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The map label for this gene is pqqL [C]

Identifier: 148653579

GI number: 148653579

Start: 2208729

End: 2210321

Strand: Direct

Name: pqqL [C]

Synonym: PsycPRwf_1782

Alternate gene names: 148653579

Gene position: 2208729-2210321 (Clockwise)

Preceding gene: 148653573

Following gene: 148653580

Centisome position: 74.14

GC content: 47.52

Gene sequence:

>1593_bases
ATGAAAACTGATTTTTTAACCCATTGCCCAGCAACCGGCCATCACACTTCATCAAATTCACACCCAACCCTTGCCTCATT
ACCCCAAGCCTCACCTCATGCGGGTATCAAGCGCCTCAAGCTGAGCGTATTGGCGGCAATGACCGTCACAGCGCTGGCCG
CTTGCAGTAGCTTACCGGCAGCCCAAAGTGACACAGATAACAAGGCTGCCCGTCCCGCTGTATCCTCAGCGGACACACAC
TTTGCTGATGATGATAGCCGTCATGAATATCAACTAGATAATGGGTTAAAAGTCATCATTAAAGAGGACCACAGAGCGCC
GGTTGCCATGACTCAAATTTGGTATGGTGTGGGGTCAACCGATGAGCCTAAGGACAAAGGCGGTATCTCACATCTGCTTG
AACACATGATGTTTAAAGGTACCAAAAAAGTCTCAGGTGCCGACTTTGATCGCTTAATTGCCAAGTTTGGCGGCGATCAT
AATGCCTTTACCAGCTATGACTACACCGGCTACTATGAGATGTTTCCAGTAAATCGCCTTGATTTGGCATTAGAGCTTGA
GTCTGATCGTATGGTGAATCTGCGCTTTGACAGTGATGAATTTGTCCAAGAATTTGCCCAAGAGCGCAACGTGGTGATGG
AGGAGCGCCGCCAACGTACCGATGACAATCCTTTGGCGCGCGCCTTTGAAAAGTTTCGCAAAATGGCCCTGCCTGATAGC
CCCAAAGGCGAGTCCGTCATTGGCCCGATGGATGAGATTGCCAATACCGATATCAAAGACTTACAACAGTGGTATGACAC
CTGGTATGCCCCAAACAACGCCACCTTGGTTATCGTGGGTGATGTCAATCCTAAAGAGACCCTAAAAAAAGTTGAGCATT
ATTTTGGGTCGATCAAGCACAAACCCATTCCTCAGCGTCCCTCAGTACAGCAGCAAGCTTTTCGCGGATATCAGCAGCAG
ACTGTAAAAGAAACGGTCAATGTTCCCACCTTAATTATGGCATTTAATGTGCCCACTCTGCCCAGCGCCATAACCGCTAA
CAGCTCTGATAAAGAGGTCTATGAGCTGTTAATGCTGCAATATATTATGGATGGCGGCTATGCTGCACGCTTCGAAAAAA
ACTTAGTGCGCAAGCAAGGTTTACTGGCCTCAGTGGTGGCTTATTATGATGCTTATGAACGGGGTGATGGGCTGTTTATG
GTGCAAGCCACTCCTCGTGAGGGAGTAAGCTTGGCTCAAGCACAAAAAGCAATTATAGATGAGATGGATACATTAAAAAC
CCAGACCATCAGCAAGCAAGAGCTTGAGCGGGCACGCAACAACGCAATAAATGGCTTTGTGTTCTCGCAAGACAGTATGG
CCGGTCAAGCCAATATGATAGGCAGCTTACAAGTACGCGGTTTGGATGATCGTTTGGTCACCACTTTACCTGATAAGTTG
GCCAAAGTAACCAGCGCAGATGTCAATGCAGCTGCAAGCAAATATTTAGTTAATAATAACTTAAATGTGATGTATGTAGA
GCCTGCTGAGACACGTAGCGTCATGCCTGCCTCTAATTCTATGCCAGCTCAGCCCATGCCAGCTAAACCATAA

Upstream 100 bases:

>100_bases
GCTATAATAATTAAAATCAACCCCATACTAATGATTTTATTGCTCTATTGAACAGCCTATAGGTTATAACACCTTTTTAA
ACCGATAACTTGAGGACTGC

Downstream 100 bases:

>100_bases
AACCGCTAATTATGCGCCAATAAACGCCAGACCAATTGCCATTGACCACCAATAAAACACCCTTTTTAAAAATATAAAAC
CTAATTACGGATTTTGTTAT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MKTDFLTHCPATGHHTSSNSHPTLASLPQASPHAGIKRLKLSVLAAMTVTALAACSSLPAAQSDTDNKAARPAVSSADTH
FADDDSRHEYQLDNGLKVIIKEDHRAPVAMTQIWYGVGSTDEPKDKGGISHLLEHMMFKGTKKVSGADFDRLIAKFGGDH
NAFTSYDYTGYYEMFPVNRLDLALELESDRMVNLRFDSDEFVQEFAQERNVVMEERRQRTDDNPLARAFEKFRKMALPDS
PKGESVIGPMDEIANTDIKDLQQWYDTWYAPNNATLVIVGDVNPKETLKKVEHYFGSIKHKPIPQRPSVQQQAFRGYQQQ
TVKETVNVPTLIMAFNVPTLPSAITANSSDKEVYELLMLQYIMDGGYAARFEKNLVRKQGLLASVVAYYDAYERGDGLFM
VQATPREGVSLAQAQKAIIDEMDTLKTQTISKQELERARNNAINGFVFSQDSMAGQANMIGSLQVRGLDDRLVTTLPDKL
AKVTSADVNAAASKYLVNNNLNVMYVEPAETRSVMPASNSMPAQPMPAKP

Sequences:

>Translated_530_residues
MKTDFLTHCPATGHHTSSNSHPTLASLPQASPHAGIKRLKLSVLAAMTVTALAACSSLPAAQSDTDNKAARPAVSSADTH
FADDDSRHEYQLDNGLKVIIKEDHRAPVAMTQIWYGVGSTDEPKDKGGISHLLEHMMFKGTKKVSGADFDRLIAKFGGDH
NAFTSYDYTGYYEMFPVNRLDLALELESDRMVNLRFDSDEFVQEFAQERNVVMEERRQRTDDNPLARAFEKFRKMALPDS
PKGESVIGPMDEIANTDIKDLQQWYDTWYAPNNATLVIVGDVNPKETLKKVEHYFGSIKHKPIPQRPSVQQQAFRGYQQQ
TVKETVNVPTLIMAFNVPTLPSAITANSSDKEVYELLMLQYIMDGGYAARFEKNLVRKQGLLASVVAYYDAYERGDGLFM
VQATPREGVSLAQAQKAIIDEMDTLKTQTISKQELERARNNAINGFVFSQDSMAGQANMIGSLQVRGLDDRLVTTLPDKL
AKVTSADVNAAASKYLVNNNLNVMYVEPAETRSVMPASNSMPAQPMPAKP
>Mature_530_residues
MKTDFLTHCPATGHHTSSNSHPTLASLPQASPHAGIKRLKLSVLAAMTVTALAACSSLPAAQSDTDNKAARPAVSSADTH
FADDDSRHEYQLDNGLKVIIKEDHRAPVAMTQIWYGVGSTDEPKDKGGISHLLEHMMFKGTKKVSGADFDRLIAKFGGDH
NAFTSYDYTGYYEMFPVNRLDLALELESDRMVNLRFDSDEFVQEFAQERNVVMEERRQRTDDNPLARAFEKFRKMALPDS
PKGESVIGPMDEIANTDIKDLQQWYDTWYAPNNATLVIVGDVNPKETLKKVEHYFGSIKHKPIPQRPSVQQQAFRGYQQQ
TVKETVNVPTLIMAFNVPTLPSAITANSSDKEVYELLMLQYIMDGGYAARFEKNLVRKQGLLASVVAYYDAYERGDGLFM
VQATPREGVSLAQAQKAIIDEMDTLKTQTISKQELERARNNAINGFVFSQDSMAGQANMIGSLQVRGLDDRLVTTLPDKL
AKVTSADVNAAASKYLVNNNLNVMYVEPAETRSVMPASNSMPAQPMPAKP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=434, Percent_Identity=25.3456221198157, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI46593007, Length=207, Percent_Identity=27.536231884058, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI155969707, Length=310, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787770, Length=208, Percent_Identity=34.1346153846154, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI2367164, Length=379, Percent_Identity=24.802110817942, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=209, Percent_Identity=28.2296650717703, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17553678, Length=294, Percent_Identity=25.8503401360544, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994338, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146563, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=225, Percent_Identity=28.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=225, Percent_Identity=28.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533970, Length=223, Percent_Identity=29.1479820627803, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72001443, Length=236, Percent_Identity=26.6949152542373, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=216, Percent_Identity=25.462962962963, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357875, Length=214, Percent_Identity=29.4392523364486, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646943, Length=214, Percent_Identity=29.4392523364486, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221513245, Length=272, Percent_Identity=25.7352941176471, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 58796; Mature: 58796

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDFLTHCPATGHHTSSNSHPTLASLPQASPHAGIKRLKLSVLAAMTVTALAACSSLPA
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQSDTDNKAARPAVSSADTHFADDDSRHEYQLDNGLKVIIKEDHRAPVAMTQIWYGVGST
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCEEHHHHHHCCCCC
DEPKDKGGISHLLEHMMFKGTKKVSGADFDRLIAKFGGDHNAFTSYDYTGYYEMFPVNRL
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCE
DLALELESDRMVNLRFDSDEFVQEFAQERNVVMEERRQRTDDNPLARAFEKFRKMALPDS
EEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
PKGESVIGPMDEIANTDIKDLQQWYDTWYAPNNATLVIVGDVNPKETLKKVEHYFGSIKH
CCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
KPIPQRPSVQQQAFRGYQQQTVKETVNVPTLIMAFNVPTLPSAITANSSDKEVYELLMLQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCHHHHHHHHHHH
YIMDGGYAARFEKNLVRKQGLLASVVAYYDAYERGDGLFMVQATPREGVSLAQAQKAIID
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
EMDTLKTQTISKQELERARNNAINGFVFSQDSMAGQANMIGSLQVRGLDDRLVTTLPDKL
HHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHCCEEEEEECCCCHHHHHHHHHH
AKVTSADVNAAASKYLVNNNLNVMYVEPAETRSVMPASNSMPAQPMPAKP
HHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTDFLTHCPATGHHTSSNSHPTLASLPQASPHAGIKRLKLSVLAAMTVTALAACSSLPA
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQSDTDNKAARPAVSSADTHFADDDSRHEYQLDNGLKVIIKEDHRAPVAMTQIWYGVGST
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCEEHHHHHHCCCCC
DEPKDKGGISHLLEHMMFKGTKKVSGADFDRLIAKFGGDHNAFTSYDYTGYYEMFPVNRL
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCE
DLALELESDRMVNLRFDSDEFVQEFAQERNVVMEERRQRTDDNPLARAFEKFRKMALPDS
EEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
PKGESVIGPMDEIANTDIKDLQQWYDTWYAPNNATLVIVGDVNPKETLKKVEHYFGSIKH
CCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
KPIPQRPSVQQQAFRGYQQQTVKETVNVPTLIMAFNVPTLPSAITANSSDKEVYELLMLQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCHHHHHHHHHHH
YIMDGGYAARFEKNLVRKQGLLASVVAYYDAYERGDGLFMVQATPREGVSLAQAQKAIID
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
EMDTLKTQTISKQELERARNNAINGFVFSQDSMAGQANMIGSLQVRGLDDRLVTTLPDKL
HHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHCCEEEEEECCCCHHHHHHHHHH
AKVTSADVNAAASKYLVNNNLNVMYVEPAETRSVMPASNSMPAQPMPAKP
HHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]