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The map label for this gene is mrdB [H]

Identifier: 148653583

GI number: 148653583

Start: 2214236

End: 2215378

Strand: Direct

Name: mrdB [H]

Synonym: PsycPRwf_1786

Alternate gene names: 148653583

Gene position: 2214236-2215378 (Clockwise)

Preceding gene: 148653580

Following gene: 148653584

Centisome position: 74.33

GC content: 48.38

Gene sequence:

>1143_bases
ATGTCAAAGAACCAACAATATCGATTTTCTCGGCAAACACATCATTTTGGCCGAGATGACAACATTAGTATCTGGCAACG
CATACACATTGACCCTTGGTTGATGTTGCTGCTTTTGACCGTCTGTTTTATTGGTCTGGCCATTTTATACAGTGCTTCAA
CCCAAGATGTGGCGATGGTAACCCGTCAGATGGTCAGCTATCTAATCGCTTTTTCGGTGATGATAGGTATGGCGCAGATA
CCGCCTGGGATGTATCGTGATTTCACGCCGTTTTTTTATGTGATAGGCCTGTTCTCTTTGATATTGGTCGACCTCATCGG
CGAGGTGCGTATGGGTGCTCAGCGCTGGATTGCCATTCCTGGTTTCGGTAGCGTGCAGCCTTCAGAGTTTATGAAGCTTG
GCTTACCTATGATGTGTGCTTGGTATCTGTCACGCCGCGATTTGCCGCCCAACTTGATAACAGTGGCCTCGACATTGGCC
ATTATTGTTGTGCCAGTATTACTCATTGCTAAAGAGCCAGATTTGGGCACCTCGCTATTGGTTGCTGCCAGTGGCTTTTT
TGTGCTGTTTTTAGCCGGCCTACCTTGGTGGATGATTGGTTCAGCCATTGGTTTGATGATTCCGCTGGTCTGGGCCGGTT
GGATGTTCTTTATGCACGACTATCAAAAACAGCGGGTATTGACCCTGTTAAACCCCGAGGCGGATATGCTGGGTGCGGGA
TGGAACATCACCCAGTCTAAGACAGCCATCGGTGCTGGCGGGCTGACAGGTAAAGGCTATCTAGAGGGGACTCAATCACA
TCTGCACTTTTTGCCGGAAGGACACACTGATTTTATTATTGCTGCTTTCTCAGAAGAGTTTGGGCTGCTTGGCGTCAGCG
TGCTGATGTTTTTATATGCCTGTATTTTGGTGCGCTCACTGTTTATCGCCTCTGTGCATGTCGATACTTACGGCAGACTG
CTTGCCGGCGCCATTGGTATGTCATTTTTTGTGTATGTGTTCGTCAATATTGGTATGGTGGGCGGTATCTTGCCAATCGT
TGGGGTACCGCTGCCGCTGATCAGTTACGGCGGCACGGCCATTATTACCTTGATGGCAGGTTTCGGTCTGTTAATGTCGG
TATATACCCACAATACCAAGTAA

Upstream 100 bases:

>100_bases
ACGCAGCAACACTAGATAATTGATGGCTTAATTGAGTGGTTCAACTCAATATCGCTACGATGCACGCCCCCTTTACTAAC
TTCAGTAAAAAAACCGCCCT

Downstream 100 bases:

>100_bases
TTAAAATGGCTTATTTTTGGGCGCTGATGCAAAGGTCTATAACGACACTAGCTGTCGTATAAAACTGCGTTTTGGCCGAT
AATCCCTTAAGTCTCTGGTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSKNQQYRFSRQTHHFGRDDNISIWQRIHIDPWLMLLLLTVCFIGLAILYSASTQDVAMVTRQMVSYLIAFSVMIGMAQI
PPGMYRDFTPFFYVIGLFSLILVDLIGEVRMGAQRWIAIPGFGSVQPSEFMKLGLPMMCAWYLSRRDLPPNLITVASTLA
IIVVPVLLIAKEPDLGTSLLVAASGFFVLFLAGLPWWMIGSAIGLMIPLVWAGWMFFMHDYQKQRVLTLLNPEADMLGAG
WNITQSKTAIGAGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVSVLMFLYACILVRSLFIASVHVDTYGRL
LAGAIGMSFFVYVFVNIGMVGGILPIVGVPLPLISYGGTAIITLMAGFGLLMSVYTHNTK

Sequences:

>Translated_380_residues
MSKNQQYRFSRQTHHFGRDDNISIWQRIHIDPWLMLLLLTVCFIGLAILYSASTQDVAMVTRQMVSYLIAFSVMIGMAQI
PPGMYRDFTPFFYVIGLFSLILVDLIGEVRMGAQRWIAIPGFGSVQPSEFMKLGLPMMCAWYLSRRDLPPNLITVASTLA
IIVVPVLLIAKEPDLGTSLLVAASGFFVLFLAGLPWWMIGSAIGLMIPLVWAGWMFFMHDYQKQRVLTLLNPEADMLGAG
WNITQSKTAIGAGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVSVLMFLYACILVRSLFIASVHVDTYGRL
LAGAIGMSFFVYVFVNIGMVGGILPIVGVPLPLISYGGTAIITLMAGFGLLMSVYTHNTK
>Mature_379_residues
SKNQQYRFSRQTHHFGRDDNISIWQRIHIDPWLMLLLLTVCFIGLAILYSASTQDVAMVTRQMVSYLIAFSVMIGMAQIP
PGMYRDFTPFFYVIGLFSLILVDLIGEVRMGAQRWIAIPGFGSVQPSEFMKLGLPMMCAWYLSRRDLPPNLITVASTLAI
IVVPVLLIAKEPDLGTSLLVAASGFFVLFLAGLPWWMIGSAIGLMIPLVWAGWMFFMHDYQKQRVLTLLNPEADMLGAGW
NITQSKTAIGAGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVSVLMFLYACILVRSLFIASVHVDTYGRLL
AGAIGMSFFVYVFVNIGMVGGILPIVGVPLPLISYGGTAIITLMAGFGLLMSVYTHNTK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=49.7222222222222, Blast_Score=340, Evalue=7e-95,
Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=31.9444444444444, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41898; Mature: 41766

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNQQYRFSRQTHHFGRDDNISIWQRIHIDPWLMLLLLTVCFIGLAILYSASTQDVAMV
CCCCCCCHHHHHHHCCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TRQMVSYLIAFSVMIGMAQIPPGMYRDFTPFFYVIGLFSLILVDLIGEVRMGAQRWIAIP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECC
GFGSVQPSEFMKLGLPMMCAWYLSRRDLPPNLITVASTLAIIVVPVLLIAKEPDLGTSLL
CCCCCCHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VAASGFFVLFLAGLPWWMIGSAIGLMIPLVWAGWMFFMHDYQKQRVLTLLNPEADMLGAG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCC
WNITQSKTAIGAGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVSVLMFLYA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEEECHHHHHHHHHHHHHHHH
CILVRSLFIASVHVDTYGRLLAGAIGMSFFVYVFVNIGMVGGILPIVGVPLPLISYGGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHH
IITLMAGFGLLMSVYTHNTK
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKNQQYRFSRQTHHFGRDDNISIWQRIHIDPWLMLLLLTVCFIGLAILYSASTQDVAMV
CCCCCCHHHHHHHCCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TRQMVSYLIAFSVMIGMAQIPPGMYRDFTPFFYVIGLFSLILVDLIGEVRMGAQRWIAIP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECC
GFGSVQPSEFMKLGLPMMCAWYLSRRDLPPNLITVASTLAIIVVPVLLIAKEPDLGTSLL
CCCCCCHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VAASGFFVLFLAGLPWWMIGSAIGLMIPLVWAGWMFFMHDYQKQRVLTLLNPEADMLGAG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCC
WNITQSKTAIGAGGLTGKGYLEGTQSHLHFLPEGHTDFIIAAFSEEFGLLGVSVLMFLYA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEEECHHHHHHHHHHHHHHHH
CILVRSLFIASVHVDTYGRLLAGAIGMSFFVYVFVNIGMVGGILPIVGVPLPLISYGGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHH
IITLMAGFGLLMSVYTHNTK
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]