHHHHHHHHHHCCCCHHHHHCCHHEECCCCCCCCCCHHHHHHHCCCCCCHHHHHCCC
ATKKGSPVATKASAASESTPIIGQSPAMQTVFRAIGRLASSPITVLITGESGTGKELVAG
CCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
ALHQNSPRQKKPFIALNMAAIPHELIESELFGHEKGAFTGATTLRHGRFEQANGGTLFLD
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEH
EIGDMPFSTQTRLLRVLANGEFFRVGGQKPITVDVRIIAATHQNLEQLVKEGKFREDLFY
HHCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEHHHHHHHHHHHCCCHHHHHHH
RLNVIRLPLPPLRARPDDIPDLVEFFMSKAATEMKTDKKQLTTEALHIMQAFDWPGNVRQ
HEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LENACRWITVMATGERLGVEDLPPDLTEFAQHYLAHAANPEALEGQGMQTLSNLPNNSPG
HHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC
FAAPSTTASAASYTQGNSPSFAATAQSDEHRQTSTASVTITPPALVNSAHSWQDQLQNWA
CCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHH
HTALQQGQTEILQQATPTFEKILIRVALEYSKGRKGEAADLLGWGRNTLTRKIKLLGLEG
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHEEEEEEEECCC
DQ
CC
>Mature Secondary Structure
METQTMTTKHSLWLIDDDPALRLILEDSFSDAGLQVQAFSNAKGAWARLNSVLNGSEPED
CCCCCEEEECEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHH
ILPDVILTDIRMPMMDGLSFSQWMHTNFPSLPVIIMTAHSDLKSAVDSYDTGAFEYLPKP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCC
FDLDHAICVVKKAITTNPAAALVDNAIVAEDSEVPSAASDKKEAMQRPNTTPSSEIKKQP
CCCCHHHHHHHHHHCCCCHHHHHCCHHEECCCCCCCCCCHHHHHHHCCCCCCHHHHHCCC
ATKKGSPVATKASAASESTPIIGQSPAMQTVFRAIGRLASSPITVLITGESGTGKELVAG
CCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
ALHQNSPRQKKPFIALNMAAIPHELIESELFGHEKGAFTGATTLRHGRFEQANGGTLFLD
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEH
EIGDMPFSTQTRLLRVLANGEFFRVGGQKPITVDVRIIAATHQNLEQLVKEGKFREDLFY
HHCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEHHHHHHHHHHHCCCHHHHHHH
RLNVIRLPLPPLRARPDDIPDLVEFFMSKAATEMKTDKKQLTTEALHIMQAFDWPGNVRQ
HEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LENACRWITVMATGERLGVEDLPPDLTEFAQHYLAHAANPEALEGQGMQTLSNLPNNSPG
HHHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCC
FAAPSTTASAASYTQGNSPSFAATAQSDEHRQTSTASVTITPPALVNSAHSWQDQLQNWA
CCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHH
HTALQQGQTEILQQATPTFEKILIRVALEYSKGRKGEAADLLGWGRNTLTRKIKLLGLEG
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHEEEEEEEECCC
DQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]